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Qaagi - Book of Why

Causes

Effects

TLR2 ) stimulationresultingin the release of cytokines including granulocyte colony - stimulating factor , with interesting biological impact

cellsledto the discovery of colony - stimulating factors ( CSFs ) , including macrophage colony - stimulating factor , granulocyte colony - stimulating factor and granulocyte

the colonies of white stem cells within the bone marrowcausingthe level of neutrophils in the blood to rise ( Granulocyte Colony Stimulating Factor - GCSF

Interleukin-10contributesdevelopment of macrophage suppressor activities by macrophage colony - stimulating factor

A studywas designedto assess the effect of subcutaneous molgramostin ( granulocyte - macrophage colony stimulating factor

by inhibition of programmed cell death Blood(passive) is caused byProlongation of survival of human polymorphonuclear neutrophils by granulocyte - macrophage colony - stimulating factor

inhibition of programmed cell death(passive) is caused byProlongation of survival of human polymorphonuclear neutrophils by granulocyte - macrophage colony - stimulating factor

the latterleadingto increased generation of macrophage - colony stimulating factor

T cellsleadingto less granulocyte colony - stimulating factor ( G - CSF

a chromosomal translocationleadingto overexpression of colony - stimulating factor ( CSF)1

Factorsinfluencingvitro production of colony - stimulating factors

techniques to culture blood cellsledto the discovery of colony - stimulating factors ( CSFs

specialized culture techniques for growing blood cellsledto the discovery of colony - stimulating factors ( CSFs

These culturesledto the discovery of the colony - stimulating factors ( CSF

growing blood cellsledto the discovery of colony - stimulating factors ( CSFs

blood cellsledto the discovery of colony - stimulating factors ( CSFs

a vaccinecomposedof whole tumor cells expressing granulocyte macrophage colony - stimulating factor

first(passive) was ... discoveredGranulocyte - macrophage colony - stimulating factor ( GM - CSF

Dr. Moorediscoveredgranulocyte colony stimulating factor ( G - CSF

Conditionsinfluencinginhibitors of the colony - stimulating factor ( CSF

also(passive) have been ... discoveredGranulocyte colony stimulating factor receptor ) [ 49

The risk factorscan causethis setting , macrophage colony - stimulating factor

Professor Nicola ... the teamdiscoveredcolony stimulating factors ( CSFs

Professor Don Metcalf ( 1929 - 2014discoveredColony Stimulating Factors at the WEHI in the mid-1960s

a patient with neutrophiliaresultingfrom endogenous granulocyte - colony stimulating factor overproduction

Recently , Fontana et al ( 7 ) have shown the inhibitory role of miRNA 17 - 5P-20a-106a in monocytopoiesis through targeting AML1 ( Figure 3 ) , a subunit of core binding factorleadingto downregulation of macrophage colony - stimulating factor receptor

Professor Don Metcalf at the Walter & Eliza Hall Institute of Medical Research(passive) discovered bygranulocyte colony stimulating factor

Platzer v. Sloan - Kettering ( MSKCC)(1992 ) - Dr. Platzer and four othersinventedColony Stimulating Factor

DrugscausedColony - stimulating

in an enhanced respiratory burst , prolonged survival , and increased tumor cell killingresultsin an enhanced respiratory burst , prolonged survival , and increased tumor cell killing

to the host response in severe sepsismight contributeto the host response in severe sepsis

pulmonary alveolar proteinosis(passive) caused bypulmonary alveolar proteinosis

selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cyclecausesselective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle

in accelerated engraftment in this group of patientsresultsin accelerated engraftment in this group of patients

hematopoietic stem cellsinfluenceshematopoietic stem cells

selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cyclecausesselective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle

selective mobilization of bone marrow hematopoietic stem cells into the bloodcausesselective mobilization of bone marrow hematopoietic stem cells into the blood

to an increment of neutophils via stimulation of bone marrow granulocytic cellsleadsto an increment of neutophils via stimulation of bone marrow granulocytic cells

selective mobilization of bone marrow hematopoietic stem cellscausesselective mobilization of bone marrow hematopoietic stem cells

The side effects listed below(passive) might be caused byThe side effects listed below

from inflammation caused by the stoneresultingfrom inflammation caused by the stone

to decrease incidence of infection from febrile neutropenia associated with patients who have nonmyeloid malignancies receiving anti - cancer myelosuppressive therapydesignedto decrease incidence of infection from febrile neutropenia associated with patients who have nonmyeloid malignancies receiving anti - cancer myelosuppressive therapy

to enhanced monocyte survival in chronic atopic dermatitiscontributesto enhanced monocyte survival in chronic atopic dermatitis

in a persistent idiopathic neutropenia ( Lanevschi et al . , 1999can also resultin a persistent idiopathic neutropenia ( Lanevschi et al . , 1999

to increased recruitment of neutrophils andleadto increased recruitment of neutrophils and

to the increase in the neutrophil countcontributedto the increase in the neutrophil count

shortness of breath Side Effectsmay causeshortness of breath Side Effects

marrow hypercellularity which is evident on diffusioncan causemarrow hypercellularity which is evident on diffusion

marrow hypercellularity which is evident on diffusion weighted MRI ( 3can causemarrow hypercellularity which is evident on diffusion weighted MRI ( 3

macrophage homeostasisinfluencesmacrophage homeostasis

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