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Qaagi - Book of Why

Causes

Effects

1p36 deletion syndrome ... a chromosome disordercausessevere intellectual disability

1p36 deletion syndrome ... a disordercausessevere intellectual disability

1p36 deletion syndrome ... a genetic disordercausessevere intellectual disability

a rare abnormality of the braincausingsevere intellectual disability

Down syndromecausessevere intellectual disability

the braincausingsevere intellectual disability

a genetic disordercausessevere intellectual disability

genetic defects(passive) caused bysevere intellectual disability

a copy of the CTNND2 gene in each cell ... this appearsto causesevere intellectual disability

the world 's highest incidence of fumarase deficiency , an extremely rare genetic conditioncausessevere Intellectual disability

a teacherwill discoverdisability ( intellectual

manycauseintellectually disability

mutations in the HIVEP2 gene(passive) is caused byHIVEP2-related intellectual disability

POGZ truncating allelescausesyndromic intellectual disability

POGZ truncating allelescausesyndromic intellectual disability

prenatal gene mutation(passive) may possibly be caused byIntellectual Intellectual disability

V Sutton R. POGZ truncating allelescausesyndromic intellectual disability

a genetic conditioncausingintellectual disability , behavioural

Fragile X syndrome ( FXS ... a neurodevelopmental disordercausesintellectual disability

Fragile x syndrome ( fxs ... a genetic conditioncausesintellectual disability

Fragile X syndrome ... a genetic conditioncausesintellectual disability

" Fragile X Syndrome ... a genetic conditioncausesintellectual disability

fragile X syndrome , a genetic disordercausesintellectual disability

Fragile X syndrome ... genetic disordercan causeintellectual disability

Fragile X syndrome ... a type of genetic disordercan causeintellectual disability

Fragile X syndrome ... a genetic problemcausesintellectual disability

Haploinsufficiency of the E3 ubiquitin - protein ligase gene TRIP12causesintellectual disability

to : Haploinsufficiency of the E3 ubiquitin - protein ligase gene TRIP12causesintellectual disability

Down syndrome , a chromosomal conditioncausesintellectual disability

Fragile X ... a common inherited syndromecausesintellectual disability

Down syndrome ( DS ... a chromosomal disordercausesintellectual disability

Some genetic disorders ... autism such as Fragile X syndromecausesintellectual disability

by the loss of the functional fragile X mental retardation protein ( FMRP(passive) caused byintellectual disability

by loss of function of the fragile X mental retardation protein(passive) caused byintellectual disability

mutations in the NSUN2 genecauseintellectual disability

Mutations in the ARID1B genecan causeintellectual disability

Fragile X syndromecausesintellectual disability

Fragile X syndrome (causesIntellectual Disability

by fragile X syndrome(passive) caused byan intellectual disability

any condition that impairs the development of the brain before birth(passive) can be caused byIntellectual disability

the fetus to nor develop normallycausethe fetus to nor develop normally

in limited functioning inmay resultin limited functioning in

in a cognitive delayresultsin a cognitive delay

to an inability to process compounded by an inability to retain any informationleadingto an inability to process compounded by an inability to retain any information

before the age of 18 and is characterized by significant limitations in both intellectual functioning and in adaptive behavior , which covers many everyday social and practical skillsoriginatesbefore the age of 18 and is characterized by significant limitations in both intellectual functioning and in adaptive behavior , which covers many everyday social and practical skills

such severe educational needs that they can not be accommodated by addressing only one of the impairmentscausessuch severe educational needs that they can not be accommodated by addressing only one of the impairments

before the age of 18originatesbefore the age of 18

a ) limited language abilitycausinga ) limited language ability

to success in inclusive settingleadsto success in inclusive setting

from mutations inresultingfrom mutations in

when the baby does not develop inside the mother properlycan resultwhen the baby does not develop inside the mother properly

when the baby does not develop inside the mother properlycan resultwhen the baby does not develop inside the mother properly

when the fetus does not develop properlycan resultwhen the fetus does not develop properly

when the fetus does not develop properlymay resultwhen the fetus does not develop properly

when the fetus does not develop properlycan resultwhen the fetus does not develop properly

new strengths and abilities , skills and successdiscovernew strengths and abilities , skills and success

if the fetus does not develop properly during pregnancycan also resultif the fetus does not develop properly during pregnancy

during the developmental periodoriginatedduring the developmental period

full , inclusive lives while enriching their communitiesto leadfull , inclusive lives while enriching their communities

before age 22originatedbefore age 22

prior to age 18originatedprior to age 18

before the age of 18originatesbefore the age of 18

before the age of 18originatedbefore the age of 18

before the age of 22 that affects the ability to function in daily lifeoriginatedbefore the age of 22 that affects the ability to function in daily life

before age 22 and which affects their ability to function in daily lifeoriginatedbefore age 22 and which affects their ability to function in daily life

significant limitationscausessignificant limitations

further problemscan causefurther problems

from Down Syndromeresultingfrom Down Syndrome

the problems(passive) caused bythe problems

from a recurrent de novo missense variant in the PACS1 gene ( presultingfrom a recurrent de novo missense variant in the PACS1 gene ( p

meaningful lives in the communityto leadmeaningful lives in the community

when a baby does not develop usually during gestationcan resultwhen a baby does not develop usually during gestation

childrencauseschildren

from recurrentresultingfrom recurrent

to improved inclusive behavioursleadingto improved inclusive behaviours

his familyto leadhis family

symptoms similar to ASDcausingsymptoms similar to ASD

to behaviours similar to those seen in children with autismleadingto behaviours similar to those seen in children with autism

to deathcan leadto death

deathcan causedeath

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