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Qaagi - Book of Why

Causes

Effects

blood flow entering the organ(passive) is influenced byHepatic clearance

mild hepatic injury from recurrent hepatitis - C virus(passive) caused byhepatic clearance of tacrolimus

i.e. , the metabolizing enzymatic activity(passive) is influencedhepatic clearance

Of other enzymes displaying activity ( UGT1A3 , UGT1A9 , UGT1A10-H , and UGT2B4 ) , UGT2B4 ( CLint , u 0.51 µl⋅min−1⋅mg−1 ) was estimatedto contribute significantlyto the hepatic clearance

two factors : the rate of hepatic blood flow ( which reflects the delivery of a drug to the liver ) and(passive) is influenced byHepatic clearance

the effective rate of desorption of a chemical from the plasma protein to which it is bound [ 52(passive) is influenced byHepatic clearance

dexamethasone(passive) caused byhepatic clearance

variably ... hepatic blood flow , intrinsic clearance , and plasma protein binding or predominantly by the hepatic blood flow at the highest hepatic clearance values(passive) is influenced ... byhepatic clearance

Unbound fraction and enzyme activitymay influencethe hepatic clearance

CYP factors ( Walle T. Assays of CYP2C8- and CYP3A4-mediated metabolism of taxol in vivo and in vitro(passive) is further influenced byHepatic clearance

correction : upsher - smith announces availability of Oxtriphylline products In most adaptive of these discussions patients reportcausesreduced hepatic clearance

in higher plasma levelsresultingin higher plasma levels

pulmonary inflammation Decamp , M. M. , Warner , A. E. , Molina , R. M. & Brain , J. D. , Jan 1 1992causingpulmonary inflammation Decamp , M. M. , Warner , A. E. , Molina , R. M. & Brain , J. D. , Jan 1 1992

to pyruvate accumulation resulting in increased lactate [ 24 ] orleadingto pyruvate accumulation resulting in increased lactate [ 24 ] or

from alterations in hepatic blood flow , Q a , and Q v , extrahepatic changesresultingfrom alterations in hepatic blood flow , Q a , and Q v , extrahepatic changes

at 99 % of QH , whereas setting the hepatic clearance at 90 % of the QH resulted in only 5-fold underpredictionwas setat 99 % of QH , whereas setting the hepatic clearance at 90 % of the QH resulted in only 5-fold underprediction

ication administration tion use in 2012 - 000194 pharmacies and sale for propecia tablets hospital , torquay , uk the healthcare professionals and emulsion for antigen - driven activation or other objectscausesication administration tion use in 2012 - 000194 pharmacies and sale for propecia tablets hospital , torquay , uk the healthcare professionals and emulsion for antigen - driven activation or other objects

from stimulation of cytochrome P450 activityresultingfrom stimulation of cytochrome P450 activity

to residual increase in bloodleadingto residual increase in blood

in NIR fluorescence signal throughout the GI tract that persists for hours , and/or 2resultsin NIR fluorescence signal throughout the GI tract that persists for hours , and/or 2

bupropion repaglinide(passive) caused bybupropion repaglinide

in significantly increased exposure to drugs ... particularly if they occur simultaneouslymay ... resultin significantly increased exposure to drugs ... particularly if they occur simultaneously

in decreased busulfan AUCresultingin decreased busulfan AUC

to a decrease in the plasma concentration of drugs that are substratesleadsto a decrease in the plasma concentration of drugs that are substrates

to band spreadingleadsto band spreading

to zerosetto zero

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