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their inability to bind and present such peptides to T cells(passive) caused byimmune escape of cancer
research efforts ... the factorscontributetowards immune - escape
to believewill causeimmune collapse
immune reactionscausingimmune collapse
by legal and illegal drug(passive) caused byimmune collapse
Autoimmune cases ... the patient?s tissueprovokeimmune attack
intracellular contentscan provokeimmune attack
to have the look and feel of a commercial quality video game(passive) is designedImmune Attack
Mutations in the Pre - S genecan contributeto HBV immune escape
that AEP plays role in this critical moment(passive) been discoveredimmune systemhas
that line tumor blood vessels can limit the entry of immune effector cells into the tumor massthereby contributingto tumoral immune escape
down - regulation of NKG2D ligandscontributesto glioma immune escape
MicroRNA - mediated down - regulation of NKG2D ligandscontributesto glioma immune escape
Thisparticular activity by melanoma cells that results in immune escape ... Thisparticular activity by melanoma cellsresultsin immune escape
MicroRNA - mediated downregulation of NKG2D ligandscontributesto glioma immune escape
All these immune - inhibitory cellsmay contributeto immune escape
expression of surface moleculescontributeto immune escape
viral factorscontributingto immune escape
effector T cellsthus contributingto immune escape
the constant immune pressure ... the tumourleadsto immune escape
T - cell failureresultingfrom immune escape
virus - specific immune responsesleadingto immune escape
multiple mechanismscontributingto immune escape
r activity by melanoma cellsresultsin immune escape
the expression of PD - L1 on tumor cellscan leadto immune escape
antigenic variation arising from host immune pressurecan leadto immune escape
melanoma cellsresultsin immune escape
surface moleculescontributeto immune escape
The activation of alternative pathwaysleadsto immune escape
Thisparticular activity by melanoma cellsresultsin immune escape
causing T cell exhaustion and immune toleranceleadingto immune escape
Other mechanismsmay have contributedto immune escape
changes in the cancer cellsmay leadto immune escape
mutation or loss of a single classwill resultin immune escape
I antigen presentation ... cancermay contributeto immune escape
T cell exhaustionleadto immune escape
Loss of LILRB1 on malignant plasma cellscontributesto immune escape
Loss of LILRB1 on malignant plasma cellscontributesto immune escape
the cells and markerscan leadto immune escape
numerous mutationsleadto immune escape
in carcinogenesisresultingin carcinogenesis
to the development of checkpoint blockade antibody drugs that free T cells to attack and kill cancer cellsrapidly ledto the development of checkpoint blockade antibody drugs that free T cells to attack and kill cancer cells
the cellscausesthe cells
to the development of checkpointrapidly ledto the development of checkpoint
to tumor growthleadingto tumor growth
to the development of checkpoint blockade antibody drugsrapidly ledto the development of checkpoint blockade antibody drugs
vision losscausesvision loss
to the discovery of checkpoint moleculesledto the discovery of checkpoint molecules
to tumor relapseleadingto tumor relapse
bald patchescan causebald patches
to relapsescould leadto relapses
bald spotscausesbald spots
directlymay ... leaddirectly
of diseasescausedof diseases
to deathleadsto death
to the development of a clinically overt cancerleadingto the development of a clinically overt cancer
in the development of a clinically overt cancerresultingin the development of a clinically overt cancer
from tumor antigen lossresultsfrom tumor antigen loss
to future changes in growthmay contributeto future changes in growth
alsomay ... resultalso
to chronic inflammation which in turn leads to most of the diseases associated with agingleadto chronic inflammation which in turn leads to most of the diseases associated with aging
in severe outbreaksresultedin severe outbreaks
to a transmissionleadsto a transmission
usuallycauseusually
to the severity of the outbreakcontributingto the severity of the outbreak
to treatment failureleadingto treatment failure
to poor tumor clearance driving the development of therapies that promote anti - tumor immune responses ( 29 - 33contributesto poor tumor clearance driving the development of therapies that promote anti - tumor immune responses ( 29 - 33
to deathleadingto death
to the increased susceptibility to pathogens and cancercontributesto the increased susceptibility to pathogens and cancer
alsoresultsalso
alsocontributesalso
to an increased risk of infectionspotentially leadsto an increased risk of infections
to an increased risk of infectionspotentially leadsto an increased risk of infections
in the maintenance of relatively lower viral loads and clinical advantagemay ... resultin the maintenance of relatively lower viral loads and clinical advantage
to increased susceptibilityleadsto increased susceptibility
in increased incidence and severity of infectionresultsin increased incidence and severity of infection
vaginitis , oral candidiasis , cutaneous candidiasis , candidemia , and systemic infectionscausingvaginitis , oral candidiasis , cutaneous candidiasis , candidemia , and systemic infections
to higher septic riskleadingto higher septic risk
to a chronic infection with persistent inflammationleadingto a chronic infection with persistent inflammation
to autoimmune diseaseleadingto autoimmune disease