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Qaagi - Book of Why

Causes

Effects

Drugs such as amiodarone and glucocorticoidscan also causeincreased RT3 levels

the different factorscausingincreased FGF23 levels

a conditioncan causeincreased levels

The problemmay causeincreased levels

decreased cholesterol also binds to the LDL receptorcausingincreased levels

the drug which > >causesincreased levels

amplification of YES1 , one member of the SFKs ... and further led to EGFR - TKIs resistance [ 25(passive) were caused byincreased pSFKs levels

or not exposure to media violencecausesincreased levels

Gilbert ’s , Rotor ’s , Dubin - Johnson , Crigler - Najjar syndromesmay also causeincreased levels

acid ( 5-ASA ) drugs may decrease the TPMT activitythereby causingincreased 6-TGN levels

Polyglutamation also affects folate and recycled DHF , thereforecausingincreased intracellular levels

Strenuous exercisemay causeincreased levels

Long - term kidney diseasemay ... resultIncreased troponin levels

two conditionscan causeincreased procalcitonin levels

Other factors that might impact PCOS ... excess insulincausesincreased androgen levels

A number of factors ... TSH results.[3 ] Factorscan causeincreased levels

kidney damage , certain drugs , low fluid intake , intestinal bleeding , exercise , heart failure or decreased digestive enzyme production by the pancreas(passive) can be caused byIncreased levels

Medication such as Aldomet and gentamycincan causeincreased levels

The majority of L - arginine ... process ed into creatineleadsincreased homocysteine levels

exposure to violencecauseincreased levels

conditions in other parts of the bodymay causeincreased troponin levels

two factors : the experience of stress , and failure to adequately breakdown the noradrenalin into a form that can be excreted(passive) can be caused byIncreased levels of noradrenalin

The use of oral contraceptives and estrogencan also causeincreased levels

Infection or inflammation and surgery to the prostatecan also causeincreased levels

Chronic diseases and inflammatory conditionscan causeincreased monocyte levels

overexpression of certain genes other than IPTcausesincreased cytokinin levels

stress , poor diet , smoking , heavy metal toxicity , elevated blood fats , medications , and lack of vitamins B12 , vitamins B6 , folic Acid and excess iron(passive) maybe caused byIncreased homocysteine levels

smoking nonnicotine cigarettes upon exercise - induced angina(passive) caused byincreased carboxyhemoglobin levels

many conditions , including cancer , heart attack(passive) are caused byIncreased levels

The estrogen content of organic bathing peats and its therapeutic significanceresultIncreased hepcidin levels

chronic cardiac disorders from acute cardiac conditions such as AMI(passive) caused byincreased levels

This has also been shown in humans , where patients with fatty liver had a susceptibility to higher gut permeabilitypossibly causingincreased endotoxin levels

any trauma , burns , major illnesses , cancer , psoriasis , diabetes , auto - immune diseases , and even exercisecan causeincreased IL-6 levels

values used in diagnosis of acute coronary syndrome and myocardial infarct and the ability to distinguish these conditions from other comorbiditiescauseincreased troponin levels

C , the overexpression of constitutively active AKT1 ( Myr - AKT1 ) in the Pten / Trp53–recombined MEF cellspromptsincreased PCNA levels

that irisin increases in adaptation to resistance exercise in rats , and its production leads to the following sequence : resistance exercise stimulates FNCD5 gene expressioncausingincreased irisin levels

high cyanobacterial cell densitiescauseincreased microcystin levels

Improvementcreatingincreased levels

a higher intake of fatty acids in food or by the conversion of LA to AA(passive) are caused byIncreased levels

sildenafil open up blood vessels and improve blood flow(passive) caused byIncreased levels of cGMP

to a significant attenuation of repair which may reflect the previously observed reduced capacity for epithelial repair of asthmatic versus control cells in cell culture.36 Supernatant uPAleadto a significant attenuation of repair which may reflect the previously observed reduced capacity for epithelial repair of asthmatic versus control cells in cell culture.36 Supernatant uPA

in elevated level of Class 2 secretion substrates and additionally in more potential secretion systemsresultin elevated level of Class 2 secretion substrates and additionally in more potential secretion systems

from innate immune activationresultfrom innate immune activation

to increased circulating total thyroid hormone levels as measured by protein- bound iodine ( PBI ) , T4 levels ( by column or by radioimmunoassay ) , or T3 levels by radioimmunoassayleadingto increased circulating total thyroid hormone levels as measured by protein- bound iodine ( PBI ) , T4 levels ( by column or by radioimmunoassay ) , or T3 levels by radioimmunoassay

in Altered Distribution of Phosphorylated FAK ARPE-19 and ARPE-19 / EMP2Resultedin Altered Distribution of Phosphorylated FAK ARPE-19 and ARPE-19 / EMP2

to decreased expression of the sodium - phosphate co - transporters in the proximal tubules , reduced renal phosphate reabsorption , increased excretion by the kidneys , and low serum phosphate concentrationleadto decreased expression of the sodium - phosphate co - transporters in the proximal tubules , reduced renal phosphate reabsorption , increased excretion by the kidneys , and low serum phosphate concentration

