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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

Virusesmay causeincompatibility and graft failure

vein graft disease ... more likelyto causegraft failure

Abnormal pressure placed on a graftcan causegraft failure

the factorscausinggraft failure

Factorsinfluencinggraft failure

CMV can also lower the immune system and the virus and/or treatmentcan causegraft failure

the most common event ... , andcausinggraft failure

the most common technical complicationcausesgraft failure

the outcomes and factorsinfluencinggraft failure

rejection and degrade over timeto causegraft failure

the existing infectionmay causegraft failure

infectioncausinggraft failure

treatmentcan causegraft failure

Acute rejectioncausedgraft failure

chronic rejectioncausinggraft failure

eventswill causegraft failure

any other disease recurrent diseasecausinggraft failure

areacausedgraft failure

You do not want this pressure on the grafted areawill causegraft failure

kidney transplantationcausesgraft failure

by the patient(passive) caused byGraft failure

3]Excessive portal flowcausesgraft failure

the same elementscausegraft failure

An inadequate volume of grafted bonecan causegraft failure

The most common pathogencausinggraft failure

two significant areas of remodeling : a stenosis with over 85 % reduction in area ,causedgraft failure

available evidencecausesgraft failure

pulmonary venous thrombosiscausinggraft failure

The non - anatomic positioning of the graftmay causegraft failure

The most common pathogenscausinggraft failure

the potential for competitive flow from native vesselsto causegraft failure

fewer KIDNEY TRANSPLANTATIONcausegraft failure

by radiation(passive) caused bygraft failure

Cardiovascularcausesgraft failure

Infection causing ulceration leading to scarringmay occasionally causegraft failure

Chronic Allograft Nephropathy ( CANcausesgraft failure

the major problemcausinggraft failure

Excessive tension in the graft ... tenting or non - conformancecan causegraft failure

the thickening of blood vesselscan causegraft failure

Development of de novo donor - specific antibodies ( dnDSA ) is knownto causegraft failure

the tree to break apartcausethe tree to break apart

to an adverse clinical event ... and not all clinical events following CABG are caused by graft failureleadsto an adverse clinical event ... and not all clinical events following CABG are caused by graft failure

due to causes other than acute rejectionmainly resultsdue to causes other than acute rejection

in major bleeding and/or an infectioncan resultin major bleeding and/or an infection

to serious bleeding and/or infectioncan leadto serious bleeding and/or infection

in death orresultingin death or

to deathledto death

problems(passive) are caused byproblems

to revision surgeryleadingto revision surgery

in retransplantation or patient deathmay resultin retransplantation or patient death

from long ischemic timecan resultfrom long ischemic time

to bleeding and infectionscan leadto bleeding and infections

to second transplantationleadingto second transplantation

major amputationcausedmajor amputation

to an adverse clinical eventleadsto an adverse clinical event

from insufficient flowresultingfrom insufficient flow

in considerable mortality ( 20resultedin considerable mortality ( 20

usuallyleadsusually

from ischemia - reperfusion injuryresultingfrom ischemia - reperfusion injury

from diverse processescan resultfrom diverse processes

to a requirement for urgent retransplantationledto a requirement for urgent retransplantation

in 63.6 % of cases and a three - fold increase in BCVA < 6/60resultedin 63.6 % of cases and a three - fold increase in BCVA < 6/60

in relapse of paroxysmal nocturnal haemoglobinuria 3 weeks prior to presentationresultingin relapse of paroxysmal nocturnal haemoglobinuria 3 weeks prior to presentation

to graft lossleadingto graft loss

from acute rejectionresultingfrom acute rejection

in ischemic graft lossoften resultingin ischemic graft loss

in 10 major amputationsresultedin 10 major amputations

in slow boot and other problemswill resultin slow boot and other problems

to allograft failuremay leadto allograft failure

to graft rejection or graft - versus - host diseaseleadingto graft rejection or graft - versus - host disease

alsomay ... contributealso

from graft thrombosis.[22],[37resultingfrom graft thrombosis.[22],[37

from alcohol relapsesresultingfrom alcohol relapses

in early postoperative graft stenosis and occlusioncan resultin early postoperative graft stenosis and occlusion

to one mortalityledto one mortality

to only partial augmentation or complete failure of the graftleadingto only partial augmentation or complete failure of the graft

tissue graft rejection(passive) caused bytissue graft rejection

Acute hemolytic transfusion reactions(passive) are usually caused byAcute hemolytic transfusion reactions

in hemolytic disease of the newborncan also resultin hemolytic disease of the newborn

a branch to die backwould causea branch to die back

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Smart Reasoning:

C&E

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