Loading ...

Blob

Smart Reasoning:

C&E

See more*

Qaagi - Book of Why

Causes

Effects

Deficiency of acid beta - glucocerebrosidasecauseswidespread accumulation of glucosylceramide - laden macrophages

The resulting cytotoxic oxidative stress induced on the cancer cellscausesmitochondrial apoptosis

capacityto causeapoptosis of alveolar macrophages

Lysis of tissue and phagocytosis of lipid material by histiocytesresultin sheets of lipid - laden macrophages ( xanthoma

This disruption of host cell protein kinase activitycausesapoptosis of macrophages

who showedcausedapoptosis in macrophages

adenosine alonecausesapoptosis in macrophages

YopP Cytotoxiccausesapoptosis of macrophages

Engulfmentcausesapoptosis in macrophages

clodronate liposomescauseapoptosis of macrophages

ERK - dependent formation of a phospho - c - Fos c - Jun activator protein-1 complexcausesapoptosis in macrophages

Lethal toxin of Bacillus anthraciscausesapoptosis of macrophages

order clodronate liposomescauseapoptosis of macrophages

How ... order clodronate liposomescauseapoptosis of macrophages

rare lesionscomposedof collections of lipid - laden macrophages

Encapsulated chlodronate works in an identical mannerto causeapoptosis in macrophages

that YC-1 inhibits oleate - induced lipid droplet formationleadingto lipolysis in lipid - laden macrophages

Subsequently , GlcCer and GlcSph accumulate ,leadingto the characteristic lipid laden macrophages

antibiotic usecausesintestinal macrophages

cholesterol levelsmay influenceclearance of hemosiderin - laden macrophages

by both host and parasite genetic factors(passive) is influenced bytrypanosome virulence

both host and parasite genetic factors(passive) is influenced bytrypanosome virulence

Both mechanismscauselysis of macrophages

The possible mechanisms by whichmay influencetrypanosome virulence

The drugcausesdegranulation of neutrophils

Ultrafine particlescausecytoskeletal dysfunctions in macrophages

ammonia and chloroquine(passive) caused bymacrophage antigen catabolism

by cigarette smoke in mice(passive) caused byalveolar macrophages

oxidised low density lipoprotein(passive) caused bymurine peritoneal macrophages

the leukocidincauseslysis of the neutrophils

release of cytokinesoriginatedfrom monocytes / macrophages

The granulomas are characteristicbeing composedof epithelioid macrophages

and/or chemokinesoriginatedfrom monocytes / macrophages

granulomascomposedof epithelioid macrophages

Multiple granulomascomposedof epithelioid macrophages

Endotoxin tendsto causesequestration of neutrophils

Respiratory burstleadspolymorphonuclear neutrophils ( PMN

from monocytes or from smooth muscle cellsoriginatingfrom monocytes or from smooth muscle cells

cytotoxicity(passive) caused bycytotoxicity

to extracellular deposition of tissue factor ( TF ) , some in particulate formcan leadto extracellular deposition of tissue factor ( TF ) , some in particulate form

in accumulation of lipids in the sub - endothelial spaceresultsin accumulation of lipids in the sub - endothelial space

in depletion of both pancreatic as well as intratumoral CD11b+ macrophages efficientlyresultedin depletion of both pancreatic as well as intratumoral CD11b+ macrophages efficiently

yellow nodulescausesyellow nodules

from monocytes or from smooth muscle cellsoriginatingfrom monocytes or from smooth muscle cells

local inflammatory responsescauseslocal inflammatory responses

tularemiacausestularemia

opportunistic infectionscauseopportunistic infections

acute and chronic pneumonia [ 1 , 2causingacute and chronic pneumonia [ 1 , 2

to a massive production of reactive oxygen species in inflamed tissue of inflammatory bowel disease patientsleadsto a massive production of reactive oxygen species in inflamed tissue of inflammatory bowel disease patients

colorectal cancer patient outcomecontributecolorectal cancer patient outcome

to metastatic angiogenesis and influence colorectal cancer patient outcomecontributeto metastatic angiogenesis and influence colorectal cancer patient outcome

further pro - inflammatory effectscausesfurther pro - inflammatory effects

Lymphogranuloma venereumcausingLymphogranuloma venereum

to the activation of inflammatory reactionsleadsto the activation of inflammatory reactions

to growth retardation and osteoporosisledto growth retardation and osteoporosis

to early skeletal growth retardation and progressive osteoporosisledto early skeletal growth retardation and progressive osteoporosis

from monocytes or from smooth muscle cellsoriginatingfrom monocytes or from smooth muscle cells

from monocytes or from smooth muscle cellsoriginatingfrom monocytes or from smooth muscle cells

symptoms(passive) caused bysymptoms

in the loss of protective functionwill resultin the loss of protective function

Insulin(passive) is caused byInsulin

allograft injury / rejection , tissue remodeling , or graft - site immunoregulationcan causeallograft injury / rejection , tissue remodeling , or graft - site immunoregulation

allograft injury / rejection , tissue remodeling , or graft - site immunoregulation via diverse mechanismscan causeallograft injury / rejection , tissue remodeling , or graft - site immunoregulation via diverse mechanisms

allograft injury / rejectioncan causeallograft injury / rejection

to a suggestion of umbilical endometriosisleadingto a suggestion of umbilical endometriosis

to resistance to chemotherapy in mouse modelsleadingto resistance to chemotherapy in mouse models

endothelial barrier function and impacts tumor cell migration dynamics ... among other modulation of the vessel barrierinfluencesendothelial barrier function and impacts tumor cell migration dynamics ... among other modulation of the vessel barrier

from monocytes or from smooth muscle cellsoriginatingfrom monocytes or from smooth muscle cells

injuryto causeinjury

significantly to the early stages of Wallerian degenerationcontributesignificantly to the early stages of Wallerian degeneration

to lymphangiogenesis as the major producer of vascular endothelial growth factor C ( VEGF - C ) in cutaneous wound healingcontributeto lymphangiogenesis as the major producer of vascular endothelial growth factor C ( VEGF - C ) in cutaneous wound healing

to hepatosplenomegalyleadingto hepatosplenomegaly

Blob

Smart Reasoning:

C&E

See more*