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Qaagi - Book of Why

Causes

Effects

cardiac tissue damage(passive) caused bypacing threshold increase

cardiac tissue damageAbstractFulltextPDFWeb of Science(passive) caused bypacing threshold increase

cardiac tissue damageGap junction alterations in human cardiac diseaseConnexin 43 and ischemic preconditioningAcute ischemia - induced gap junctional uncoupling and arrhythmogenesisGap junction - mediated spread of cell injury and death during myocardial ischemia - reperfusionPrimary and Secondary(passive) caused bypacing threshold increase

6 LVleadswith increased pacing threshold

electrodespotentially leadingto pacing threshold increases

the fatty tissue layer outside the myocardium(passive) caused bythe increased pacing threshold

a standoffwould causean increase in the pacing threshold

eHealthMe ( http://www.eHealthMe.com(passive) created byPacing Threshold Increased

Intake of Dronedaron(passive) Caused byIncreased Ventricular Pacing Threshold

it to use more energy to detect my heartcausingit to use more energy to detect my heart

in loss of capture and ineffective pacing therapycan resultin loss of capture and ineffective pacing therapy

sensing malfunctions and failure to capturemay also causesensing malfunctions and failure to capture

to non- capturecan leadto non- capture

from strategic slowingresultingfrom strategic slowing

in loss of capture that can be corrected by hormonal repletion.9,10resultingin loss of capture that can be corrected by hormonal repletion.9,10

to early battery depletion and frequent lead fracturesleadingto early battery depletion and frequent lead fractures

to ventricular tachycardia or fibrillationleadingto ventricular tachycardia or fibrillation

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