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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

the report ... that are expectedto influencethe development rate of the Oral Cholera Vaccine market

Dr. Clemensledthe first efficacy trial of an oral vaccine against cholera

the potentialto causeresult in primary rotavirus vaccine failure in developing countries

the studywas ... designedpowered to assess vaccine efficacy on the disease

the mechanismsmay contributeto the poor response of infants in developing countries to oral vaccines

an important factorcontributingto the reduced performance of current live oral rotavirus vaccines in developing countries

the factorscontributingto oral vaccine underperformance in children from developing countries

interventionsdesignedto increase oral vaccine efficacy or immunogenicity

innate and adaptive immune systemscould leadto effective approaches in vaccine development

the probable factorsleadto lower responses in vaccine recipients in developing countries

the probable factors ... leadto lower responses in vaccine recipients in developing countries

Tropical enteropathy , which is associated with intestinal inflammation , decreased absorption and increased permeabilitymay contribute substantiallyto oral vaccine failure in developing country settings

this discoverywill leadto the development of an oral vaccine against chlamydia

by Yersinia ruckeri ( Hagerman strain ) in rainbow trout ( Oncorhynchus mykiss(passive) caused byan inactivated , oral vaccine against Enteric Redmouth Disease

Yersinia ruckeri ( Hagerman strain ) in rainbow trout ( Oncorhynchus mykiss(passive) caused byan inactivated , oral vaccine against Enteric Redmouth Disease

Other factorscould be contributingto the lower efficacy of rotavirus vaccines in developing countries

factorscontributingto low vaccination rates in developing countries

barriersleadingto low HPV vaccine uptake in developing countries

Attempts to isolate " host - protective " antigens in parasitic infectionsmay leadto effective vaccine development

a discoverycontributedto the development of an oral vaccine

an effortdesignedto speed delivery of vaccines to developing countries

the gut microbiotamay contributeto differences in oral vaccine efficacy

an important geographic contextual variableinfluencesoral cholera vaccine effectiveness

The results of his effortsledto the use of the oral vaccine

Sir Frank Macfarlane Burnet research into the polio viruscontributedto the development of the oral vaccine

the hypothesis ... the differential presence of immune - stimulating intestinal microbesinfluencesoral rotavirus vaccine efficacy in infants

The primary initial focus of the institute isto contributeto the development of an effective AIDS vaccine

the factorsinfluencingeffectiveness of oral rotavirus vaccines

The viruses used ... the same specimenhas resultedin the oral polio vaccine ( OPV

Albert Sabindiscoversan oral vaccine for polio

the factorscontributingto oral vaccine underperformance

These findingsmay contributeto the development of an effective vaccine against schistosomiasis

their scientistshad discoveredin the oral polio vaccine

vitamin A and vitamin D supplementation studieshave been designedto improve vaccine efficacy

the same specimenhas resultedin the oral polio vaccine ( OPV

The trialwasn?t designedto assess efficacy of the vaccine

lung architecturecontributeto therapeutic vaccine efficacy in the

one strategymay leadto the development of an effective vaccine against HIV

the discoverymight leadto the development of an effective HIV vaccine

an immune responsewill ... leadto development of an effective HIV-1 vaccine

paralysisdoes ... causeparalysis

VAPPcan causeVAPP

VAPP ... to inactivated polio vaccine , which can notcan causeVAPP ... to inactivated polio vaccine , which can not

a case in 2005causeda case in 2005

trials of future tuberculosis vaccinesdesigntrials of future tuberculosis vaccines

in kidscausingin kids

to interventions that have saved millions of lives , especially in Africahas ledto interventions that have saved millions of lives , especially in Africa

the study(passive) was ... designedthe study

poliois causingpolio

and implementation of a large scale complex network of millions of health workers , public institutions and target population living in diverse social , economic , cultural , and geographical conditionsto designand implementation of a large scale complex network of millions of health workers , public institutions and target population living in diverse social , economic , cultural , and geographical conditions

in deathcan resultin death

to the spread of HIVCould ... have contributedto the spread of HIV

in various estimates of clinical effectivenesshave resultedin various estimates of clinical effectiveness

a decade ago and just take the code for making that fragmentwas inventeda decade ago and just take the code for making that fragment

increasing economic lossesis causingincreasing economic losses

to worldto contributeto world

diarrhoea , a disease that kills almost 100,000 children in India annuallycausesdiarrhoea , a disease that kills almost 100,000 children in India annually

to mounting economic losseswas leadingto mounting economic losses

The network(passive) was designedThe network

peoplemay have influencedpeople

in a reduction of invasive Hib disease ratescan resultin a reduction of invasive Hib disease rates

likelycontributeslikely

in a reduction of invasive Hib disease rates by over 80 %can resultin a reduction of invasive Hib disease rates by over 80 %

all polio outbreaks since 1961(passive) were caused byall polio outbreaks since 1961

all polio outbreaks since 1961(passive) were causedall polio outbreaks since 1961

and launched in 2002 with the goal of generating policy - relevant data to enable expanded use of Vi vaccine in public health programwas designedand launched in 2002 with the goal of generating policy - relevant data to enable expanded use of Vi vaccine in public health program

to significantly lower levels of cervical cancerhas ledto significantly lower levels of cervical cancer

vomiting and diarrheacausevomiting and diarrhea

to shortages of Vaccinehas ledto shortages of Vaccine

in higher infant mortality rateshas resultedin higher infant mortality rates

in relatively low population immunity estimates in southern districts ... Figure 3resultsin relatively low population immunity estimates in southern districts ... Figure 3

in more efficiency of these productsmay resultin more efficiency of these products

vomiting and diarrhea ... and may help to remedy gastroenteritis ( also called " stomach flucausevomiting and diarrhea ... and may help to remedy gastroenteritis ( also called " stomach flu

to the lossesis contributingto the losses

more than 500,000 deaths per yearcausesmore than 500,000 deaths per year

in channelingresultingin channeling

to a huge decrease in childhood deathshas ledto a huge decrease in childhood deaths

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Smart Reasoning:

C&E

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