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The insight gained from simulation results can then be usedto designin vivo and in vitro experiments
Dataresultingfrom the in vivo and in vitro experiments
YY and NHcontributedto the in vivo and in vitro experiments
RB , LH , KH , MA , JC and JGdesignedin vivo and in vitro experiments
ableto causeneurotoxicity in vivo and in vitro
Data and ResultsledIn vitro and in vivo sunitinib treatment
Our previous work indicatedcan causeneurotoxicity both in vivo and in vitro
Demonstrated abilityto designin vitro and in vivo systems
factorsmay influencein vitro and in vivo results
the mechanismis ... been discoveredin vitro and in vivo studies
Factorsinfluencingin vivo and in vitro micrografting of Sandalwood
Following this , we discuss the effects of LDIR on stem cellsdiscoveredthrough in vitro and in vivo studies
Blockage of ASCT2 activity with V-9302 ... increased oxidative stresscontributedto antitumor responses in vitro and in vivo
any activity knownto be causedin vivo or in vitro
is shownto causein vivo and in vitro
Increased secretion of VEGF - A , as was reported beforeleadsto angiogenesis in vitro and in vivo
the damagecausedin vivo and in vitro
pathwayleadsto in vitro and in vivo angiogenesis
down - regulationinfluencesneuronal arborization in vitro and in vivo
We originally set outto designin vitro and in vivo assays
vessel - residing endothelial stem / progenitor cellscontributingto angiogenesis in vitro and in vivo
a key role in ALCL lymphomagenesis ... has been shownto causelymphoid malignancy in vitro and in vivo
In the coronary circulation , these compounds have been shownto causevasorelaxation both in vitro and in vivo
cellsoriginatingfrom MSPs both in vitro and in vivo
Such mutationspromptin vitro and in vivo tumorigenicity
that have been shownto causein vitro and in vivo
Dataresultedfrom in vitro and in vivo
Vasicinone , the auto - oxidation product of vasicine , has been reportedto causeboth in vitro and in vivo
some preclinical studiesledin - vitro and in - vivo
which also has been shownto influencein vitro and in vivo
The high clearance valuesmay causein vitro - in vivo discorrelation
many other promising targetsare ... discoveredin vitro and in vivo
DC maturation has also been shownto resultin vitro and in vivo
in articles in peer reviewed journalshas resultedin articles in peer reviewed journals
The study(passive) was designedThe study
to a hyperpigmented retinal phenotype [ 21,24,25leadsto a hyperpigmented retinal phenotype [ 21,24,25
studieshave ledstudies
to address the unique formulation requirements of companion animalsdesignedto address the unique formulation requirements of companion animals
the damage(passive) caused bythe damage
studiesdiscoveredstudies
in isolation and identification of several different bioactive moleculesresultingin isolation and identification of several different bioactive molecules
in multi - organ damage to the lungs , the heart , the liver , the kidney , and the nervous system , as well as the reproductive and immune systems5,6can resultin multi - organ damage to the lungs , the heart , the liver , the kidney , and the nervous system , as well as the reproductive and immune systems5,6
to a decrease in their proliferationleadingto a decrease in their proliferation
translational therapywill ... causetranslational therapy
to translational therapywill ... leadto translational therapy
in arrest of cells in the G2 and M phase of the cell cycleresultingin arrest of cells in the G2 and M phase of the cell cycle
any activity known(passive) to be causedany activity known
neuroapoptosis(passive) provoked byneuroapoptosis
Future studies(passive) will be designedFuture studies
the oxidative DNA damage(passive) caused bythe oxidative DNA damage
solid transcriptional alteration in atrial cardiomyocytes , which are partially reversible by Irbesartancausessolid transcriptional alteration in atrial cardiomyocytes , which are partially reversible by Irbesartan
the effect of targeted therapies ... while MSCs , though found to lower the levels of IL-10 in vitro , appeared to display a more complex mechanism of action which may be of benefit in blocking the disease - specific pathogenic effector arm and restoring immune toleranceinfluencethe effect of targeted therapies ... while MSCs , though found to lower the levels of IL-10 in vitro , appeared to display a more complex mechanism of action which may be of benefit in blocking the disease - specific pathogenic effector arm and restoring immune tolerance
to the clearance of Acontributedto the clearance of A
high - throughput screen identifies treatmentleadshigh - throughput screen identifies treatment
to subsequent hyperphosphorylation of 4E - BP1 at T70 and S65 by LRRK2 or other protein kinasesleadingto subsequent hyperphosphorylation of 4E - BP1 at T70 and S65 by LRRK2 or other protein kinases
to endothelial dysfunction and vascular diseasescontributesto endothelial dysfunction and vascular diseases
in decreases in Homer1 promoter H3K9 methylation in amygdala cells but increases in Homer1 promoter H3 acetylation in hippocampal cellsresultin decreases in Homer1 promoter H3K9 methylation in amygdala cells but increases in Homer1 promoter H3 acetylation in hippocampal cells
in somatic Cell hybridizationresultsin somatic Cell hybridization
many other promising targets(passive) are ... discoveredmany other promising targets
to DNA damage , lipid peroxidation , and protein carbonylationledto DNA damage , lipid peroxidation , and protein carbonylation
virus dissemination and pathogenesisinfluencingvirus dissemination and pathogenesis
in cell cycle S - phase arrestresultedin cell cycle S - phase arrest
proliferation rate , migration , tumour growth and metastasiscan influenceproliferation rate , migration , tumour growth and metastasis