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Qaagi - Book of Why

Causes

Effects

His heart ... fillproperly causingdiastolic dysfunction

diastolic heart failure causing pulmonary hypertension and pulmonary hypertensioncausingdiastolic dysfunction

histone deacetylase inhibition , which has shown efficacy in some models of systolic heart failurecould preventdiastolic dysfunction

when the ventricles of the heart are n’t relaxing properly which causes less blood to enter the heart(passive) is causedDiastolic dysfunction

similar circumstances as those of systolic dysfunction(passive) can be caused byDiastolic dysfunction

processes similar to those that cause systolic dysfunction(passive) can be caused byDiastolic dysfunction

TAC / DOCAcausesdiastolic dysfunction

conditions such as hypertension ( causing ventricular hypertrophy(passive) may be caused byDiastolic dysfunction

a drug or a condition(passive) caused bydiastolic dysfunction

the walls ... too thickcausingdiastolic dysfunction

Over time , the remodeling process unfavorably alters LV filling characteristics through impaired relaxation ( in early diastole ) and decreased compliance or increased stiffness ( in mid to late diastoleleadsto diastolic dysfunction [ 3

The disordercausesdiastolic dysfunction

the vessel conduitcausingdiastolic dysfunction

What type of cardiomyopathycausesdiastolic dysfunction

an incomplete relaxation ( stiffness ) of the ventricle muscle , which may develop from untreated high blood pressure(passive) most often is caused byDiastolic dysfunction

underactive thyroid(passive) can be caused byDiastolic dysfunction

ageing , high blood pressure , diabetes , and excessive weight(passive) is often caused byDiastolic dysfunction

the bulging right ventricle(passive) caused bydiastolic dysfunction

lowered left ventricular compliance(passive) caused bydiastolic dysfunction

left ventricular hypertrophy , among others(passive) caused bydiastolic dysfunction

This is useful to diagnose exaggerated hypertensive response to exercisecan causediastolic dysfunction

ischemia and increased tissue doppler velocity ( velocity of myocardial motion(passive) caused bydiastolic dysfunction

hypertension or high blood pressure(passive) usually caused byDiastolic dysfunction

abnormalities in relaxation , increased stiffness or a combination of both(passive) may be caused byDiastolic dysfunction

rigid ventricular walls that impair ventricular stretch and diastolic filling d(passive) caused bydiastolic dysfunction

carfilzomib(passive) caused bydiastolic dysfunction

Obesity and diabetescan triggerdiastolic dysfunction

mechanisms intrinsic to the cardiac muscle cells(passive) can be caused byDiastolic dysfunction

Readcausesdiastolic dysfunction

increased myofilament Ca(2 + ) sensitivity in a mouse model of hypertrophic cardiomyopathy(passive) caused bydiastolic dysfunction

mitochondrial cardiac oxidative stresscan causediastolic dysfunction

Lack of vitamin Dcould causediastolic dysfunction

many determinantscausingdiastolic dysfunction

The histone deacetylase inhibitor ITF2357 ( givinostatpreventsdiastolic dysfunction

abnormalities in left ventricular filling(passive) caused byDiastolic dysfunction

any causes mainly DM and hypertension.[24(passive) caused bydiastolic dysfunction

diminished ventricular compliance , which is strongly influenced by cardiac fibrosis(passive) caused bydiastolic dysfunction

Surgical treatment ... specific diseasecausingdiastolic dysfunction

Infusion of light chains from patients with cardiac amyloidosiscausesdiastolic dysfunction

prolonged [ Ca(2+)](i ) and force transients(passive) caused bydiastolic dysfunction

to a four to eightfold increase in risk for congestive heart failure in diabetic patients ( Piccini et al . , 2004contributesto a four to eightfold increase in risk for congestive heart failure in diabetic patients ( Piccini et al . , 2004

symptoms of heart failurecausessymptoms of heart failure

to up to half of the cases of heart failurecontributesto up to half of the cases of heart failure

in both diastolic and subsequently ... systolic heart failureresultsin both diastolic and subsequently ... systolic heart failure

