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Qaagi - Book of Why

Causes

Effects

by the activation and uncontrolled proliferation of T lymphocytes and well - differentiated macrophages(passive) to be caused by1 ] Macrophage activation syndrome

mutationcausesautoinflammation with recurrent macrophage activation syndrome

by excessive activation and proliferation of T lymphocytes and macrophages(passive) to be caused byMacrophage activation syndrome is thought

by excessive activation and proliferation of T lymphocytes and macrophages(passive) to be caused byMacrophage activation syndrome ( MAS

by the activation and uncontrolled proliferation of T lymphocytes and macrophages(passive) to be caused byMacrophage activation syndrome ( MAS

by the activation and uncontrolled proliferation of T lymphocytes and well - differentiated macrophages(passive) to be caused byMacrophage activation syndrome

by the immune disease irritating their mast cells so much(passive) caused bymast cell activation syndrome

the immune disease irritating their mast cells so much(passive) caused bymast cell activation syndrome

These inflammation phenotypescan leadto macrophage activation syndrome

These inflammation phenotypescan leadto macrophage activation syndrome Macrophage activation syndrome

Neurological symptoms associated with renal or liver impairment , fever , lymphadenopathy and disseminated intravascular coagulationshould promptconsideration of macrophage activation syndrome

Lyme diseasecan causeMast Cell Activation Syndrome

Lyme diseasecan causemast cell activation syndrome

Lyme diseasemay ... causemast cell activation syndrome

by Lyme Disease(passive) caused byMast Cell Activation Syndrome

many thingscan setoff mast cell activation syndrome

the activation and uncontrolled proliferation of T lymphocytes and well - differentiated macrophages , leading to widespread hemophagocytosis and cytokine overproduction [ 1,2,6(passive) to be caused byMacrophage activation syndrome

Relatedto causeactivation syndrome

any drugcausingACTIVATION SYNDROME

ASPIRIN ... other drugscauseACTIVATION SYNDROME

ACETAMINOPHEN ... other drugscauseACTIVATION SYNDROME

a possibilitycould causeActivation Syndrome

Tryptophancan causeactivation syndrome

CYMBALTA ... other drugscauseACTIVATION SYNDROME

CYMBALTAcausingACTIVATION SYNDROME

you evaluatecausesACTIVATION SYNDROME

you evaluateACETAMINOPHEN causesACTIVATION SYNDROME

Disposition of antidepressantscan causeactivation syndrome

Some of the injury stimulicausingendothelial dysfunction / activation

Reactivation of the virus in immunocompromised patientscausesactivation of latent virus

Cns ... the processresultsin the cell activation syndrome

RUNX1causesmethylation activation KMT2A ( MLL

chronic paincould influenceischemic AMPK activation

by block of the posterior(passive) caused byventricular activation

These data suggestcould be influencingmicroglia / macrophage activation

the cortex where these basal forebrain cholinergic neuronscausecortical activation

in turncausescortical activation

a peripheral stimuluscan causecortical activation

LPS - induced lung inflammationcausesmacrophage activation

the two viral infectionsto causemonocyte / macrophage activation

from uncontrolled activation and proliferation of T cellsto resultfrom uncontrolled activation and proliferation of T cells

from uncontrolled activation and proliferation of T cells and excessive activation of macrophagesto resultfrom uncontrolled activation and proliferation of T cells and excessive activation of macrophages

to the death of more than half of the patientsmay have contributedto the death of more than half of the patients

in deathresultsin death

to ongoing health problemsleadingto ongoing health problems

severe allergic - like symptomscausessevere allergic - like symptoms

severe organ inflammationis causingsevere organ inflammation

specific symptoms(passive) caused byspecific symptoms

temporary symptomscan causetemporary symptoms

alsocan ... causealso

temporary symptoms in multiple organ systemscan causetemporary symptoms in multiple organ systems

allergic reactioncausesallergic reaction

histamine intolerancecauseshistamine intolerance

the release of histamine , a substance that causes chronic inflammationcausesthe release of histamine , a substance that causes chronic inflammation

the POTSis causingthe POTS

in pulmonary diseasecan resultin pulmonary disease

headachescan causeheadaches

any harmmay causeany harm

in animalsmay resultin animals

to inflammation and neuronal injury in a number of neurological disorders [ 2 , 3contributesto inflammation and neuronal injury in a number of neurological disorders [ 2 , 3

the graft(passive) caused bythe graft

in very high fatality in childrenresultsin very high fatality in children

the oxidative burst(passive) caused bythe oxidative burst

to removal of cellular debris and protein aggregates by phagocytosis and 2 ) ITGB3 , Galctin-3 and TGFB1leadsto removal of cellular debris and protein aggregates by phagocytosis and 2 ) ITGB3 , Galctin-3 and TGFB1

oftenleadsoften

to the release of proinflammatory cytokines , reactive oxygen species ( ROS ) , proteolytic enzymes involved in matrix degradation and thus in atherosclerotic plaque destabilizationleadsto the release of proinflammatory cytokines , reactive oxygen species ( ROS ) , proteolytic enzymes involved in matrix degradation and thus in atherosclerotic plaque destabilization

to the observed responsecontributeto the observed response

to the control of the disease and to the immunosuppression observed during the course of the infectioncontributesto the control of the disease and to the immunosuppression observed during the course of the infection

to the activation of stellate cellscontributesto the activation of stellate cells

to production of tumor necrosis factor ( TNF - leadingto production of tumor necrosis factor ( TNF -

in increased phagocytosisresultingin increased phagocytosis

to the pathogenesis of inflammatory diseases including atherosclerosiscontributes importantlyto the pathogenesis of inflammatory diseases including atherosclerosis

to sustained recruitment of CCR5leadsto sustained recruitment of CCR5

to inflammationleadsto inflammation

to a Cellleadsto a Cell

to production ofleadingto production of

in the release oresultingin the release o

to growth or differentiationleadingto growth or differentiation

to Ca++ entry into the cell triggering protein kinase C activationleadsto Ca++ entry into the cell triggering protein kinase C activation

injury to normal tissuescan causeinjury to normal tissues

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