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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

the gut wallcausinggut permeability ( leaky gut

The integrity of the gut lining may be compromisedcontributingto gut permeability ( leaky gut

by irritation of the gut lining by increased acidity(passive) caused byincreased gut permeability

irritation of the gut lining by increased acidity(passive) caused byincreased gut permeability

irritation of the gut lining by the increased acidity(passive) caused byincreased gut permeability

the concern ... gut dysbiosis ( imbalance of gut microbes / bacteriacan leadto increased gut permeability

Low feed intake associated with heat stress has been shownto contributeto increased gut permeability

in our gut liningleadingto increased gut permeability

intestinal bacteria imbalancescauseincreased gut permeability

junctions in our gut liningleadingto increased gut permeability

increase the zonulin levelsleadingto increased gut permeability

by irritation of the gut lining(passive) caused byincreased gut permeability

Factorscan leadto increased gut permeability

These factorscontributeto increased gut permeability

inflammation(passive) is ... caused byan increased gut permeability

a diet high in added sugars and artificial ingredients ... inflammationcan leadto increased gut permeability

by a lack of fermentable fiber and polyphenols in the diet that allows microbial fragments to enter the blood and initiate increase inflammation that can spread to the brain(passive) caused byincreased gut permeability

the intestinal mucosamight contributeto increased gut permeability

Alcoholcan leadto increased gut permeability

the mechanisms by whichcontributesto increased gut permeability

intestinal healingcould leadto increased gut permeability

the adherence of harmful microbes to the gut wallcan leadto increased gut permeability

these added sugarsleadincreased gut permeability

these added sugarsleadto increased gut permeability

IBD conditionsleadingto increased gut permeability

intestinal TJ integrityleadingto increased gut permeability

impaired mucosal barrier functionleadingto increased gut permeability

Medications and environmental toxinscan also contributeto increased gut permeability

by expression of a protein called Zonulin(passive) caused byincreased gut permeability

The damaged cell surfacecausesincreased gut permeability

the culpritpotentially causingincreased gut permeability

Excessive alcohol intakeleadsto increased gut permeability

which induced excess IL-17A production in a TLR2-dependent mannerresultingin increased gut permeability

In atherosclerosis - associated ailments like obesity , hypertension and type II diabetes , intercellular tight junctions are impairedleadingto increased gut permeability

by means of high levels of circulating oestrogen(passive) caused bygut wall permeability

by high levels of circulating oestrogen(passive) caused bygut obstruction permeability

that sand is not a good substratecan causegut blockages

the role played by microbiota modifications in the processescauseenhanced gut permeability

by decreased bile acids(passive) may be caused byGut microbial dysbiosis

food sensitivitiescauseintestinal gut permeability

to food allergiesleadingto food allergies

to increased bacterial translocationleadingto increased bacterial translocation

more inflammationcausesmore inflammation

to the translocation of inflammatory bacterial components to the liver through the portal systemleadingto the translocation of inflammatory bacterial components to the liver through the portal system

High endotoxin levels(passive) might be caused byHigh endotoxin levels

absorption of macromolecules from the intestinal contentcausingabsorption of macromolecules from the intestinal content

to the translocation of inflammatory bacterial componentsleadingto the translocation of inflammatory bacterial components

in even more potentially toxic substances from the gut being absorbed to put further stress on the liver 's detoxification pathwaysresultsin even more potentially toxic substances from the gut being absorbed to put further stress on the liver 's detoxification pathways

from SmallResultingfrom Small

to more serious health issues down the trackcould leadto more serious health issues down the track

to translocation of the commensal bacteria across the epithelial barrier resulting in significant damage to local tissues , which can result in chronic gut abnormalities in sensitive individualsleadingto translocation of the commensal bacteria across the epithelial barrier resulting in significant damage to local tissues , which can result in chronic gut abnormalities in sensitive individuals

to increase trafficking of macromoleculesleadingto increase trafficking of macromolecules

to Leaky Gut Syndromeleadsto Leaky Gut Syndrome

to absorption of undigested proteins which our immune system then tags as foreignleadsto absorption of undigested proteins which our immune system then tags as foreign

to metabolic endotoxemialeadingto metabolic endotoxemia

to translocation of the commensal bacteria across the epithelial barrierleadingto translocation of the commensal bacteria across the epithelial barrier

in a condition known as leaky gutcan resultin a condition known as leaky gut

to autoimmunityleadsto autoimmunity

in elevated levels of the food antibodiescould potentially resultin elevated levels of the food antibodies

by glutencausedby gluten

in induction ofresultsin induction of

The very first stimulation of this bone - destroying process(passive) was caused byThe very first stimulation of this bone - destroying process

to a relevant influx of toxins and undigested proteins into the blood streamleadingto a relevant influx of toxins and undigested proteins into the blood stream

to liver injurycontributesto liver injury

in elevated lipopolysaccharide ( LPS ) absorption into blood from the lumen of the intestineresultsin elevated lipopolysaccharide ( LPS ) absorption into blood from the lumen of the intestine

to translocation of the commensal bacteria across the epithelial barrier resulting in significant damage to local tissues which is likely to result in chronic gut abnormalities in sensitive individualsleadingto translocation of the commensal bacteria across the epithelial barrier resulting in significant damage to local tissues which is likely to result in chronic gut abnormalities in sensitive individuals

to translocation of your commensal microorganisms across the epithelial barrierleadingto translocation of your commensal microorganisms across the epithelial barrier

to the leakage of LPS and possibly other microbiota derived factorsleadingto the leakage of LPS and possibly other microbiota derived factors

from exertion and hypoxiaresultingfrom exertion and hypoxia

in ALS like symptoms ... without ALScan resultin ALS like symptoms ... without ALS

inflammationcausinginflammation

absorption of potentially toxic dietary substances and products of incomplete digestion , which are regarded by the body as foreign substances requiring ' attack ' when in fact with adequate digestion and normal permeability they would not compromise optimum functioncan causeabsorption of potentially toxic dietary substances and products of incomplete digestion , which are regarded by the body as foreign substances requiring ' attack ' when in fact with adequate digestion and normal permeability they would not compromise optimum function

to the translocation of prolamins and glutelins to organ tissuesleadsto the translocation of prolamins and glutelins to organ tissues

from reduced gut blood flowresultfrom reduced gut blood flow

from ethanol- or acetaldehyde - induced impairment of tight junctionsresultingfrom ethanol- or acetaldehyde - induced impairment of tight junctions

leaky gut syndromecausingleaky gut syndrome

to leaky gut syndromeleadingto leaky gut syndrome

the body to develop auto immune diseasesmay causethe body to develop auto immune diseases

in leakage of fluid , protein and blood into the gut lumencan resultin leakage of fluid , protein and blood into the gut lumen

gut stasiscausinggut stasis

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Smart Reasoning:

C&E

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