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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

the conditionscan causechromosome breakage

that indicatemay causechromosome breakage

That LSDcauseschromosome breakage

DNA double - strand breaks produced by ionising radiation are often misrejoinedto causechromosome exchange aberrations

The dicentric chromosomes generated by telomere fusionscan causechromosome breakage

Ozonecauseschromosome aberration

the Philadelphia chromosome or the fused BCR - ABL generesultsfrom the chromosome translocation

using radiationto causechromosome breakages

cells ... clastogenic agentscausechromosome breakages

Chromosome breakagecan resultin CHROMOSOME TRANSLOCATION

the mechanismscausingchromosome aberrations in

by radiation(passive) caused bychromosome aberrations

RET rearrangement is the commonest oncogenic alterations in Chernobyl - related PTC ; nearly all to RET / PTC1 or RET / PTC3resultingfrom paracentric inversion of chromosome 10

Such telomere damagecould causechromosome aberrations

by ionising radiation(passive) caused bychromosome aberrations

DNA damageleadsto chromosome translocation

humanscausingchromosome aberrations

clastogeniccausingchromosome aberrations

Ionizing radiation ... the initiating factors of CMLleadsto chromosome translocation

by X - ray irradiation(passive) caused bychromosome aberrations

and to what extentcausedchromosome aberrations

acute ATR inhibitioninfluenceschromosome translocation

clastogenic ( ... ) compounds [ 4causingchromosome aberrations

power - frequency fieldscould causechromosome aberrations

the mechanismscauseaberrant chromosome /

the underlying molecular mechanismsresultingin chromosome aberrations

as free radicals are emitted in the process of breaking downalso resultingin chromosome aberrations

anti - tumor preparations(passive) caused bychromosome aberrations

High concentrations have been reportedto causechromosome damage606

This combinationresultsfrom chromosome inversion

by two particular chromosomes joining together(passive) caused bychromosome rearrangement

Spatial orientationinfluenceschromosome ' switching

when there are two breaks in one chromosome and(passive) is causedA chromosomal inversion

when there are two breaks in one chromosome and the area between the breaks(passive) is causedA chromosomal inversion

mutationscausingmycobacteria chromosome

by three breaks in the same chromosome(passive) caused byA chromosomal inversion

any drugcausingFOETAL CHROMOSOME

BBS - associated ligasesleadchromosome progenitors

by three breaks(passive) caused byA chromosomal inversion

It may reattach back to the original chromosome , but in reverse orientationcausingchromosomal inversion

to a fusion geneleadsto a fusion gene

in a fusion generesultsin a fusion gene

to a fusion with the echinoderm microtubule - associated protein like 4 ( EML4 ) gene , which results in the abnormal expression and activation of this tyrosine kinase in the cytoplasm of cancer cellsleadingto a fusion with the echinoderm microtubule - associated protein like 4 ( EML4 ) gene , which results in the abnormal expression and activation of this tyrosine kinase in the cytoplasm of cancer cells

miscarriage in 30 % of the cases ... but 1can causemiscarriage in 30 % of the cases ... but 1

to disruption of the hlcs geneleadingto disruption of the hlcs gene

to the over expression of the MALT1 gene , trisomy 3 , trisomy 18 , and deletions at position 23 on the long arm of chromosome 6leadsto the over expression of the MALT1 gene , trisomy 3 , trisomy 18 , and deletions at position 23 on the long arm of chromosome 6

in Alpha - TFEB gene fusion [ PMID11395386resultingin Alpha - TFEB gene fusion [ PMID11395386

to the adaptation of An . gambiae ( s.s . ... to arid conditions [ 6 , 9 , 15contributesto the adaptation of An . gambiae ( s.s . ... to arid conditions [ 6 , 9 , 15

First Down Syndrome(passive) is caused byFirst Down Syndrome

to loss of genetic information , aberrant rearrangements of chromosomesleadingto loss of genetic information , aberrant rearrangements of chromosomes

to loss of genetic information , aberrant rearrangements of chromosomes , and genomic instabilityleadingto loss of genetic information , aberrant rearrangements of chromosomes , and genomic instability

to this diseasecan leadto this disease

The condition(passive) is caused byThe condition

the deletion in the child 's chromosome via a non - allelic homologous recombination ( NAHR ) mechanisminfluencesthe deletion in the child 's chromosome via a non - allelic homologous recombination ( NAHR ) mechanism

in chromosome disordersmay resultin chromosome disorders

in CHROMOSOME DISORDERS.may resultin CHROMOSOME DISORDERS.

in exchange of genetic material between the chromosomesresultsin exchange of genetic material between the chromosomes

to cancer and/orleadto cancer and/or

in CHROMOSOME DISORDERS.Radiation Injuriesmay resultin CHROMOSOME DISORDERS.Radiation Injuries

microdeletion syndromecausesmicrodeletion syndrome

from double - strand DNA breaks at a naturally occurring yeast fragile site composed of inverted ty elementsresultingfrom double - strand DNA breaks at a naturally occurring yeast fragile site composed of inverted ty elements

to the fusion of the anaplastic lymphoma kinase ( ALK ) gene with the echinoderm microtubule - associated protein - like 4leadingto the fusion of the anaplastic lymphoma kinase ( ALK ) gene with the echinoderm microtubule - associated protein - like 4

> Edwards syndrome(passive) is caused by> Edwards syndrome

to dominant expression of a second S layer proteinleadingto dominant expression of a second S layer protein

to retrocerebellar CSF spacecan leadto retrocerebellar CSF space

both Activation of a proto - oncogenecausingboth Activation of a proto - oncogene

disruption of replication(passive) caused bydisruption of replication

these discrepancies appear(passive) to have been caused bythese discrepancies appear

to cancerledto cancer

to our issuesis contributingto our issues

replication(passive) caused byreplication

According to the marker order in the genetic maps of these two chromosomes ( see Additional file 1 ) , these discrepancies appear(passive) to have been caused byAccording to the marker order in the genetic maps of these two chromosomes ( see Additional file 1 ) , these discrepancies appear

meiotic drivecan causemeiotic drive

to the identification of the Neuregulin-1 gene ( NRG1 ) as a potential genetic risk factorledto the identification of the Neuregulin-1 gene ( NRG1 ) as a potential genetic risk factor

tumorigenesis and breast cancer developmentalso influencetumorigenesis and breast cancer development

to genome heterozygosity of the two closely related haploid strains ... and the meiotic recombination between the two homoeologous chromosomes generates both inviable and viable SAN progenyleadsto genome heterozygosity of the two closely related haploid strains ... and the meiotic recombination between the two homoeologous chromosomes generates both inviable and viable SAN progeny

almost 50 % of the cases of severe Factor VIII deficiencycausesalmost 50 % of the cases of severe Factor VIII deficiency

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Smart Reasoning:

C&E

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