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Qaagi - Book of Why

Causes

Effects

restrictive cardiomyopathyleadsto diastolic dysfunction ( i. 1

pericardial pressurecausingsevere diastolic dysfunction

Intracellular acidosis induced by ischemic stresscausedsevere diastolic dysfunction

Ischemia / reperfusioncausedsevere diastolic dysfunction

The diseaseresultsin serious diastolic dysfunction

in which the left ventricle becomes too thickgradually resultingin severe diastolic dysfunction

something pathologicalis causingdiastolic dysfunction 2

Diabetes mellitusleadsto an early diastolic dysfunction

dynamicsmay resultin advanced diastolic dysfunction

change LV filling dynamicsmay leadto advanced diastolic dysfunction

Amyloid infiltration of the heartinitially causesmild diastolic dysfunction

impaired LV relaxation with or without reduced restoring forces ( and early diastolic suction(passive) is caused byLV diastolic dysfunction

ventricular ( LV ) hypertrophy is reportedto causeLV diastolic dysfunction

An elevated left atrial pressure with left ventricularcausesLV ) diastolic dysfunction

also cardiac fibrosiscausingLV diastolic dysfunction

by myocardial hypertrophy(passive) caused byLV diastolic dysfunction

Any cardiac diseasecan causeLV diastolic dysfunction

active LV relaxationwill causeLV diastolic dysfunction

by hypertensive ventricular remodeling(passive) caused byLV ) diastolic dysfunction

Left atrial sizeinfluencesLV diastolic dysfunction

Several cardiovascular and systemic diseasescan causeLV diastolic dysfunction

Cardiac involvement in amyloidosiscausesdiastolic LV dysfunction

Severe AScausingLV systolic dysfunction

by diabetes(passive) caused byLV diastolic dysfunction

the disease processcausingLV systolic dysfunction

by Impaired Ventricular Relaxation and Decreased Compliance Diastolic dysfunction of the heart(passive) Caused byDiastolic Dysfunction

the presence of cardiac fibrosis ... abnormal myocardial stiffnesscontributesto diastolic dysfunction

Due to increases in left ventricular pressure from the stenotic aortic valve , over time the ventricle may hypertrophyresultingin diastolic dysfunction

Due to increases in left ventricular pressure from the stenotic aortic valve , over time the ventricle may hypertrophyresultingin a diastolic dysfunction

processes similar to those that cause systolic dysfunction particularly causes that affect cardiac remodeling(passive) can be caused byDiastolic dysfunction

cardiac hypertrophy and fibrosisleadingto diastolic dysfunction

left ventricular pressure ] ] from the stenotic aortic valve , over time the ventricle may hypertrophyresultingin a diastolic dysfunction

conditions such as hypertension ( causing ventricular hypertrophy(passive) may be caused byDiastolic dysfunction

significant alterations in myocardial tissue architecture ( increased interstitial matrixresultedin diastolic dysfunction

increased LV diastolic pressuresresultingfrom diastolic dysfunction

by increased ventricular stiffness(passive) caused bydiastolic dysfunction

the infusion of light chains from patients with cardiac amyloidosiscausesdiastolic dysfunction

Infusion of light chains from patients with cardiac amyloidosiscausesdiastolic dysfunction

systolic function ... impaired LV complianceresultsin diastolic dysfunction

systolic function with impaired LV complianceresultsin diastolic dysfunction

HFPEF in thirty percent of patientscausesHFPEF in thirty percent of patients

erectile dysfunction medicine needsdoes ... causeerectile dysfunction medicine needs

to heart failurecan leadto heart failure

to heartcan leadto heart

decreased relaxationcausesdecreased relaxation

to elevated pulmonary pressuresleadingto elevated pulmonary pressures

to pulmonary hypertension and heart failureleadingto pulmonary hypertension and heart failure

to heart failuremay leadto heart failure

to diastolic heart failurecan leadto diastolic heart failure

to the increasedcontributeto the increased

heart failurecausingheart failure

congestive heart failure ( CHF(passive) caused bycongestive heart failure ( CHF

to the increased mortality risk observed in HF patients with renal dysfunctioncontributeto the increased mortality risk observed in HF patients with renal dysfunction

to ventricular dilationhas ledto ventricular dilation

to congestive heart failureleadsto congestive heart failure

to heart failure ( HFleadingto heart failure ( HF

to more pulmonary hypertensionleadingto more pulmonary hypertension

to heart failure with preserved ejection fraction ( HFpEFleadingto heart failure with preserved ejection fraction ( HFpEF

to high filling pressuresleadingto high filling pressures

from impaired relaxation and filling of the stiff and hypertrophied left ventricle ( often associated with increased filling pressuresresultingfrom impaired relaxation and filling of the stiff and hypertrophied left ventricle ( often associated with increased filling pressures

from impaired relaxation and filling of the stiff and hypertrophied left ventricleresultingfrom impaired relaxation and filling of the stiff and hypertrophied left ventricle

to pulmonary hypertension and heart failureleadingto pulmonary hypertension and heart failure

LA enlargement(passive) caused byLA enlargement

the testes i normal size and function the anatomy and functioncausesthe testes i normal size and function the anatomy and function

to these resultsmay contributeto these results

heart failurecan ... causeheart failure

to a 13 percent reduction in all - cause mortality , a 2016 study in The Lancet foundcan leadto a 13 percent reduction in all - cause mortality , a 2016 study in The Lancet found

from slow LV relaxation and increased LV stiffnessresultingfrom slow LV relaxation and increased LV stiffness

pulmonary venous hypertensioncausingpulmonary venous hypertension

to heart failuremay leadto heart failure

further to elevated LA pressure 3contributesfurther to elevated LA pressure 3

heart failure(passive) caused byheart failure

the left atrium ( LA ... and causes LA enlargementinfluencesthe left atrium ( LA ... and causes LA enlargement

mitral annular dilationcausingmitral annular dilation

to congestive heart failureleadsto congestive heart failure

to both an increase in the ventricular pressure and a decrease in the end - diastolic volumeleadsto both an increase in the ventricular pressure and a decrease in the end - diastolic volume

from myocardial relaxation and ventricular compliance abnormalities that lead to an increase in LV end - diastolic pressureresultsfrom myocardial relaxation and ventricular compliance abnormalities that lead to an increase in LV end - diastolic pressure

to impaired systolic function and eventually heart failurecan leadto impaired systolic function and eventually heart failure

Diastolic dysfunction Heart failure(passive) caused by Diastolic dysfunction Heart failure

in a decrease in ventricular compliance with elevation in left ventricular diastolic and pulmonary venous pressureresultingin a decrease in ventricular compliance with elevation in left ventricular diastolic and pulmonary venous pressure

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