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Qaagi - Book of Why

Causes

Effects

Increased wall thickness of the interventricular septum and protrusion of the MV into the outflow pathcontributeto left ventricular outflow tract obstruction ( LVOTO

intact ventricular septumcausingsevere left ventricular outflow tract obstruction

the mitral valvecausingsevere left ventricular outflow tract obstruction

Subaortic MembranecausingSevere Left Ventricular Outflow Tract Obstruction

Al - Farqani A. Accessory mitral valve tissuecausingsevere left ventricular outflow tract obstruction

the mitral valvemay causeleft ventricular outflow tract obstruction ( LVOTO

by the systolic anterior movement of the mitral(passive) caused byleft ventricular outflow tract obstruction ( LVOTO

the systolic anterior movement of the mitral valve(passive) caused byleft ventricular outflow tract obstruction ( LVOTO

rhabdomyoma(passive) caused byleft ventricle outflow tract ( LVOT ) obstruction

A five - month - old baby presented with a myxoma arising from the anterior , lateral , and superior aspect of the LVcausingsevere left ventricular outflow tract obstruction

This stenosiscausesa left ventricular outflow tract ( LVOT ) obstruction

Hypertrophic obstructive cardiomyopathy hocm septal hypertrophyoften causingleft ventricular outflow tract lvot obstruction

abnormal thickening from hypertrophic cardiomyopathy(passive) can be caused byLeft Ventricle Outflow Tract Obstruction Left ventricular outflow tract obstruction

Some lesionscausingleft outflow tract obstruction

by mitral systolic anterior motion(passive) caused byventricular outflow tract obstruction

by a membranous lesion(passive) caused bya left - ventricular outflow tract ( LVOT ) obstruction

the interventricular septumcausingintermittent obstruction of the left ventricular outflow tract

Anomalous Papillary Muscle and Subaortic Membrane(passive) Caused byCorrection of Left Ventricular Outflow Tract Obstruction

afterload reduction induced by intra - aortic balloon counterpulsation(passive) caused byventricular outflow tract obstruction

the anterior interventricular septumcausinga left ventricular outflow tract obstruction

systolic anterior motion of the mitral valve(passive) caused byleft ventricular outflow tract obstruction

septal aneurysmcausingright ventricular outflow tract obstruction

the mitral valveleadingto subaortic left ventricular outflow tract obstruction

> MITRAL VALVE DISEASE > Accessory Mitral Valve TissuecausingLeft Ventricular Outflow Tract Obstruction

MITRAL VALVE DISEASE - Accessory Mitral Valve TissuecausingLeft Ventricular Outflow Tract Obstruction

by a right coronary (passive) caused byRight ventricular outflow tract obstruction

by mitral systolic anterior motion(passive) caused byleft ventricular outflow tract obstruction

membranous septal aneurysmcausingright ventricular outflow tract obstruction

mitral valve tissuecausingleft ventricular outflow tract obstruction

interventricular septumcausingleft ventricular outflow tract obstruction

Abnormal anterior papillary musclecausingobstruction of the left ventricular outflow tract

the septumcausesthe left ventricular outflow tract obstruction

by accessory mitral valve tissue(passive) caused byLeft ventricular outflow tract obstruction

Accessory mitral valve tissuecausingleft ventricular outflow tract obstruction

- Accessory mitral valve tissuecausingleft ventricular outflow tract obstruction

Hypertrophic cardiomyopathy ( HCM ... an autosomal - dominant inheritancecan causeobstruction in the left ventricle outflow tract

the mitral valveleadingto left ventricular outflow tract obstruction

mitral valvecausingleft ventricular outflow tract obstruction

Some patients ... very complicated abnormalitiescauseobstruction of the left ventricular outflow tract

the muscular septumcausingobstruction to the left ventricular outflow tract

patients with disabling symptoms(passive) caused bypatients with disabling symptoms

syncope(passive) caused bysyncope

deficient Notch1 protein localization induced by receptor retention in the ERcausesdeficient Notch1 protein localization induced by receptor retention in the ER

sequelae of syncope(passive) caused bysequelae of syncope

to heart failure due to diastolic dysfunctioncan leadto heart failure due to diastolic dysfunction

heart failure , chest pain , arrhythmias , syncope , or deathcan causeheart failure , chest pain , arrhythmias , syncope , or death

symptoms ... , either at rest or during effort(passive) caused bysymptoms ... , either at rest or during effort

relief symptoms(passive) caused byrelief symptoms

relief symptoms(passive) caused byrelief symptoms

again , LVOT'll ... discoveragain , LVOT

hypertrophy(passive) caused byhypertrophy

hydrocephaluscausinghydrocephalus

to decreased cerebral blood flowleadingto decreased cerebral blood flow

to venous hypertensionleadingto venous hypertension

more than mild hypertrophy , abnormal coronary blood flow , and diastolic and systolic LV dysfunction that act in concert to cause symptoms , LV damage , and cardiac deathcausesmore than mild hypertrophy , abnormal coronary blood flow , and diastolic and systolic LV dysfunction that act in concert to cause symptoms , LV damage , and cardiac death

to portal hypertensionleadsto portal hypertension

pelvic congestion syndrome(passive) caused bypelvic congestion syndrome

to ischemialeadsto ischemia

progressive and drug - refractory heart failure(passive) caused byprogressive and drug - refractory heart failure

a Budd - Chiari - like congestion of the livercausinga Budd - Chiari - like congestion of the liver

pressure load(passive) caused bypressure load

to hypertrophy and reduced diastolic functionleadingto hypertrophy and reduced diastolic function

more than mild hypertrophycausesmore than mild hypertrophy

sudden cardiac deathmay ... causesudden cardiac death

heart failure and systemic congestion(passive) caused byheart failure and systemic congestion

to strain and hypertrophy of the LVleadsto strain and hypertrophy of the LV

from wide range of movements of graft in large sub hepatic spacecan resultfrom wide range of movements of graft in large sub hepatic space

to elevated IOP , choroidal effusions , and blood in the Schlemm canalleadsto elevated IOP , choroidal effusions , and blood in the Schlemm canal

from a severely hypertrophied interventricular septumcan resultfrom a severely hypertrophied interventricular septum

subaortic stenosis(passive) caused bysubaortic stenosis

to thickening of the right ventricle , or right ventricular hypertrophyleadsto thickening of the right ventricle , or right ventricular hypertrophy

to decreased cerebral blood flowleadingto decreased cerebral blood flow

extrinsiccausingextrinsic

significant outflow tract obstruction [ Figure 1causingsignificant outflow tract obstruction [ Figure 1

severe aortic regurgitation causingsevere aortic regurgitation

severe aortic regurgitationcausingsevere aortic regurgitation

severe mitral insufficiencycausingsevere mitral insufficiency

SAMcausingSAM

strokecausingstroke

mild associated flow acceleration ( Figure 3causingmild associated flow acceleration ( Figure 3

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