AB - The structural modifications on the B - region of the potent and high affinity vanilloid receptor ( VR1leadligand N-(3-acyloxy-2-benzylpropyl)-
to provide the linkage between chemical & biological aspects of life in light of enzymatic reactions(passive) is designedLIGAND
6 ) TABLE 5 FKBP-12 in vitro binding assayresultsLigand
pharmacological or genetic inhibition of ATR , ATM or Chk1 ( a downstream transducer kinase in the pathway(passive) was prevented byLigand upregulation
The absence of one SpreventsCys ligand
Monoclonal antibodies and anti - TGF - β drugscan preventligand
rat bone marrow - derived cellscan contributeto the ligand
Mutations in both genesleadto ligand
This antibody makesto preventligand
DOI : 10.1002 / anie.201205840 Using Ligand - Mapping Simulationsto Designa Ligand
In these cases , the differences between the test compound concentration and the rapamycin control concentration were taken into account using equation 6 below : [ 0000 ] TABLE 5 FKBP-12 in vitro binding assayresultsLigand
control of all of the conformational statescontributeto ligand
e.g. , � C6H5resultingligand : H2(ppb
how one specific multi - targetdesignedligand ( MTDL
For example , bevacizumab targets VEGF - Ato causeligand sequestering
Onartuzumab ... a single - arm antibodypreventsligand
growth necrosis factor - related apoptosiscausingligand ( TRAL
the GUM scope , the largest way use in the cybersecurity(passive) is painted bythe ligand-
An important pH in Pre - NOTCH horizon in the Golgileadsligand
one cell ties to a receptor in the extracellular area of another cell(passive) created byA ligand
of one pyridine unit and two n - butyl - substituted pyrazoles ( pyrz(passive) is composedThe ligand
Binding ability of the adsorbed ligate ( Monoclonal antibody ) to the radiolabelledligand ( chg
intermolecular H - bonding effects as well as steric and electronic factorsinfluencethe ligand
Ramucirumab , a human IgG1 monoclonal antibody directed to the ectodomain of VEGFR-2preventsligand
one - bead - one - compound combinatorial technology as a potent and specific EPC / EC targeting ligand(passive) discovered byligand LXW7
to target many different tumor proteins , such as the folate receptor , which is present on about one - third of human cancers , and prostate - specific membrane antigen , which is present in prostate cancer tumors(passive) can be designedThe ligand
of two parts , one carrying the activity ( agonist or antagonist ) at the different subtypes of OR , the “ message ” and one part , the “ address , ” conveying selectivity toward a given OR ( Portoghese et al . , 1990(passive) is composedthe ligand
Cells were first incubated with a mixture of metabolic inhibitors ( 50 mmol / L 2-deoxy - D - glucose , 15 mmol / L NaN3 , and 1 mg / mL BSA in PBSto preventligand internalization
to bind Ln(III(passive) has been designedThe ligand
the potential redox noninnocence of hydrazido ligandscould leadto ligand-
on HLA - E(passive) is composedThe ligand
from attaching to the surface via sites important to the interaction under study by having analyte present during immobilization(passive) may be preventedThe ligand
considerable effortdesigningthe ligand
the metal complex(passive) contributed bya ligand
The complex between the ligand and the soluble receptorpreventsthe ligand
the agent being tested(passive) caused bya ligand
The Sixth Editioncausesthe ligand
to fullfill the requirement(passive) was designedOne ligand
to Isolation of Low - Coordinate Transition Metal Complexes , AngewLeadsto Isolation of Low - Coordinate Transition Metal Complexes , Angew
allergen - induced airway hyperresponsiveness and eosinophilia in allergic asthma by a MYD88-dependent and MK2-independent pathwayAbstractFulltextPDFWeb of Science ... 39)Scopuspreventsallergen - induced airway hyperresponsiveness and eosinophilia in allergic asthma by a MYD88-dependent and MK2-independent pathwayAbstractFulltextPDFWeb of Science ... 39)Scopus
dimerization of receptorcausesdimerization of receptor
allergen - induced airway hyperresponsiveness and eosinophilia in allergic asthma by a MYD88-dependent and MK2-independent pathwayAbstractFulltextPDFRole of Breast Milk in a Mouse Model of Maternal Transmission of Asthmapreventsallergen - induced airway hyperresponsiveness and eosinophilia in allergic asthma by a MYD88-dependent and MK2-independent pathwayAbstractFulltextPDFRole of Breast Milk in a Mouse Model of Maternal Transmission of Asthma
