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Qaagi - Book of Why

Causes

Effects

to breathe properlyto preventhypercapnia ( CO2 retention ) and pulmonary barotraumas ( lung expansion injuries

The higher ΔPCO2 seen initially appearedto resultfrom impaired CO2 elimination secondary to critical reductions in systemic and pulmonary blood flow

High levels of H2S can be directly toxic to the lungs ,causingacute lung injury and/or triggering apnea through regulation of CO2 receptors.17

Vascular leakage was previously suspectedto contributeto acute lung injury and respiratory impairment after esophagectomy27,28,29,30

cannabis useresultingin acute lung injury and diffuse alveolar hemorrhage

These metabolitesmight contributeto coagulopathies of trauma and neutrophil priming driving acute lung injury

that the tidal volume remains constant and peak alveolar pressure increases as the lungs become less compliant ( eg , acute respiratory distress syndrome [ ARDScould resultin alveolar overdistention and acute lung injury

An important disadvantage of this mode ... eg , acute respiratory distress syndrome [ ARDScould resultin alveolar overdistention and acute lung injury

new molecular mechanismsleadingto arterial ( atherosclerosis ) and pulmonary ( acute lung injury

prophylactic SODwould preventacute lung injury caused by hyperoxia and hyperventilation

to asthmalike symptomsleadto asthmalike symptoms

to a sudden decrease in the BIS and increase in PetCO2 in anesthetized patients [ 4can leadto a sudden decrease in the BIS and increase in PetCO2 in anesthetized patients [ 4

this severe pulmonary edema(passive) was caused bythis severe pulmonary edema

to rapid decline of respiratory function and deathmay leadto rapid decline of respiratory function and death

Chronic respiratory failure(passive) is caused byChronic respiratory failure

in pulmonary vascular diseaseresultsin pulmonary vascular disease

in hypoxemia , tachypnea , dyspnea , and death in about 50 % of affectedresultin hypoxemia , tachypnea , dyspnea , and death in about 50 % of affected

from endothelial cell damageoriginatingfrom endothelial cell damage

to a disruption of alveolar - capillary integrity with severe consequences for pulmonary gas exchangeleadsto a disruption of alveolar - capillary integrity with severe consequences for pulmonary gas exchange

to right ventricular failurecan ... leadto right ventricular failure

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