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Qaagi - Book of Why

Causes

Effects

arterial hypertension(passive) caused bycardiac hypertrophy

chronic pressure overload(passive) caused bycardiac hypertrophy

Hypertension alonecausedcardiac hypertrophy

Sustained hypertensioncausescardiac hypertrophy

prolonged hypertension(passive) caused bycardiac hypertrophy (

Li , Q. et al . Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1to provokecardiac hypertrophy

high blood pressure and a narrowing of the valves of the heart(passive) is ... caused byCardiac hypertrophy

Marano G. Pressure overloadcausescardiac hypertrophy

The greatest concerns regarding Clenbuterol side effects will revolve around the heart as usecan causecardiac methandienone hypertrophy

Select item 2057105318.Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1to provokecardiac hypertrophy

Long - term hypertensioncauseshypertrophy of the heart

hypertension 2.Restrictive(passive) caused byCardiac hypertrophy

Hypertension over a long periodscan causecardiac hypertrophy

| Hypertension Quinapril , an angiotensin converting enzyme inhibitorpreventscardiac hypertrophy

single - point mutations in genes encoding sarcomeric proteins including ventricular myosin regulatory light chain ( RLC(passive) caused bycardiac hypertrophy

congestive heart failure , hypertension , and pregnancy(passive) caused byCardiac hypertrophy

View Article Takeda Y , Yoneda T , Demura M , Miyamori I , Mabuchi H. Sodium - Induced Cardiac Aldosterone SynthesisCausesCardiac Hypertrophy

when the heart responds to increased stresses such as high blood pressure in the body or lungs(passive) is causedCardiac hypertrophy

excess GH.[1 ] Hypertension [ 1(passive) caused bybiventricular cardiac hypertrophy

excess GH as it is seen independent to hypertension(passive) caused byBiventricular cardiac hypertrophy

R.A. Transgenic overexpression of constitutively active protein kinase C epsiloncausesconcentric cardiac hypertrophy

aortic banding ( AB ) , phenylephrine ( PE ) or angiotensin II ( Ang II ) in vivo and in vitro(passive) caused bycardiac hypertrophy

PubMed - indexed for MEDLINE ] Related citations Select item 205710538.Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1to provokecardiac hypertrophy

Overexpression of Hopcausescardiac hypertrophy

Hdac2 overexpressionprovokessevere cardiac hypertrophy

Overexpression of SGLT1causespathologic cardiac hypertrophy

overexpression of CPβ2 andcausedcardiac hypertrophy

Overexpression of Hspb8causedcardiac hypertrophy

both pressure overload and G protein – coupled receptors , and knockout of p110γ(passive) triggered bymaladaptive cardiac hypertrophy

pressure overload in rats by successfully increasing endogenous NO levels(passive) caused bycardiac hypertrophy

An increase in mechanical load in the heart ... ( heart development , exercise and pregnancy ) or pathologically ( high blood pressure and heart - valve regurgitationcausescardiac hypertrophy

hemodynamic overload , which includes pressure overload ( PO ) caused by aortic stenosis and high blood pressure , and volume overload ( VO ) caused by valvular insufficiency , chronic myocardial infarction , arteriovenous shunt , and pregnancy(passive) is caused byCardiac hypertrophy

Breast Cancer Res Treat , 2013 Jan. PMID 23224145 , Free PMC Article Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1to provokecardiac hypertrophy

CL and D - CLcausedcardiac hypertrophy

pressure overload in vivo or by phenylephrine ( PE ) treatment of NRCMs in vitro(passive) caused bypathological cardiac hypertrophy

various reasons(passive) caused bythe cardiac hypertrophy

10.1111 / jcmm.13419 Hypertensioncausescardiac hypertrophy

authors Ernesto L. Schiffrin Peroxisome proliferator - activated receptor ( PPAR ) activationmay preventcardiac hypertrophy

