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first(passive) was ... discoveredHedgehog signaling pathway
The fruit is knownto preventhedgehog signaling
binding of ligands with transmembrane receptor Ptch(passive) is triggered byHedgehog signaling
new mutationsinfluenceHedgehog signaling
four mutationsinfluenceHedgehog signaling
new gene fusions and mutations linked to subset of GIST patientsdiscoverHedgehog signaling pathway
of different signalling proteins belonging to the “ Hedgehog ” family , one of the most common ones being Sonic Hedgehog ( Shh(passive) is composedThe hedgehog signalling pathway
new information about the distinct functions TSC1 and TSC2 ... the various signaling pathwaysinfluenceHedgehog signaling
the secreted Hedgehog ligand , which binds and inhibits Patched(passive) is triggered byHedgehog signaling
new mutantsinfluencehedgehog signaling
of the PTCH - SMO - GLI axis(passive) is composedThe hedgehog signaling pathway
the microenvironment of a tumorcan influenceHedgehog Signaling
Benazepril , the active substance anywhere in Lotensin 10 mg ... tightly controlscausesthe hedgehog signalling pathway
in the 1980s(passive) was first discoveredThe hedgehog signaling pathway
lipid - related genesinfluencehedgehog signaling
a German research teamdiscoveredanother hedgehog signaling pathway
Success Kinome little interfering RNA screeningto discoverHedgehog pathway
of three parts(passive) is mainly composedThe Hedgehog signaling pathway
complex and diverse mechanisms , including ligand gradients , noncanonical signaling mechanisms , and combinatorial activities of repressor and activator forms of the Gli transcription factors(passive) is influenced byHedgehog signaling
cyclopaminepreventHedgehog signaling
genetic alterationscauseHedgehog pathway upregulation
basal cell proliferation and tumor growth.12can causebasal cell proliferation and tumor growth.12
through genetic analysis during Drosophila developmentdiscoveredthrough genetic analysis during Drosophila development
to the carcinogenesis of the skin mainly BCC ( Basal Cell Carcinomamight leadto the carcinogenesis of the skin mainly BCC ( Basal Cell Carcinoma
to excessive NPC proliferationleadingto excessive NPC proliferation
in 1980 by Christiane Nüsslein - Volhard and Eric Wieschaus in their studies of the molecular events that control segment polarity in developing Drosophila larvaewas discoveredin 1980 by Christiane Nüsslein - Volhard and Eric Wieschaus in their studies of the molecular events that control segment polarity in developing Drosophila larvae
to breast cancer development by stimulating proliferationmay contributeto breast cancer development by stimulating proliferation
to taste bud loss , papilla disruption , and decreased proliferation in domains of papilla epithelium that contribute to taste cellsrapidly ledto taste bud loss , papilla disruption , and decreased proliferation in domains of papilla epithelium that contribute to taste cells
an immune suppressive environment through regulation of MDSC population , which is in parallel with hedgehog signaling - mediated cell proliferation that promotes carcinogenesiscreatesan immune suppressive environment through regulation of MDSC population , which is in parallel with hedgehog signaling - mediated cell proliferation that promotes carcinogenesis
to activation of the Gli proteins which in turn contribute to the signalling cascade that promotes tumour growth and developmentleadsto activation of the Gli proteins which in turn contribute to the signalling cascade that promotes tumour growth and development
alsooriginatedalso
to tumorigenesisleadingto tumorigenesis
heterotopic bone formation in POHto causeheterotopic bone formation in POH
the migration of glia and neurons in the developing fruit fly ( Rangarajan et al .can influencethe migration of glia and neurons in the developing fruit fly ( Rangarajan et al .
Novel GIST animal model(passive) caused byNovel GIST animal model
weight gain in mice fed a high - fat dietcan preventweight gain in mice fed a high - fat diet
the induction of genes encoding Wnt2 , Wnt4 , and Fgf16 ( fibroblast growth factor 16 ) in the stromatriggeredthe induction of genes encoding Wnt2 , Wnt4 , and Fgf16 ( fibroblast growth factor 16 ) in the stroma
in molecular chatter that overall promotes tumor progressionresultingin molecular chatter that overall promotes tumor progression
to their overall ... et alleadto their overall ... et al
that process 's timing(passive) influenced bythat process 's timing
a breakdown of the normal regenerative properties of the lung airways , leading to degenerative disease statescausesa breakdown of the normal regenerative properties of the lung airways , leading to degenerative disease states
other ciliary GPCRsto influenceother ciliary GPCRs
to development of desmoplastic stroma that characterizes pancreatic canceralso contributesto development of desmoplastic stroma that characterizes pancreatic cancer
to the development of bladder cancers ( 38 , 39may contributeto the development of bladder cancers ( 38 , 39
to generalized , non - photoreceptor - specific delay of retinal neurogenesisleadsto generalized , non - photoreceptor - specific delay of retinal neurogenesis
rapidlyledrapidly
basal cell carcinoma , the most common skin cancer and one of the most common cancerscausesbasal cell carcinoma , the most common skin cancer and one of the most common cancers
to cancer in patients deficient for the nutrient zinccan contributeto cancer in patients deficient for the nutrient zinc
to Front Door | Photo ‹› Hedgehog Crossing Pathway that Leads to FrontLeadsto Front Door | Photo ‹› Hedgehog Crossing Pathway that Leads to Front
to Wnt activationpotentially contributingto Wnt activation
to the anti - CSC effect of genistein in PCa TCsmay contributeto the anti - CSC effect of genistein in PCa TCs
in severe acrania‐holoprosencephaly‐agnathia craniofacial defectsresultingin severe acrania‐holoprosencephaly‐agnathia craniofacial defects
the ciliary accumulation of SMO(passive) normally caused bythe ciliary accumulation of SMO
in severe acraniaholoprosencephaly - agnathia craniofacial defectsresultingin severe acraniaholoprosencephaly - agnathia craniofacial defects
hair follicle morphogenesis defectscauseshair follicle morphogenesis defects
to multifactorial drug resistance in cancercan contributeto multifactorial drug resistance in cancer