activation of the kinase VEGFRpreventsactivation of the kinase VEGFR
allergen - induced air Structural equation modeling of gene - environment interactions in coronary heart diseasepreventsallergen - induced air Structural equation modeling of gene - environment interactions in coronary heart disease
on the structures of copper molybdate chainsinfluenceson the structures of copper molybdate chains
frequentlycausedfrequently
several orally active , non - steroidal SARM compounds based on tissue - specific gene expression and other functional , cell - based technologieshas discoveredseveral orally active , non - steroidal SARM compounds based on tissue - specific gene expression and other functional , cell - based technologies
to receptor mediated internalization of NPs into the cells [ 14leadsto receptor mediated internalization of NPs into the cells [ 14
novel research and technologies for approved medicines that treat cancer , osteoporosis , fungal infections , low blood platelets , among othershas contributednovel research and technologies for approved medicines that treat cancer , osteoporosis , fungal infections , low blood platelets , among others
interleukin-6 secretion in multiple myeloma M Urashima , D Chauhan , H Uchiyama , GJ Freeman and KC Anderson Blood 1995triggeredinterleukin-6 secretion in multiple myeloma M Urashima , D Chauhan , H Uchiyama , GJ Freeman and KC Anderson Blood 1995
the SARM LGD-2941 , which TAP is developing in a Phase I clinical trialdiscoveredthe SARM LGD-2941 , which TAP is developing in a Phase I clinical trial
platelet release of reactive oxygen intermediates Textinfluencesplatelet release of reactive oxygen intermediates Text
in resolution of PCOS - associated endocrine and metabolic disturbances and restored reproductive functionresultedin resolution of PCOS - associated endocrine and metabolic disturbances and restored reproductive function
of unsubstituted or substituted mono- , bi- or multicyclic ring systems selected from aromatic or non - aromatic or partially saturated ring systems and containing carbon ring atoms and optionally one or more heteroatoms selected from Groups 15 and 16 of the Periodic Tablecomposedof unsubstituted or substituted mono- , bi- or multicyclic ring systems selected from aromatic or non - aromatic or partially saturated ring systems and containing carbon ring atoms and optionally one or more heteroatoms selected from Groups 15 and 16 of the Periodic Table
conformational change of VDR - RXR heterodimerstriggeredconformational change of VDR - RXR heterodimers
in signal activation or inhibitionresultingin signal activation or inhibition
the phosphorylation of c - Fos(passive) triggered bythe phosphorylation of c - Fos
the strength of bindingstrongly influencesthe strength of binding
binding and dimerizationcausesbinding and dimerization
novel , selective , small moleculehas discoverednovel , selective , small molecule
transcription elements and constituent transcriptional repressors20 encoded from the genes and respectivelytriggeredtranscription elements and constituent transcriptional repressors20 encoded from the genes and respectively
autocrine signaling in acute myeloid leukemia cells — Johns Hopkins Universitycausesautocrine signaling in acute myeloid leukemia cells — Johns Hopkins University
binding of TK receptor subunitscausesbinding of TK receptor subunits
activation energy(passive) caused byactivation energy
to receptor clusteringleadingto receptor clustering
receptor interactionsleadreceptor interactions
trimerization of their receptorwould causetrimerization of their receptor
strong TCR /causesstrong TCR /
binding of the agonist ... either directly ( competitive binding ) or indirectly ( allostericpreventsbinding of the agonist ... either directly ( competitive binding ) or indirectly ( allosteric
of CD40 on DC 10 , 11triggeringof CD40 on DC 10 , 11
zantac usa bindingcauseszantac usa binding
to a distortion of the binding parametercould ... leadto a distortion of the binding parameter
Changes in protein conformation(passive) triggered byChanges in protein conformation
the Drosophila JNK pathwaytriggersthe Drosophila JNK pathway