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Qaagi - Book of Why

Causes

Effects

FactorsContributingto Herb - Drug Interactions UniqueTV

consumption of herbs and spices as part of a normal diet ... likelyto causeadverse herb - drug interactions

Wang BACKGROUND Phytochemical - mediated alterations in P - glycoprotein ( P - gp ) activitymay resultin herb - drug interactions

Hanxu Fu Background Phytochemical - mediated alterations in P - glycoprotein ( P - gp ) activitymay resultin herb - drug interactions

concomitant intake of anise oil preparations and drugs that act on CNSmay causeherb – drug interactions

not combined with drugsto preventdrug - herb interaction

prescription drugs ( 69 %could ... leadto herb - drug interactions

that concomitant intake of anise oil and medicinal products with action on the CNSmay causeherb – drug interactions

Savai J , Varghese A , Pandita N , Chintamaneni M. Several herbal drugs and allopathic medicines when co - administeredcan leadto severe herb - drug interactions

Chamomile is not recommended to be taken with aspirin or non - salicylate NSAIDs ( non - steroidal anti - inflammatory drugsmay causeherb - drug interaction

Jay Savai , Alice Varghese , Nancy S. Pandita , Meena Chintamaneni BACKGROUND Several herbal drugs and allopathic medicines when co - administeredcan leadto severe herb - drug interactions

Concomitant use of drugs and herbssometimes leadsto herb - drug interactions

Many herbal remediescreateherb / drug interactions

In order to avoid the medicine interactions as much as possible , it is urgentto discoverthe underlying herb - drug interactions

Yuan - Soon Ho Phytochemical - mediated alterations in P - glycoprotein ( P - gp ) activitymay resultin herb - drug interactions

Simultaneous taking of herbs and prescription medicationsmay causeherb - drug interactions

Concomitant use of herbs with conventional drugsmay leadto herb - drug interactions

should not be taken in conjunction with Clomid or other fertility drugscan causeherb - drug interaction

analyzing your medicationsto preventHerb - Drug Interaction

ClinicalTrials.gov ) BackgroundConcomitant use of herbs with drugsmay resultin herb - drug interactions

Patients who use herbal medication ... conventional drugscausesherb - drug interactions

DTS ... unlikelyto causeadverse herb - drug interactions

the co - administration of Fuzi with drugs that are substrates of DMEs and/or ETsmay causeherb - drug interactions ( HDIs

co - administration of P. amarus with drugs that are metabolized by CYP3A4may ... resultin herb - drug interactions

Graham ... to helppreventpotential herb - drug interactions

herbal medicines taken in conjunction with other medicationsmay causeunexpected herb - drug interactions

Like drugs , some herbal extracts and the constituents of their extracts alter cytochrome P450 ( CYP ) enzymescausingpotential herb - drug interactions

to complement your current prescription medicationsto preventherb - drug interactions

any uptake of products with high percentage of CXEE concurrently with therapeutic drugs primarily metabolized by UGT1A1 and UGT2B7may causeherb - drug interaction

that consumption of QR or TQ , in the form of food or dietary supplements , with drugs that are metabolized by CYP2C19 , CYP2D6 , or CYP3A4may causesignificant herb - drug interactions

Pregnane X receptor activation is knownto causeherb - drug interactions

the activation of the pregnane X receptor which is knownto causeherb - drug interactions

the relatively high K(i ) values in human CYP2C9 would suggest a low potentialto causeherb - drug interaction

St. Johns Wort ... reportedto causeherb - drug interactions

herbal medicines that are metabolized through sulfation , methylation and acetylation pathways(passive) caused bypotential herb - drug interactions

Herbal medicines can alter the activity of drug - metabolizing enzymes and transporterspotentially resultingin herb - drug interactions

The number of ADRs notified by pharmacovigilance systems in the world until 2012resultingfrom herb - drug interactions

contraindicated.7,8 Licorice root , known as gan cao in Chinese ... another commonly used examplecan causedrug - herb interactions

two different medicines working in the same or opposite directions and ultimately affecting the dose response and any mechanisms of therapeutic or toxic effects(passive) caused bythe pharmacodynamic herb - drug interactions

