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Qaagi - Book of Why

Causes

Effects

admixture with O. sativa and ecological adaptation Semon , M.(passive) caused bylinkage disequilibrium

hitchhiking(passive) created bylinkage disequilibrium

post - glaciation admixturecreatedlinkage disequilibrium

because population admixture has been knownto createlinkage disequilibrium

Q.What information about recombination frequencies enables scientiststo createlinkage maps?A.

recent popu - lation admixture(passive) caused bylinkage disequilibrium

selection , genetic drift or admixture of populations with different gametic frequencies ( Mueller , 2004(passive) created bylinkage disequilibrium

selection on G6PD in humans AU - Saunders , Matthew A. N2(passive) caused bylinkage disequilibrium

either genetic drift or disruptive selection on epistatic loci ( Futuyma and Philippi , 1987(passive) caused bylinkage disequilibrium

to mutation , selection , and driftcausinglinkage disequilibrium

past natural selection on eyespot size(passive) created bylinkage disequilibrium

introgression and phenotypic selection(passive) created bylinkage disequilibrium

many factors , including selection , the rate of recombination , the rate of mutation , genetic drift , the system of mating , population structure , and genetic linkage(passive) is influenced byLinkage disequilibrium

many factors , including selection , the rate of genetic recombination , mutation rate , genetic drift , the system of mating , population structure , and genetic linkage(passive) is influenced byLinkage disequilibrium

tic as one stop shop background on the Natural SelectionCan CreateLinkage Disequilibrium

selection on G6PD in humans M A Saunders , M Slatkin , C Garner , M F Hammer , and M W Nachman(passive) caused bylinkage disequilibrium

random genetic drift ... whereas , in the present study , the disequilibrium was initially created by the occurrence of a mutation in a single haplotype , which is probably less variable(passive) was caused bythe linkage disequilibrium

when populations are small , and gets shorter as random shuffling between chromosomes breaks it down(passive) is createdLinkage disequilibrium

Ma- binary options channel back factorsinfluencinglinkage disequi-

mutation Eliminated by selection fixation Factors affecting fixation of a polymorphism(passive) Created bylinkage disequilibrium

the rate of recombination ; mutation rate ; random drift or non- > random mating ; and population structure(passive) is ... causedLinkage disequilibrium

The bottleneck involved in the domestication process and more importantly the selection of multi - genic traits encompassing long haplotypes from different chromosomescould causelinkage disequilibrium

that , after reassortment , unattached lineages mass different mutations on dif- ferent segments and store those supplementary mutations together within the lin- eagecreatinglinkage disequilibrium

the mixture of multiple gene pools(passive) created bylinkage disequilibrium

population structure and familial relatedness(passive) caused byLinkage disequilibrium

a low frequency of recombinations between two loci(passive) can be caused byLinkage disequilibrium

keep those new mutations together within the lin- eagecreatinglinkage disequilibrium

While loci were selected across chromosomesto preventlinkage disequilibrium

chromosomal inversioncausinglinkage disequilibrium

selection for resistance(passive) caused bylinkage disequilibrium

A basic assumption of the IBD method ... i.e. , the eventcreatedlinkage disequilibrium

inter - marker occurrence and missing parental genotype information(passive) caused bylinkage disequilibrium

only shared polymorphic sitescontributelinkage disequilibrium

differentiation(passive) created bylinkage disequilibrium

Population bottlenecksfrequently causelinkage disequilibrium

linked selectioncan createlinkage disequilibrium

association mapping ... where it is not easyto createlinkage disequilibrium

sampling(passive) caused bylinkage disequilibrium

to move the # sign outside of the bracketto createlinkage ( lgale

pooling genetically distinct subpopulations , as shown in Chapter 3(passive) can also be created byLinkage disequilibrium

us to describe two new risk haplotypes ( DQA1 * 0101-DQB1 * 0501-TNFa2b1 and DQA1leadingus to describe two new risk haplotypes ( DQA1 * 0101-DQB1 * 0501-TNFa2b1 and DQA1

the difference between causal and marker SNP frequencies , haplotype number , haplotype diversity , and window sizecontributethe difference between causal and marker SNP frequencies , haplotype number , haplotype diversity , and window size

misleading or synthetic associations in genome - wide association studiescan causemisleading or synthetic associations in genome - wide association studies

from natural selection of certain combination of allelesmay resultfrom natural selection of certain combination of alleles

