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0054]This result ... the intron-8 encoded domaincould leadto altered biochemical and biological properties among ECDIIIa - containing protein variants
0111]This result ... the intron-8 encoded domaincould leadto altered biochemical and biological properties among ECDIIIa - containing protein variants
Clinical and Hematologic Features and Molecular Basis | University of Utah Hemoglobinopathies : Clinical and Hematologic Features and Molecular Basis Mutations in the globin genescan resultin hemoglobin variants or thalassemias
sequence variantsleadingto haemoglobin variants , thalassaemias , and haemoglobinopathies ' Human Hemoglobin Variants and Thalassemias
This result ... several variations in the intron-8 encoded domaincould leadto altered biochemical and biological properties among ECDIIIa - containing protein variants
Experimentsdesignedto study splice variants , epigenetic modifications ( methylation ) and
thalassemias , which are caused by mutations that severely reduce or completely abolish globin gene expression , and diseases caused by mutationsresultin pathologic structural variants of hemoglobin
luspaterceptcan preventanemia in a different way than erythropoietin derivatives , which include Epogen and Aranesp
one scoresetfor nucleotide variants and another for amino acid variants
Ureacauseshemoglobin S ( and structural variants of hemoglobin S ) to dissolve
profoundlyinfluenceprofoundly
to improve the therapeutic properties of the natural molecules by addressing multiple biological targets and physiologic pathways that have been validated as key targets in central nervous system , auto - immune , inflammatory , metabolic , and fibrotic diseasesspecifically designedto improve the therapeutic properties of the natural molecules by addressing multiple biological targets and physiologic pathways that have been validated as key targets in central nervous system , auto - immune , inflammatory , metabolic , and fibrotic diseases
in a single amino acid substitution , such as hemoglobin S. Two classic techniques used in the clinical laboratory , cation exchange ( CE)-HPLC and capillary zone electrophoresis ( CZEresultin a single amino acid substitution , such as hemoglobin S. Two classic techniques used in the clinical laboratory , cation exchange ( CE)-HPLC and capillary zone electrophoresis ( CZE
the transcription and/or translation of target proteinsmay influencethe transcription and/or translation of target proteins
thalassemiacausethalassemia
the distribution of msp1 and(passive) could be influenced bythe distribution of msp1 and
The column(passive) is designedThe column
to improve the therapeutic properties of these natural compounds by addressing multiple biological targets and physiologic pathways that have been demonstrated to play key roles in specific central nervous system ( CNSspecifically designedto improve the therapeutic properties of these natural compounds by addressing multiple biological targets and physiologic pathways that have been demonstrated to play key roles in specific central nervous system ( CNS