to diastolic heart failure and how this progression occursdoes ... leadto diastolic heart failure and how this progression occurs

in a stiff ventricle and reduced ventricular filling , or abnormalities to physical structures of the heartresultingin a stiff ventricle and reduced ventricular filling , or abnormalities to physical structures of the heart

to heart failure with preserved ejection fraction ( HFpEFleadingto heart failure with preserved ejection fraction ( HFpEF

to larger E / e ’ ratio , which is explained by the fact that diastolic dysfunction leads to impaired ventricular relaxation , and thus a smaller e ’ waveleadsto larger E / e ’ ratio , which is explained by the fact that diastolic dysfunction leads to impaired ventricular relaxation , and thus a smaller e ’ wave

Exertional dyspnea and a reduced peak maximal oxygen consumption , which are the earliest signs of heart failure in patients with heart valve disease(passive) are often caused byExertional dyspnea and a reduced peak maximal oxygen consumption , which are the earliest signs of heart failure in patients with heart valve disease

to a four- to eightfold increase in the risk of heart failure in diabetic patients , despite preserved LV systolic function ( i.e. , ejection fraction > 50 %contributesto a four- to eightfold increase in the risk of heart failure in diabetic patients , despite preserved LV systolic function ( i.e. , ejection fraction > 50 %

The goal of treatment for CHF(passive) caused byThe goal of treatment for CHF

in increased filling pressures that lead to left atrial enlargement and eventually reduced systolic function with the development of HF symptomsresultingin increased filling pressures that lead to left atrial enlargement and eventually reduced systolic function with the development of HF symptoms

ischemia resulting in systolic dysfunctioncan causeischemia resulting in systolic dysfunction

from high bpcausedfrom high bp

to symptomatologycontributesto symptomatology

in failure probably more prevalent in elderly patients9resultingin failure probably more prevalent in elderly patients9

to left atrial dilatation with consequent atrial fibrillationmay leadto left atrial dilatation with consequent atrial fibrillation

to exacerbation of COPDCan ... leadto exacerbation of COPD

Diastolic dysfunctionHeart failure(passive) caused byDiastolic dysfunctionHeart failure

this type of thecan also causethis type of the

from whiplash injury , epidural or citationmay resultfrom whiplash injury , epidural or citation

from impairment of left ventricular ( LV ) contractile capacity that initiate active suction and effective LV fillingResultsfrom impairment of left ventricular ( LV ) contractile capacity that initiate active suction and effective LV filling

these hemodynamic abnormalities(passive) caused bythese hemodynamic abnormalities

a lack of blood flow to the other organs in the bodycan causea lack of blood flow to the other organs in the body

my pulmonary hypertensionis causingmy pulmonary hypertension

due to abnormalities in the active relaxationcan resultdue to abnormalities in the active relaxation

to systolic failuremay ... leadto systolic failure

pulmonary venous hypertensioncausingpulmonary venous hypertension

to failing Fontan physiologycan contributeto failing Fontan physiology

to an increase in atrial pressures and sizeleadsto an increase in atrial pressures and size

ventricular filling pressure(passive) caused byventricular filling pressure

to increased pressure and fluid in the blood vessels in the lungs ( pulmonary congestioncan leadto increased pressure and fluid in the blood vessels in the lungs ( pulmonary congestion

to defective resolution of inflammationleadingto defective resolution of inflammation

to elevated filling pressure at restmay leadto elevated filling pressure at rest

to elevated left atrial filling pressures which are transmitted to the pulmonary venous systemleadsto elevated left atrial filling pressures which are transmitted to the pulmonary venous system

in increased left ventricular end - diastolic pressure ( LVEDPresultingin increased left ventricular end - diastolic pressure ( LVEDP

Reduced LV filling(passive) caused byReduced LV filling

the edema(passive) is caused bythe edema

to clinical symptoms of moderate to severe AScontributesto clinical symptoms of moderate to severe AS

to hemodynamic instability and adverse outcomes following cardiac surgery ( 5,6may contributeto hemodynamic instability and adverse outcomes following cardiac surgery ( 5,6

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