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Within the first stage , iron requirement exceeds intakecausingdepletion of bone marrow iron stores
neoplasms secreting erythropoietin Treatment to relieve hypoxia(passive) Could be caused byincreased formation of RBCs in bone marrow
In the first stage , body iron requirement exceeds iron intakecausingprogressive depletion of bone marrow iron stores
by which the mutations impair iron release from macrophages ,resultingin inadequate iron supply to the bone marrow
In the 11 st stage iron requirement exceeds intakecausingprogressive depletion in bone marrow iron stores
Chronic blood lossleadsto depletion of bone marrow iron stores over time
Injection of mice with cell - free conditioned medium derived from hypoxic mammary tumor cellsresultedin increased bone marrow
that suppress hepcidin production in the liverresultingin increased iron supply to the bone marrow
to increased red blood cell production and higher hemoglobinleadsto increased red blood cell production and higher hemoglobin
chances of pernicious anemiato preventchances of pernicious anemia
a radiolucent radiographic defectcreatesa radiolucent radiographic defect
to a disproportionate increase in osteoclast formationcontributesto a disproportionate increase in osteoclast formation
in reduced availability of iron for erythropoiesisresultingin reduced availability of iron for erythropoiesis
to increased RBC massleadsto increased RBC mass
Expansion of RBC mass(passive) is caused byExpansion of RBC mass
to higher blood viscositycan leadto higher blood viscosity
Disease(passive) caused byDisease
Hemoglobin , the oxygen - transporting protein found in red blood cells(passive) is createdHemoglobin , the oxygen - transporting protein found in red blood cells