The equilibrium genetic covariance between pairs of characters under correlational selection(passive) is caused byThe equilibrium genetic covariance between pairs of characters under correlational selection

Another difficulty(passive) caused byAnother difficulty

test statistics between markers to be correlatedcausestest statistics between markers to be correlated

from natural selection of a particular combination of allelesmay resultfrom natural selection of a particular combination of alleles

for examplemay resultfor example

to either over- or under - estimation of the true number of eplet mismatches between donors and recipientscan leadto either over- or under - estimation of the true number of eplet mismatches between donors and recipients

The genome - wide effect on allele frequencies in the mixed population(passive) may be caused byThe genome - wide effect on allele frequencies in the mixed population

difficulties to pinpoint the causative genes and variationscreatesdifficulties to pinpoint the causative genes and variations

the accuracy of imputing missing valuesinfluencesthe accuracy of imputing missing values

transcripts in local regions to be highly correlatedcausestranscripts in local regions to be highly correlated

allele frequency changes for markers linked and unlinked to the Plasmodium - resistant loci needs further investigation using empirical and theoretical approachesmay have causedallele frequency changes for markers linked and unlinked to the Plasmodium - resistant loci needs further investigation using empirical and theoretical approaches

alsomay ... causealso

the test statistics and effect size estimates at the tag and causal SNPs to be correlatedcausesthe test statistics and effect size estimates at the tag and causal SNPs to be correlated

ambiguity because many markers can act as proxies for others and complex forms of epistasis are bound to produce havoc in a naive linear model on additive effectscreatesambiguity because many markers can act as proxies for others and complex forms of epistasis are bound to produce havoc in a naive linear model on additive effects

when testing for epistatic interactions between DNA markerscan createwhen testing for epistatic interactions between DNA markers

the correlations with other SNPs in the region(passive) caused bythe correlations with other SNPs in the region

from reduced gene flow due to geographic separationcan resultfrom reduced gene flow due to geographic separation

to extensive correlationsleadingto extensive correlations

to over estimation of genetic variancesleadingto over estimation of genetic variances

correlation(passive) caused bycorrelation

interaction(passive) caused byinteraction

to commonly coinherited haplotypesleadingto commonly coinherited haplotypes

up for MX racingsetup for MX racing

from historical evolutionary processesresultingfrom historical evolutionary processes

a matching OTcl object for each of the C++createa matching OTcl object for each of the C++

the possible bias(passive) caused bythe possible bias

to a 100 Kb haplotype , called H1 , which may contain pathogenic mutations or other genetic variations which increase the susceptibility to PSP.10leadingto a 100 Kb haplotype , called H1 , which may contain pathogenic mutations or other genetic variations which increase the susceptibility to PSP.10

to association of disease MTRF1 risk in tagging SNPs at neighboring genomic loci.16 18 A lot more than 30 % of African Americansleadsto association of disease MTRF1 risk in tagging SNPs at neighboring genomic loci.16 18 A lot more than 30 % of African Americans

to Figure 1leadingto Figure 1

Little ROCK Haplotype AC and Haplotype GT(passive) created byLittle ROCK Haplotype AC and Haplotype GT

identification of causal variantspreventsidentification of causal variants

of blocks of sequence with average size of 7.8 kb and could be used in association studiesis composedof blocks of sequence with average size of 7.8 kb and could be used in association studies

through the history of the populationcreatedthrough the history of the population

genetic effects(passive) caused bygenetic effects

from spurious correlations in laboratory strainsmight have resultedfrom spurious correlations in laboratory strains

in a cross of inbred materialscreatedin a cross of inbred materials

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