by heterozygous inactivating germline mutations in the paternal allele of the GNAS gene(passive) caused byheterotopic ossification ( HO
by a gain of function mutation in the intracellular region of the BMP type I receptor kinase ALK2 , encoded by the gene ACVR1(passive) caused byheterotopic ossification
Activation of Hedgehog signaling by loss of GNAScausesheterotopic ossification
Activation of Hedgehog signaling by loss of GNAScausesheterotopic ossification
Hedgehog signaling by loss of GNAScausesheterotopic ossification
Reference Activation of Hedgehog signaling by loss of GNAScausesheterotopic ossification
by a gain of function mutation in the intracellular region of the BMP type I receptor kinase ALK2(passive) caused byheterotopic ossification
ACVR1 / ALK2can causeheterotopic ossification
by a gain of function mutation in the intracellular region of the BMP type I receptor kinase(passive) caused byheterotopic ossification
by a gain of function mutation in the intracellular region of the BMP type(passive) caused byheterotopic ossification
/ ALK2can causeheterotopic ossification
by the chronic tear of the ligament(passive) caused bythe sMCL ( heterotopic ossification
trauma ... in turnledto heterotopic ossification
even if the joint growth is due to endochondral ossificationcausesendochondral ossification
Another rare genetic disordercausingheterotopic ossification
any subperiosteal dissection becauseleaving the periosteum tendsto causeheterotopic ossification
subperiosteal dissection becauseleaving the periosteum tendsto causeheterotopic ossification
The genecausesossification
traumacan causeossification
by defects in Col II secretion(passive) caused byendochondral ossification
The proteincausesossification
by defects in Col II secretion and increased apoptosis(passive) caused byendochondral ossification
ankylosiscausingankylosis
the treatment of thoracic myelopathy(passive) caused bythe treatment of thoracic myelopathy
to bone deposition inleadsto bone deposition in
painmay causepain
compression of spinal cord(passive) caused bycompression of spinal cord
frequentlycausesfrequently
of collagencomposedof collagen
the cartilage to form bonewill promptthe cartilage to form bone
to the formation of the clavicles and cranial bonesleadsto the formation of the clavicles and cranial bones
the cartilagewill promptthe cartilage
in all bonesresultsin all bones
in elongation of the long bones and extension of the axial skeletonresultingin elongation of the long bones and extension of the axial skeleton
in increased heightresultsin increased height
in axial growthresultingin axial growth
alsocontributesalso
new bone to grow between vertebrae , eventually fusing them together and increasing the risk for fracturecausesnew bone to grow between vertebrae , eventually fusing them together and increasing the risk for fracture
this increase(passive) may have been caused bythis increase