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Qaagi - Book of Why

Causes

Effects

Benaroya Research Institute receives 7-year awardto leadImmune Tolerance Network7

orderto createan immune tolerance

immune response ... regulatory T - cells ( Tregsresultsin immune tolerance

the dendritic cells ’ abilityto createimmune tolerance

2358757114.Intravenous transfer of apoptotic cell - treated dendritic cellsleadsto immune tolerance

The ITN ... type 1 diabetes and solid organ transplantationleadto immune tolerance

experimental autoimmune encephalomyelitis Intravenous transfer of apoptotic cell - treated dendritic cellsleadsto immune tolerance

this signalling ... regulatory T cellsleadsto immune tolerance

T - cell response ... patientsleadsto immune tolerance

cells and processescontributingto immune tolerance

The immune tolerance network ... type 1 diabetes and solid organ transplantationleadto immune tolerance

Andrew Mellor , PhD , received a $ 1.5 M , 4-year R01 grant from NIAID / NIH for “ Engineering DNA nanoparticlesto createimmune tolerance

relatively high Ley on normal cells(passive) caused byimmune - tolerance

LPS - induced tolerogenic dendritic cellsmay causeimmune tolerance

the focus ... the tissue factorscontributeto immune tolerance

CD4+CD25+Foxp3 + regulatory T cellsleadingto immune tolerance

Eduardo ’s future research ... processmight resultin immune tolerance

melanoma interacting with the liver microenvironment Main applicants(passive) caused bysystemic immune tolerance

immune system damage(passive) caused bythe body immune tolerance

alterations in the immune systemleadto immune tolerance

CrossRefPubMedPubMedCentral Zhou F , Lauretti E , di Meco A , Ciric B , Gonnella P , Zhang GX , Rostami A. Intravenous transfer of apoptotic cell - treated dendritic cellsleadsto immune tolerance

Dr. Hirani gets amazing results with LDIto createimmune tolerance

Presentation ] 線溶系からDICを捉える2009 [ Presentation ] Intrathymic administration of Factor VIIIresultsin immune tolerance

The Immune Tolerance Network ... the development of therapeutic approaches for asthma and allergy , autoimmune diseases , type 1 diabetes and solid organ transplantationleadto immune tolerance

the PD1 ... the T cellsleadsto immune tolerance

injected cellscan causeimmune tolerance

the molecular mechanismscontributingtowards immune tolerance

The Immune Tolerance Network ( ITN ... the development of therapeutic approaches for asthma and allergy , autoimmune diseases , type 1 diabetes and solid organ transplantationleadto immune tolerance

the Immune Tolerance Network ( ITN ) , a collaborative network for clinical research ... therapeutic approachesleadto immune tolerance

a new , indirect effector mechanism by which IL-35-responding antigen - presenting cellscontributeto immune tolerance

cialis work cells ... most likelyto resultin immune tolerance

recombinant Echinococcus granulosus(passive) caused byunderlying immune tolerance

which direct the natural killer cells not to attack the cancer cellsresultingin immune tolerance

What two processescontributeto immune tolerance

What opttions processescontributeto immune tolerance

Immune Checkpoint Inhibitors ( 20 ) Indoleamine 2,3-dioxygenase 1 ( IDO1 ) is a critical regulator of T cell functioncontributingto immune tolerance

failure of the embryoto createimmune tolerance

University Immune tolerance induced by intravenous transfer of immature dendritic cells via up - regulating numbers of suppressive IL-10 + IFN - γ+-producing CD4 + T cells Intravenous transfer of apoptotic cell - treated dendritic cellsleadsto immune tolerance

environmental factors in genetically susceptible individuals(passive) triggered byimmune tolerance

Long - term presentation of HBsAg in the serum of patients with chronic HBV infectionmay leadto immune tolerance

to autoimmunity mechanismleadingto autoimmunity mechanism

to secondary autoimmunityleadingto secondary autoimmunity

to autoimmunity ( 61leadsto autoimmunity ( 61

and protect from autoimmunityto preventand protect from autoimmunity

in autoimmunity of some kindwould ... resultin autoimmunity of some kind

to systemic autoimmunityleadingto systemic autoimmunity

the resurgence of autoimmunity [ 1will preventthe resurgence of autoimmunity [ 1

to autoimmunity in susceptible individualspotentially leadingto autoimmunity in susceptible individuals

to reduced immune responses and protection from autoimmunityleadingto reduced immune responses and protection from autoimmunity

the immune system from attacking them.[43 ] Epigeneticpreventsthe immune system from attacking them.[43 ] Epigenetic

in autoimmune responsescould ... resultin autoimmune responses

from a number of causes , including : { { } } Prior contact with the same antigen in fetal life or the newborn period when the immune system was not yet maturecan resultfrom a number of causes , including : { { } } Prior contact with the same antigen in fetal life or the newborn period when the immune system was not yet mature

islet autoimmunity HIP = hybrid insulin peptidetriggersislet autoimmunity HIP = hybrid insulin peptide

the response to later LMB-100 challengepreventedthe response to later LMB-100 challenge

inflammation against normal components of the body[citationpreventsinflammation against normal components of the body[citation

inflammation against normal components of the body.depreventsinflammation against normal components of the body.de

to an overt immune responseleadingto an overt immune response

excessive immune cell activity that can lead to tissue destruction and autoimmunitypreventingexcessive immune cell activity that can lead to tissue destruction and autoimmunity

in poor immune responses against cancers expressing WT1resultingin poor immune responses against cancers expressing WT1

autoimmunity and controls T - cell reaction during infection to prevent excessive tissue damageto preventautoimmunity and controls T - cell reaction during infection to prevent excessive tissue damage

and cure the diseaseto preventand cure the disease

autoimmune disease and curtailing antitumour immune responsepreventingautoimmune disease and curtailing antitumour immune response

an overreaction with self and the development of autoimmune diseasepreventsan overreaction with self and the development of autoimmune disease

to tumoral immune resistance.1contributingto tumoral immune resistance.1

these autoreactive cells from causing disease [ 27preventsthese autoreactive cells from causing disease [ 27

in an ineffective adaptive immune responseresultingin an ineffective adaptive immune response

type 1 diabetes Todayto preventtype 1 diabetes Today

the immune system from clearing tumors ( 75preventthe immune system from clearing tumors ( 75

the immune system from attacking them.[38preventsthe immune system from attacking them.[38

the immune system from attacking them.[40preventsthe immune system from attacking them.[40

the immune system from attacking them.[47preventsthe immune system from attacking them.[47

Both autoimmune diseases and transplant complications(passive) are caused byBoth autoimmune diseases and transplant complications

the oval window membranepreventsthe oval window membrane

autoimmune disease or allergycausesautoimmune disease or allergy

in an adaptive immune response to a self - antigenresultingin an adaptive immune response to a self - antigen

to attack of self - antigens by the own immune systemleadingto attack of self - antigens by the own immune system

tumor growth and progressioncan causetumor growth and progression

to the immune system attacking normal tissuesleadingto the immune system attacking normal tissues

allograft rejection and regulating immune responses in both autoimmune disease and graft - versus - host diseasepreventingallograft rejection and regulating immune responses in both autoimmune disease and graft - versus - host disease

a disproportionate increase in the non - specific immune responsecausesa disproportionate increase in the non - specific immune response

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