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early prescribing decisionscan influencelong - term opioid use
depression or anxiety | Dr Lal Thadani | MD ( PSM(passive) may be triggered byLong term opioid use
that can helppreventlong - term opioid use
Future strategies , for better follow up of subjects after surgeryto preventlong - term opioid use
these prescriptioncan ... influencelong - term opioid use
Dependence and likelihood of abusemay causeLong term opioid use
to increasecausingprolonged opioid use
a workplace injury(passive) triggered bylong - term opioid use
Identification of high - risk patient while they are still in the acute or subacute treatment window and subsequent referral to pain specialistsmay preventlong - term opioid use
a legitimate hospital or doctor visit(passive) sparked bylong - term opioid use
emergency department prescriptionscan influencelong - term opioid use
offer key therapeutic targets for the development of strategiesto preventprolonged opioid use
FactorsInfluencingLong - Term Opioid Use
Original article : intramuscular ketorolac versus diclofenac in acute renal colic : a renal colic 6 howevermay causeprolonged opioid use
we need guidelines about appropriate prescribing at dischargeto preventlong term [ opioid ] use
to tolerance , dependence , addiction , andledto tolerance , dependence , addiction , and
to addiction or dependencecan leadto addiction or dependence
to abuse and addictioncan leadto abuse and addiction
to harmful addictionleadsto harmful addiction
opioid - induced hyperalgesia , which is a condition in which the patient has increased sensitivity to pain.[83can causeopioid - induced hyperalgesia , which is a condition in which the patient has increased sensitivity to pain.[83
opioid - induced hyperalgesia , which is a condition in which the patient has increased sensitivity to pain.[43can causeopioid - induced hyperalgesia , which is a condition in which the patient has increased sensitivity to pain.[43
Addiction in Bariatric Surgermay CauseAddiction in Bariatric Surger
to addiction that can cause other complicationscan leadto addiction that can cause other complications
to the development of tolerance , hyperalgesia , dependency , or addictionmay leadto the development of tolerance , hyperalgesia , dependency , or addiction
Addiction in Bariatric Surgery Patientsmay CauseAddiction in Bariatric Surgery Patients
secondary hypogonadism , which may lead to sexual dysfunction , infertility , mood disorders , and osteoporosis ( Brennan , 2013).• Biliary tract impairment : Use with caution in patients with biliary tract dysfunction and acute pancreatitismay causesecondary hypogonadism , which may lead to sexual dysfunction , infertility , mood disorders , and osteoporosis ( Brennan , 2013).• Biliary tract impairment : Use with caution in patients with biliary tract dysfunction and acute pancreatitis
to many health issues , the most serious being addiction and fatal overdosescan leadto many health issues , the most serious being addiction and fatal overdoses
in a slew of problems , including the risk of addictionresultsin a slew of problems , including the risk of addiction
to bad results in other areas , including addiction and overdosecan leadto bad results in other areas , including addiction and overdose
to tolerance , hyperalgesia , dependence , andcan leadto tolerance , hyperalgesia , dependence , and
physiological dependence ( a phenomenon distinct from addiction ) , which generates additional clinical complexitycausesphysiological dependence ( a phenomenon distinct from addiction ) , which generates additional clinical complexity
oftenleadsoften
to opioid - induced hyperalgesia ( OIH ) or greater pain sensitivitycan leadto opioid - induced hyperalgesia ( OIH ) or greater pain sensitivity
physical dependence as well as opioid - induced hyperalgesia , which is an abnormally increased sensitivity to paincan causephysical dependence as well as opioid - induced hyperalgesia , which is an abnormally increased sensitivity to pain
physical changes in the brain(passive) caused byphysical changes in the brain
to very serious conditions , like physical dependency and hyperalgesiacan ... leadto very serious conditions , like physical dependency and hyperalgesia
harmful side effects(passive) caused byharmful side effects
significant decreases in pain tolerancealmost always causessignificant decreases in pain tolerance
significantly decreased pain toleranceto causesignificantly decreased pain tolerance
adrenal insufficiency ( nausea , vomiting , anorexia , fatigue , weakness , dizziness and low blood pressure ) or secondary hypogonadism , which may lead to sexual dysfunction , infertility , mood disorders , and osteoporosis ( Brennan 2013may causeadrenal insufficiency ( nausea , vomiting , anorexia , fatigue , weakness , dizziness and low blood pressure ) or secondary hypogonadism , which may lead to sexual dysfunction , infertility , mood disorders , and osteoporosis ( Brennan 2013
secondary hypogonadism , which may lead to sexual dysfunction , infertility , mood disorders , and osteoporosis ( Brennan , 2013).• CNS effects ... May cause CNS depression , which may impair physical or mental abilitiesmay causesecondary hypogonadism , which may lead to sexual dysfunction , infertility , mood disorders , and osteoporosis ( Brennan , 2013).• CNS effects ... May cause CNS depression , which may impair physical or mental abilities
to : Drug tolerancecan leadto : Drug tolerance
in an increased tolerancecan resultin an increased tolerance
secondary hypogonadism , which may lead to sexual dysfunction , infertility , mood disorders , and osteoporosis ( Brennan 2013).• Biliary tract impairment : Use with caution in patients with biliary tract dysfunction including acute pancreatitismay causesecondary hypogonadism , which may lead to sexual dysfunction , infertility , mood disorders , and osteoporosis ( Brennan 2013).• Biliary tract impairment : Use with caution in patients with biliary tract dysfunction including acute pancreatitis
to a downhill spiral associated with a loss of functional capacity and depressed mood ( Ciccone et al . , 2000ledto a downhill spiral associated with a loss of functional capacity and depressed mood ( Ciccone et al . , 2000
secondary hypogonadism , which may lead to sexual dysfunction , infertility , mood disorders , and osteoporosis ( Brennan , 2013).• Biliary tract impairment : Use oxycodone with caution in patients with biliary tract dysfunction , including acute pancreatitismay causesecondary hypogonadism , which may lead to sexual dysfunction , infertility , mood disorders , and osteoporosis ( Brennan , 2013).• Biliary tract impairment : Use oxycodone with caution in patients with biliary tract dysfunction , including acute pancreatitis
greater pain sensitivity leading to a syndrome called opioid induced hyperalgesiamay causegreater pain sensitivity leading to a syndrome called opioid induced hyperalgesia
to physical dependence and intense withdrawalcan leadto physical dependence and intense withdrawal
a paradoxical condition called opioid - induced hyperalgesia , where the drug can actually worsen and prolong paincan causea paradoxical condition called opioid - induced hyperalgesia , where the drug can actually worsen and prolong pain
to profound changes in brain chemistrycan leadto profound changes in brain chemistry
in hyperalgesia in which there is a lowering of the pain thresholdcan resultin hyperalgesia in which there is a lowering of the pain threshold
to opioid - induced hyperalgesia , which causes a patient to have increased sensitivity to pain – the opposite of what the medication is intended forcan then leadto opioid - induced hyperalgesia , which causes a patient to have increased sensitivity to pain – the opposite of what the medication is intended for
patients to perceive pain even after the original cause of pain has clearedcan causepatients to perceive pain even after the original cause of pain has cleared
to shortness of breath , heart problems , drowsiness , addiction , sleeping disorders , tooth decay and overdoseleadsto shortness of breath , heart problems , drowsiness , addiction , sleeping disorders , tooth decay and overdose
a greater sensitivity to pain(passive) caused bya greater sensitivity to pain