Circulation 99 : 2694–2701 , 1999.OpenUrlAbstract / FREE Full Text ↵ Takeda Y , Yoneda T , Demura M , Miyamori I , and Mabuchi H. Sodium - induced cardiac aldosterone synthesiscausescardiac hypertrophy

smooth muscle cellsAbstractFulltextPDF{beta}-Adrenergic receptor stimulationcausescardiac hypertrophy

to heart failure ( HFcan leadto heart failure ( HF

to heart failure.[13can leadto heart failure.[13

231014 Heart failure(passive) caused by231014 Heart failure

to eventual heart failureleadingto eventual heart failure

towards heart failureleadingtowards heart failure

to dilatation and heart failureleadsto dilatation and heart failure

to heart failure in miceleadingto heart failure in mice

in heart failure and ventricular arrhythmiascan resultin heart failure and ventricular arrhythmias

to heart failure ( PubMed:20375365leadingto heart failure ( PubMed:20375365

to heart failure , which has been characterized extensivelyleadingto heart failure , which has been characterized extensively

heart failure ... and its mechanisms are largely unknowncausesheart failure ... and its mechanisms are largely unknown

to cardiac remodeling and even heart failurecan leadto cardiac remodeling and even heart failure

to heart failure without adequate therapycontributesto heart failure without adequate therapy

to the decreased contractility of the heart in heart failurecontributesto the decreased contractility of the heart in heart failure

to a premature death caused by heart failure [ 35leadingto a premature death caused by heart failure [ 35

to congestive heart failure , arrhythmia , and sudden deathleadsto congestive heart failure , arrhythmia , and sudden death

high blood pressure and congestive heart failurecan causehigh blood pressure and congestive heart failure

to heart failure , which is a leading cause of morbidity and mortalityeasily leadsto heart failure , which is a leading cause of morbidity and mortality

to heart failure between 6 – 9 months of ageleadsto heart failure between 6 – 9 months of age

to heart failure between 7–9 months of ageleadsto heart failure between 7–9 months of age

to heart failure , and is induced either by physiological stimulican leadto heart failure , and is induced either by physiological stimuli

to left ventricular systolic dysfunction and possibly heart failureleadingto left ventricular systolic dysfunction and possibly heart failure

dilated cardiomyopathy , heart failure , arrhythmias , and sudden death26 , 27causesdilated cardiomyopathy , heart failure , arrhythmias , and sudden death26 , 27

heart failure ... and its mechanisms are largely … ( More ) Yun - zeng Zou , Hiroshi Akazawa , +16 authors Issei Komurocausesheart failure ... and its mechanisms are largely … ( More ) Yun - zeng Zou , Hiroshi Akazawa , +16 authors Issei Komuro

in mitochondrial dysfunction , cardiomyocyte apoptosis , and heart failure ( Kang et al . , 2004 ; Bugger et al . , 2010can resultin mitochondrial dysfunction , cardiomyocyte apoptosis , and heart failure ( Kang et al . , 2004 ; Bugger et al . , 2010

to cardiomyopathy , heart failure , arrhythmia and even sudden cardiac death , which contribute to a major cause of morbidity and mortality [ 4,5may finally leadto cardiomyopathy , heart failure , arrhythmia and even sudden cardiac death , which contribute to a major cause of morbidity and mortality [ 4,5

to heart failure , in which the heart can no longer supply adequate amounts of blood to meet the body ’s hemodynamic demands , resulting in cardiac dilatation , thinning of the myocardial walls , decrease in contractile effectiveness , organ failure and deatheventually leadsto heart failure , in which the heart can no longer supply adequate amounts of blood to meet the body ’s hemodynamic demands , resulting in cardiac dilatation , thinning of the myocardial walls , decrease in contractile effectiveness , organ failure and death

an excessive increase in fibrosis , myocardial apoptosis , and heart failure ( 18).Nuclear factor ( NF)-κB proteins are a small family of related transcription factors that are known to play a key role in an immune responsecausesan excessive increase in fibrosis , myocardial apoptosis , and heart failure ( 18).Nuclear factor ( NF)-κB proteins are a small family of related transcription factors that are known to play a key role in an immune response

to heart disease and/or deathleadingto heart disease and/or death

to a heart attack and deathcan leadto a heart attack and death

heart diseases(passive) caused byheart diseases

in cardiac failure and sudden deathresultsin cardiac failure and sudden death

an enlarged heartcan causean enlarged heart

to compromised heart function and even deathleadingto compromised heart function and even death

to bradycardia / athlete ’s heartleadingto bradycardia / athlete ’s heart

to premature death in some casescan leadto premature death in some cases

the heart to thicken and weaken over timecausesthe heart to thicken and weaken over time

to an increase in the capillarisation of the heart muscle itselfalso leadsto an increase in the capillarisation of the heart muscle itself

to the vagal heart rate deficitmay contributeto the vagal heart rate deficit

in the decrease in the size of the heart chamberresultsin the decrease in the size of the heart chamber

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