vasoconstriction and thrombosis ( platelet aggregation ) that can trigger atherosclerosis , myocardial infarction , ischemic stroke , and hypertensioncausevasoconstriction and thrombosis ( platelet aggregation ) that can trigger atherosclerosis , myocardial infarction , ischemic stroke , and hypertension

to oxidative stress in Hif2α+/− mice by activation of Nox2 expressioncontributeto oxidative stress in Hif2α+/− mice by activation of Nox2 expression

in serious cardiac arrhythmiasresultingin serious cardiac arrhythmias

in an enhanced activation of procarcinogens to carcinogens [ 17 ... and induction of oxidative stress [ 18resultin an enhanced activation of procarcinogens to carcinogens [ 17 ... and induction of oxidative stress [ 18

to retention of intron 1 in the 5′ UTR ( Additional file   1 : Figure S13Eledto retention of intron 1 in the 5′ UTR ( Additional file   1 : Figure S13E

to proliferation of neutrophils , which , in turn , generate Superoxide molecules that mediate inflammation and tissue destruction.15leadto proliferation of neutrophils , which , in turn , generate Superoxide molecules that mediate inflammation and tissue destruction.15

to recruitment of neutrophils to the site of inflammation and cause oxidative stress , leading to tissue damage and thus also to exposure of nerve endings to nociceptive mediatorscould leadto recruitment of neutrophils to the site of inflammation and cause oxidative stress , leading to tissue damage and thus also to exposure of nerve endings to nociceptive mediators

SOC1 activation , which in turn contributes to TSF up - regulationtriggerSOC1 activation , which in turn contributes to TSF up - regulation

to the direct activation of phosphodiesterase 5 , which in turn degrades cGMP more rapidlyleadto the direct activation of phosphodiesterase 5 , which in turn degrades cGMP more rapidly

in myevening cravings of starchy , sugary junk foodresultin myevening cravings of starchy , sugary junk food

an increase in the secretion rate of aldosterone from the adrenal cortex , thereby raising the extracellular fluid concentation of this hormonecausean increase in the secretion rate of aldosterone from the adrenal cortex , thereby raising the extracellular fluid concentation of this hormone

in more pronounced colorresultin more pronounced color

to increased ( 1 ) supply of oxygen ( more bloodleadto increased ( 1 ) supply of oxygen ( more blood

to an enhancement in active RhoA levels , which results in deficits in excitatory synapse formationleadto an enhancement in active RhoA levels , which results in deficits in excitatory synapse formation

SIgA generation ... as demonstrated in mice under repeated restraint stress [ 21 , 25may ... influenceSIgA generation ... as demonstrated in mice under repeated restraint stress [ 21 , 25

to increased hemoglobin levels and red blood cell massleadingto increased hemoglobin levels and red blood cell mass

to increased serotonin , which validates some claims from ageing men about experiencing improved mood and perceived quality of life after two - day cleansesleadsto increased serotonin , which validates some claims from ageing men about experiencing improved mood and perceived quality of life after two - day cleanses

from administration of sildenafilresultingfrom administration of sildenafil

to an increase in vascular permeability and edema formationleadto an increase in vascular permeability and edema formation

to improved performance in both trained and untrained individuals [ 6leadsto improved performance in both trained and untrained individuals [ 6

from the drug′s ability to block kininase IIresultingfrom the drug′s ability to block kininase II

to transcriptional activation of several ER chaperonesleadto transcriptional activation of several ER chaperones

in a slight increase in NF - κB transcriptional activity ... supporting further the hypothesis that TfR1 modulates IKK – NF - κB activityresultin a slight increase in NF - κB transcriptional activity ... supporting further the hypothesis that TfR1 modulates IKK – NF - κB activity

in strengthened MT – cortex interactions preferentially at the bud cortexresultin strengthened MT – cortex interactions preferentially at the bud cortex

to decreased production of DHT in male fetus & feminized external genitalia at birth w/ virilization at pubertyLeadsto decreased production of DHT in male fetus & feminized external genitalia at birth w/ virilization at puberty

in altered monolayer permeabilityresultin altered monolayer permeability

to increases in the lipid levels ( Table 1 ... Supplementary Table 3 and Supplementary Figure 5ledto increases in the lipid levels ( Table 1 ... Supplementary Table 3 and Supplementary Figure 5

to the enhanced bactericidal capacity of myeloid cells followingcontributeto the enhanced bactericidal capacity of myeloid cells following

after stimulation of PBMCs by PSKresultafter stimulation of PBMCs by PSK

from sGCresultingfrom sGC

to the over - activation of the pro - inflammatory phenotype of monocytesmay contributeto the over - activation of the pro - inflammatory phenotype of monocytes

in broad cellular benefits and reduced incidences of cancer , diabetes , Alzheimer ’s , and cardiovascular diseaseresultin broad cellular benefits and reduced incidences of cancer , diabetes , Alzheimer ’s , and cardiovascular disease

in enhanced substrate delivery to the working muscles ( Woods et al .resultingin enhanced substrate delivery to the working muscles ( Woods et al .

to angioedema - related symptomsleadsto angioedema - related symptoms

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