Several medicinal herbs , including St. John 's wort ( Henderson et al . , 2002 ; Mills et al . , 2004 ) , ginkgo biloba ( Yin et al . , 2004 ) , and kava ( Anke and Ramzan , 2004 ) , have been reportedto causeherb - drug interactions

from the concurrent use of herbal medicines and conventional prescription drugsmay resultfrom the concurrent use of herbal medicines and conventional prescription drugs

acute medical problems(passive) caused byacute medical problems

liver problems sulfasalazine mechanism of actioncan causeliver problems sulfasalazine mechanism of action

gastrointestinal problems , acne - like rashes and dizzinesscan ... however ... causegastrointestinal problems , acne - like rashes and dizziness

to adverse events including liver injurycan leadto adverse events including liver injury

in increased toxicity due to higher serum levels of cytostatics on the one hand or undertreatment due to decreased efficacy caused by lower serum levels on the other handresultingin increased toxicity due to higher serum levels of cytostatics on the one hand or undertreatment due to decreased efficacy caused by lower serum levels on the other hand

in loss of therapeutic effect or drug activity ( Antagonism ) , toxicity , unexpected increase in pharmacological activity(Additive effect ) , an increase or decrease in the side effect , and new side effect(s ) not previously knownoften resultin loss of therapeutic effect or drug activity ( Antagonism ) , toxicity , unexpected increase in pharmacological activity(Additive effect ) , an increase or decrease in the side effect , and new side effect(s ) not previously known

from concomitant use of herbal products with clinical drugsresultingfrom concomitant use of herbal products with clinical drugs

bioavailability leading to adverse eventsinfluencingbioavailability leading to adverse events

in serious adverse drug reactions | APhA DrugInfoLine Results of an extensive reviewcan resultin serious adverse drug reactions | APhA DrugInfoLine Results of an extensive review

unexpected adverse effects(passive) caused byunexpected adverse effects

serious adverse effectcan causeserious adverse effect

to Poisoning caused by atropine contamination of some commercial Rhodiola herbsresultsto Poisoning caused by atropine contamination of some commercial Rhodiola herbs

from taking turmeric with drugsmay resultfrom taking turmeric with drugs

contra - indications of medications with certain ingredients within supplementscausingcontra - indications of medications with certain ingredients within supplements

unexpected side effects of co - administered drugsmay causeunexpected side effects of co - administered drugs

potential side effects(passive) caused bypotential side effects

from the ... Pharmacokinetic Investigations | antihypertensive drugs | Caco-2 cells | Oleaceae | oleuropein | herb - drug interaction | Olea europaea subspeciesmay resultfrom the ... Pharmacokinetic Investigations | antihypertensive drugs | Caco-2 cells | Oleaceae | oleuropein | herb - drug interaction | Olea europaea subspecies

adverse reactionscan causeadverse reactions

troublecould causetrouble

qualitative activity and the synergistic or antagonizing properties of the medicinemay influencequalitative activity and the synergistic or antagonizing properties of the medicine

in whether elevating drug metabolism and lowering the bioavailability and efficacy of such drugs or reducing drug metabolism and enhancing adverse events antidiabetic agentscan resultin whether elevating drug metabolism and lowering the bioavailability and efficacy of such drugs or reducing drug metabolism and enhancing adverse events antidiabetic agents

in maniaresultingin mania

25 mg para que sirve amitriptyline logdcauses25 mg para que sirve amitriptyline logd

to serious adverse drug reactions ( ADRs ) or drug failurescan leadto serious adverse drug reactions ( ADRs ) or drug failures

HbA1C levels in patients used Insulin , OHG ( Figure 3 ) wherein patients used only PHPmight have influencedHbA1C levels in patients used Insulin , OHG ( Figure 3 ) wherein patients used only PHP

from the concomitant ingestion of goldenseal and CYP3A substratesmay resultfrom the concomitant ingestion of goldenseal and CYP3A substrates

between anesthesia and valerianmay resultbetween anesthesia and valerian

for use by practitioners , pharmacies , and insurance companiesdesignedfor use by practitioners , pharmacies , and insurance companies

potential safety concerns for patients taking GSE ( 129causingpotential safety concerns for patients taking GSE ( 129

in hepatotoxicity or significantly affect practicemay resultin hepatotoxicity or significantly affect practice

to increased side effects or reduced effectiveness of drug therapy ( see the section in this guide called Herb - Drug Interactionscan leadto increased side effects or reduced effectiveness of drug therapy ( see the section in this guide called Herb - Drug Interactions

the reported problem , looked at potential mechanisms through which it might have occurred , and evaluated how many case reports showed a “ very probable ” , “ probable ” , “ possible ” or “ doubtful ” drug interactioncausedthe reported problem , looked at potential mechanisms through which it might have occurred , and evaluated how many case reports showed a “ very probable ” , “ probable ” , “ possible ” or “ doubtful ” drug interaction

changes in metabolic routes , which could alter the functionality of drug metabolic enzymes and/or drug transporterscausechanges in metabolic routes , which could alter the functionality of drug metabolic enzymes and/or drug transporters

hypertensioncausehypertension

to morbidity or even mortalitycan leadto morbidity or even mortality

lamictaldoes ... causelamictal

harmful adverse effectscould causeharmful adverse effects

the risks(passive) caused bythe risks

from the modulation of the activities of cytochrome P450 ( P450can resultfrom the modulation of the activities of cytochrome P450 ( P450

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Smart Reasoning:

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