the solubility of curcumin , which is very low in water , low intestinal permeability , and extensive first cross metabolism.[5(passive) is caused byLow bioavailability
by poor solubility in water(passive) caused possibly bylow bioavailability
Low solubilitycauseslow bioavailability
Example Poor solubilitycan causelow bioavailability
Poor solubilitycan causelow bioavailability
low solubility of APIs(passive) caused bylow bioavailability
by low solubility of APIs(passive) caused bylow bioavailability
the factorscausinglow bioavailability
often(passive) is ... causedLow serotonin
API , which has poorly soluble drugscan causelow bioavailability
problems of solubility and permeabilitycauseslow bioavailability
very low water solubilitycauseslow bioavailability
Impact of low bioavailability on efficacy and toxicitymay leadLow bioavailability
by inactivation during absorption by intestinal CYP3A4(passive) caused bylow bioavailability
some imbalance in the body , which means that finding and reversing that imbalance is necessary to maintain normal iron and ferritin levels(passive) is caused byLow ferritin
by adrenal insufficiency(passive) caused bylow aldosterone
by inadequate body fat stores(passive) caused byLow leptin
poor MTHFR functioncan causelow folate
conditionscauselow neutrophils
conditionscauselow neutrophils
All of these drugscan causelow aldosterone
the insufficient blood in kidney and injured renal cells and(passive) is caused byLow GFR
Very low serum iron ( anemiawould causelow ferritin
a methylation cycle block(passive) can be caused byLow methionine
to poor muscle formationwill definitely contributeto poor muscle formation
in reduced libido and general malaisecan resultin reduced libido and general malaise
cancercausingcancer
in depressionmay resultin depression
in depressionresultsin depression
insomnia , irritability , anxiety , and depressioncan causeinsomnia , irritability , anxiety , and depression
insomniadoes ... causeinsomnia
insomniacan ... causeinsomnia
insomnia Butcausesinsomnia But
insomniacauseinsomnia
higher cortisolcausinghigher cortisol
low glutathione and low glutathione causes high oxidative stresscauseslow glutathione and low glutathione causes high oxidative stress
in bone loss , depression , sexualcan also resultin bone loss , depression , sexual
decreased energymay causedecreased energy
to hungerleadsto hunger
Liver damage(passive) caused byLiver damage
to symptomscan leadto symptoms
in low ATPresultsin low ATP
to low testosteronecan contributeto low testosterone
insomnia with your physiciancauseinsomnia with your physician
typicallyresultstypically
chronic fatiguecauseschronic fatigue
to hunger and craving for carbohydratesleadsto hunger and craving for carbohydrates
from high epinephrinecan ... be causedfrom high epinephrine
in mitochondria deathresultsin mitochondria death
to a group of symptoms that resembles dementiacan leadto a group of symptoms that resembles dementia
both long - term and short - term memory loss and impair other cognitive functionscan causeboth long - term and short - term memory loss and impair other cognitive functions
both long - term and short - term memory loss and impair some cognitive functionscan causeboth long - term and short - term memory loss and impair some cognitive functions