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protein kinasecausesphosphorylation and inactivation of myosin light - chain kinase leading to inactivation of Ca2
Relaxation of the myometrium ... are increasedleadingto activation of protein kinases , which phosphorylate myosin light - chain kinase
the activation of cGMP - specific protein kinaseresultingin the phosphorylation and inactivation of myosin light - chain kinase
Ca2+]ileadsto the activation of calmodulin - dependent myosin light chain kinase ( MYLK
Uterine smooth muscle contraction ... intracellular free calcium ( [ Ca2+]ileadsto the activation of calmodulin - dependent myosin light chain kinase ( MYLK
Uterine smooth muscle contraction ... Ca2+]ileadsto the activation of calmodulin - dependent myosin light chain kinase ( MYLK
a MAPK ( mitogen - activated protein kinase ) pathwayresultedin the activation of myosin light chain kinase
The decrease in intracellular calcium levelsleadsto an inhibition of myosin light - chain kinase
Rho - kinase pathwayleadingto inhibition of the myosin light chain phosphatase
pathwaysleadingto inhibition of myosin light - chain phosphatase
cyclic gmp levelscausesdephosphorylation of myosin light chain kinase(mlck
MLCK ) activityleadingto phosphorylation of myosin light chains ( MLC
actin assembly ... agentsinfluencemicrotubules and myosin light chain kinase
which activate Rho kinaseleadingto myosin light - chain phosphorylation
multiple mechanismsresultin phosphorylation of myosin light chain
The resulting Ca2+transients activate calmodulin ( CaMleadingto the stimulation of myosin light chain kinase ( MLCK
Activation of the RAS / MAPK / ERK signaling pathwayalso resultsin myosin light chain phosphorylation
that biphosphorolic calciumcausesa phosphorylation of the myosin light chain
ECM densityinfluencesmyosin light chain phosphorylation
the Rho effector protein ROCK I ,contributesto phosphorylation of myosin light - chains
allows access of the protein substrate to the active site of the enzymeresultingin phosphorylation of the myosin light chains
This complexpromptsthe kinase on the myosin light chain
Deficiency in myosincauseslight - chain phosphorylation
signalingleadingto myosin light chain kinase
a positive inotropic effect on cardiomyocytes of animal models with cardiac insufficiency ... 5-HT4 ,leadto the phosphorylation of the light chain of myosin
Discoveries of Genetic Mutations Discovery of Inactivating Mutations in the genediscoveredBranched Chain Ketoacid Dehydrogenase Kinase Meguid
to force generationleadingto force generation
increased myosin activity and contractioncausesincreased myosin activity and contraction
to smooth muscle relaxationleadsto smooth muscle relaxation
to the start of the necroptosis process ( Newton and Manning , 2016leadsto the start of the necroptosis process ( Newton and Manning , 2016
vascular smooth muscle contractioncausesvascular smooth muscle contraction
to phosphorylation of the MLC ( myosin regulatory light chainleadingto phosphorylation of the MLC ( myosin regulatory light chain
to phosphorylation of the MLCleadingto phosphorylation of the MLC
to smooth muscle relaxation andleadsto smooth muscle relaxation and
contractioncausescontraction
to smooth muscleleadsto smooth muscle
to an activation of the contractile machineryleadingto an activation of the contractile machinery
to phosphorylation of the MLC ( myosin regulatory light chainleadingto phosphorylation of the MLC ( myosin regulatory light chain
to smooth muscle relaxation and bronchodilation.[1leadsto smooth muscle relaxation and bronchodilation.[1
to smooth muscle relaxation and bronchodilation.[2leadsto smooth muscle relaxation and bronchodilation.[2
to smooth muscle relaxation and bronchodilationleadsto smooth muscle relaxation and bronchodilation
howevermay ... resulthowever
to smooth muscle relaxation and bronchodilationleadsto smooth muscle relaxation and bronchodilation
to smooth muscle relaxation and vasodilationleadsto smooth muscle relaxation and vasodilation
to contraction of the cortical actin cytoskeletonleadingto contraction of the cortical actin cytoskeleton
to actin - myosin association and cell contractionleadingto actin - myosin association and cell contraction
in increased MLCK activity and MLC phosphorylationresultingin increased MLCK activity and MLC phosphorylation
CA - MLCK ) expression within intestinal epithelial cellscausesCA - MLCK ) expression within intestinal epithelial cells
to loss of cellular contractionleadingto loss of cellular contraction
to contraction of the actin - myosin ringleadsto contraction of the actin - myosin ring
decreased smooth muscle contractioncausesdecreased smooth muscle contraction
to actin - myosin assemblyleadingto actin - myosin assembly
smooth muscle contractioncausingsmooth muscle contraction
to relaxation of the smooth muscle surrounding the DAleadingto relaxation of the smooth muscle surrounding the DA
to the formation of contractile actomyosinleadto the formation of contractile actomyosin
in vasorelaxationresultingin vasorelaxation
to contraction of the cortical actin cytoskeletonleadingto contraction of the cortical actin cytoskeleton
in vascular smooth musclecausingin vascular smooth muscle
SM contractioncausingSM contraction
to its co - operative activation by calmodulinleadingto its co - operative activation by calmodulin
CEC apoptosis(passive) caused byCEC apoptosis
to decreased myosin phosphorylation and a decrease in contractile forceleadsto decreased myosin phosphorylation and a decrease in contractile force
phosphorylation of myosincausingphosphorylation of myosin
to increased MLC phosphorylationleadingto increased MLC phosphorylation
to activation of the actin / myosin motor and cell migrationleadingto activation of the actin / myosin motor and cell migration
to vascular smooth muscle cellleadto vascular smooth muscle cell