Loading ...
a terminal ECF pathogenesis in whichleadsto secondary systemic macrophage activation syndrome , mononuclear vasculitis , pulmonary edema , respiratory failure and death
the bodyleadingto pulmonary damage , acute lung injury , sepsis , and death
y of ENaC in the lungresultingin premature clearance of lung fluid , airway drying , lung inflammation and perinatal lethality
an inflammatory responsecan causeacute lung injury , including diffuse alveolar hemorrhage and acute respiratory distress syndrome
to initiate regional production of inflammatory cytokines that increase capillary permeabilityleading sequentiallyto pulmonary edema , dyspnea , hypoxia , acute lung injury , and acute respiratory distress syndrome
In mouse , NEDD4 - 2 deletion leads to increased cell surface expression and activity of ENaC in the lungresultingin premature clearance of lung fluid , airway drying , lung inflammation and perinatal lethality
persistent inflammationresultingin airway damage and deteriorating lung function in COPD and bronchiectasis ( 1 , 2
Acute Respiratory Distress Syndrome ( ARDS ) is characterized by diffuse alveolar capillary damageleadingto severe pulmonary edema , respiratory failure and arterial hypoxemia refractory to oxygen therapy
formation of lung cystsleadingto spontaneous pneumothoraces ( lung rupture and collapse ) and progressive loss of pulmonary function
proteinasescausediffuse alveolar and microvascular damage , thus exacerbating acute lung injury
Insufficient PEEPmay resultin alveolar derecruitment , cyclical atelectasis , progressive lung injury , and refractory hypoxemia ( 8)
mechanical stimulation of nasopharynx ( NPh(passive) provoked byCardio - respiratory changes in anaesthetized catduring asphyxia caused by inhalation of CO2 and resuscitation
reactive oxygen speciescontributeto pulmonary inflammation , cytokine dysregulation and acute lung injury
the mechanismsleadingto alveolar epithelial damage in acute lung injury
this isoformcontributesto the pathophysiology of acute lung injury and acute respiratory distress syndrome
finding outis causingacute lung injury and leaving people on respirators
advanced stages of asthmacan leadto lung destruction , ventilation - perfusion mismatch , and arterial hypercapnia
induced lung injuryleadsto loss of alveolar and systemic ventilator - induced lung injury
Prolonged hyperoxiacauseslung injury and respiratory failure secondary to oxidative tissue damage mediated
Mechanical ventilation with high tidal volumes ( VTcausesacute lung injury ( VILI , ventilator - induced lung injury
Mechanical ventilation with high inspiratory pressures and high tidal volumes of > 30 ml / kg ideal body weight in animals with healthy lungscausesinterstitial and alveolar oedema and diffuse lung injury ( ventilation - induced lung injury ( VILI ) ) ; And
Tracheal reintubationpotentially leadsto the airway trauma , aspiration , and acute lung injury
Obesity - induced endoplasmic reticulum stresscauseslung endothelial dysfunction and promotes acute lung injury
activates PMNscontributingto their pulmonary sequestration and mediating lung tissue injury ( 38,39
The mechanismscontributeto pulmonary coagulopathy in acute lung injury
Hemorrhagic shock and resuscitation ( HSR ) is knownto causeinflammatory reactions in the lung parenchyma and acute lung injury
The injectionresultedin pulmonary edema and acute lung injury
Avoid injection of peppermint oilmay resultin pulmonary edema and acute lung injury
a vaporcausesacute lung injury and respiratory failure
a vicious cycleresultingin lung injury to the bronchi and lung parenchyma
that the tidal volume remains constant and peak alveolar pressure increases as the lungs become less compliant ( eg , acute respiratory distress syndrome [ ARDScould resultin alveolar overdistention and acute lung injury
HPV alonecauseslung injury after the pulmonary resection
significantlymay ... contributesignificantly
even withresultseven with
to development and deterioration of OSA in obese personsmay significantly contributeto development and deterioration of OSA in obese persons
in progressive destruction of pulmonary alveoli and chronic respiratory failureresultsin progressive destruction of pulmonary alveoli and chronic respiratory failure
to painleadingto pain
to emphysemaleadsto emphysema
to emphysema andleadsto emphysema and
to a disruption of alveolar - capillary integrity with severe consequences for pulmonary gas exchangeleadsto a disruption of alveolar - capillary integrity with severe consequences for pulmonary gas exchange
in progressive destruction of pulmonary alveoli and chronic respiratory failureresultsin progressive destruction of pulmonary alveoli and chronic respiratory failure
to pulmonary fibrosis J Clin Invest 2001leadingto pulmonary fibrosis J Clin Invest 2001
in the clinical features typically seen in bronchiolitis ( 1resultin the clinical features typically seen in bronchiolitis ( 1
neonatal death and serious long - term morbiditiescan causeneonatal death and serious long - term morbidities
to pulmonary fibrosisleadingto pulmonary fibrosis
in deathcan resultin death
to increased capillary permeability and pulmonary edemaleadsto increased capillary permeability and pulmonary edema
anxiety and panic attackscan causeanxiety and panic attacks
energy shortages in lung cellscan causeenergy shortages in lung cells
to ubiquitination and degradation of growth factor receptors such as Alk5leadsto ubiquitination and degradation of growth factor receptors such as Alk5
from platelet micromay resultfrom platelet micro
to multiorgan failure ( 30 , 52can leadto multiorgan failure ( 30 , 52
in presultsin p
from platelet micro aggregates or donor antibodies against recipient antigensmay resultfrom platelet micro aggregates or donor antibodies against recipient antigens
long?term impairment of alveolar developmentcauseslong?term impairment of alveolar development
to impaired endocytosis which leads to ubiquitination and degradation of growth factor receptors such as Alk5leadsto impaired endocytosis which leads to ubiquitination and degradation of growth factor receptors such as Alk5
in protein - rich lung edema , influx of proinflammatory leukocytes , and intractable hypoxemiaresultsin protein - rich lung edema , influx of proinflammatory leukocytes , and intractable hypoxemia
long - term impairment of alveolar development : A new rat model of BPDcauseslong - term impairment of alveolar development : A new rat model of BPD
to the expanding burden of critical illness within our ICUscontribute substantiallyto the expanding burden of critical illness within our ICUs