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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

Unfortunately , alloreactive T cells also attack nonmalignant host tissuescausinggraft - versus - host disease ( GVHD

After the allogeneic transplant , the transplanted stem cells or the cells developed from it can react against the hostcausinggraft - versus - host disease ( GVHD

donor attack recipient normal tissuescausinggraft versus host disease GvHD

Host alloreactive T - cellscan causegraft - versus - host disease ( GVHD

However , alloreactive T cells also attack recipient nonmalignant cellscausinggraft - versus - host disease ( GVHD

Those T - cells in a haploidentical donor graftwould causeGraft - versus - Host - Disease ( GvHD

by allogeneic T cells recognizing molecules of the recipient as foreign(passive) is caused byGraft - versus - host disease ( GvHD

Mature donor T cellscausegraft - versus - host disease ( GVHD

T lymphocytes ... the same cellscausegraft versus host disease ( GVHD

the new , donor immune system ... the patientcausesgraft versus host disease ( GvHD

alloreactive T cellscausegraft - versus - host disease ( GVHD

the alloreactive T cellscausinggraft - versus - host disease ( GVHD

host tissue and organscausinggraft versus host disease ( GVHD

T - cellscausingGraft - versus - Host - Disease ( GVHD

T - cellscauseGraft - versus - Host - Disease ( GVHD

The T cells ... the cellscauseGraft Versus Host Disease ( " GVHD

cellswill causegraft - versus - host disease " ( GVHD

the cellscausegraft - versus - host disease [ GVHD

T cellscan causegraft - versus - host disease ( GVHD

Those T - cells in a haploidentical graftwould causeGraft - versus - Host - Disease ( GvHD

healthy host tissuescausinggraft - versus - host disease ( GVHD

the activation of donor lymphocytes leading to immune damage to the skin , gut , and liver in the recipient(passive) is caused byGraft - versus - host disease ( GVHD

the direct pathway of allorecognition ... donor T cellsprovokegraft - versus - host - disease ( GVHD

Allografts that contain T cells of the donorcan causegraft - versus - host disease ( GVHD

NK - cells , but not T - cellsdo ... causegraft - versus - host disease ( GVHD

a haploidentical donor graftwould causeGraft - versus - Host - Disease ( GvHD

normal tissuesleadingto graft - versus - host disease ( GVHD

the recipientcausinggraft - versus - host - disease " ( GVHD

TCR deficient T cellswould ... causegraft versus host disease ( GVHD

by the transplanted lymphocytes(passive) caused byGraft - versus - Host Disease ; GvHD

the transplanted immune system recognizing(passive) is caused byGraft - versus - host disease ( GVHD

immune cellscausegraft - versus - host disease ( GVHD

less likelyto causegraft - versus - host disease ( GVHD

the transplanted immune cells may also harm normal tissuescausinggraft - versus - host disease ( GVHD

tissue rejectioncausingGraft - Versus - Host - Disease ( GVHD

a haploidentical graftwould causeGraft - versus - Host - Disease ( GvHD

the transplanted immune system recognizing and attacking the recipient 's body(passive) is caused byGraft - versus - host disease ( GVHD

allogeneic NK cellsdo ... causegraft versus host disease ( GVHD

the immunobiology mechanismsinfluencegraft - versus - host disease ( GVHD

some light ... the immune cellscausegraft - versus - host disease ( GVHD

to significant treatment related mortalityleadingto significant treatment related mortality

your ability to eat to be decreasedcausesyour ability to eat to be decreased

to chronic GvHDcan leadto chronic GvHD

transplant related mortality(passive) caused bytransplant related mortality

severe intestinal inflammationcan causesevere intestinal inflammation

significant mortality in patients undergoing allogeneic hematopoietic cell transplantationcausessignificant mortality in patients undergoing allogeneic hematopoietic cell transplantation

treatment complicationscausingtreatment complications

significant morbidity and mortality in patientscausessignificant morbidity and mortality in patients

mortality(passive) caused bymortality

to profound T - cell deficiencycan contributeto profound T - cell deficiency

diarrhea(passive) caused bydiarrhea

from recognition of host antigensresultsfrom recognition of host antigens

morbidity and mortality after HSCTcausesmorbidity and mortality after HSCT

serious mortality and morbiditycausingserious mortality and morbidity

an attack on the tear glands of the eyecausesan attack on the tear glands of the eye

to problems with organ functioncan leadto problems with organ function

significant morbiditycan causesignificant morbidity

lung disease after bone marrow transplantscan causelung disease after bone marrow transplants

to the failure of the transplanted organ and other chronic and acute problemscan ... leadto the failure of the transplanted organ and other chronic and acute problems

when the T cells attack the recipient 's tissuescausedwhen the T cells attack the recipient 's tissues

without infectiondid ... resultwithout infection

deathcan causedeath

new transplanted bone marrow to attack patients tissues and bonescausesnew transplanted bone marrow to attack patients tissues and bones

damagecausesdamage

alsoleadsalso

alsoleadsalso

secondary complications(passive) caused bysecondary complications

to chronic disabilitycan leadto chronic disability

mainly the reduction of mortality(passive) caused bymainly the reduction of mortality

mortality(passive) caused bymortality

fatal liver failure(passive) caused byfatal liver failure

from a donor recognize and mount a deleterious immune response against antigens found in the immunocompromised recipientoriginatingfrom a donor recognize and mount a deleterious immune response against antigens found in the immunocompromised recipient

from donor lymphocytes attacking normal host cellsresultsfrom donor lymphocytes attacking normal host cells

to fewer infectionshas ledto fewer infections

to new mechanism - based therapiescan leadto new mechanism - based therapies

all sort of problemsis causingall sort of problems

serious complicationscould causeserious complications

donor rejection(passive) caused bydonor rejection

this rash(passive) is caused bythis rash

tissue damage(passive) caused bytissue damage

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Smart Reasoning:

C&E

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