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Qaagi - Book of Why

Causes

Effects

Deficiency of alpha-1,4-glucosidasemay causeGLYCOGEN STORAGE DISEASE TYPE II.Hexosaminidases

a deficiency of muscle phosphofructokinase and characterized by muscular weakness(passive) caused byPFKM A glycogen storage disease

a deficiency in liver glycogen phosphorylase or other components of the associated phosphorylase cascade system.[2(passive) caused byglycogen storage disease

PreventionThere ... no simple wayto preventglycogen storage disease

a deficiency of acid alpha - glucosidase ( GAA(passive) caused bya glycogen storage disease

genetic defects that results in deficiency in certain enzymes of glycogen metabolism(passive) are caused byGlycogen Storage diseases

the lack of an enzyme needed to change glucose into glycogen and break down glycogen into glucose(passive) are caused byGlycogen storage diseases

Mutations in the glucose-6-phosphatase genecauseglycogen storage disease 1a

other problems ... no wayto preventglycogen storage disease

a deficiency of the lysosomal enzyme , acid maltase / acid α-1,4 glucosidase ( GAA(passive) caused bya glycogen storage disease

Abstract : Muscle - specific deficiency of phosphorylase kinase ( Phkcausesglycogen storage disease

a deficiency of the enzyme a-1,4-glucosidase(passive) caused bya lysosomal glycogen storage disease

a deficiency in acid α - glucosidase ( GAA ) , a hydrolase necessary for the degradation of lysosomal glycogen(passive) caused bya glycogen storage disease

516–526 ( 2003 ) | Download Citation Muscle - specific deficiency of phosphorylase kinase ( Phkcausesglycogen storage disease

a rare deficiency in glucose-6-phosphatase or in amylo-1,6-glucosidase(passive) is caused byGlycogen storage disease

mutations in the PYGM gene encoding myophosphorylase(passive) caused bya glycogen storage disease

myophosphorylase deficiency(passive) caused bya glycogen storage disease

a genetically induced deficiency of the enzyme glucose-6-phosphatase(passive) caused byglycogen storage disease

a genetic deficiency of one or another of the enzymes of glycogen metabolism(passive) are caused byGlycogen storage diseases

an inherited deficiency in myophosphorylase , an enzyme that initiates the breakdown of muscle glycogen for glycolysis(passive) caused bya glycogen storage disease

a deficiency of lysosomal a - glucosidase(passive) caused byA glycogen storage disease

deficiency in a ( 1 4(passive) caused bySevere glycogen storage disease

Carlie Rider Etiology of GSD(passive) Created byGlycogen Storage Disease

α-1,4 glycosidase ( acid maltase deficiency ) in infants(passive) caused bya glycogen storage disease

At least 85 mutations in the G6PC gene have been foundto causeglycogen storage disease type

Deficiencies in PFK activitycan resultin the glycogen storage disease

apart from enzyme deficienciesmay leadto glycogen storage disease

Mao - Sen Sun , C Q Pan , +6 authors Janice Y Chou Deficiency of glucose-6-phosphatase ( G6Pase ) , a key enzyme in glucose homeostasiscausesglycogen storage disease type

glucose-6-phosphatase deficiency(passive) caused byglycogen storage disease

a deficiency [ en.wikipedia.org(passive) caused byglycogen storage disease

deficiency of cardiac phosphorylase kinase(passive) caused byglycogen storage disease

acid alfa - glucosidase deficiency(passive) caused bya glycogen storage disease

acid α - glucosidase deficiency(passive) caused bylysosomal glycogen storage disease

Muscle - specific deficiency of Phkcausesglycogen storage disease

a deficiency of the lysosomal enzyme , acid maltase / acid alpha-1,4 glucosidase ( GAA(passive) caused bya glycogen storage disease

a deficiency in alpha-1,4-glucan(passive) caused byglycogen storage disease

acid α - glucosidase enzyme deficiency(passive) caused bya glycogen storage disease

GLUCAN 1,4-ALPHA - GLUCOSIDASE deficiency(passive) caused byglycogen storage disease

an enzyme deficiency that prevents glycogenolysis and release of glucose into the circulation(passive) are caused byGlycogen storage diseases

deficiency of amylo-1,4 - 1,6 transglucosidase(passive) caused byglycogen storage disease

uric acid ( a waste product ) to accumulate in the joints , which can cause gout ( see Goutto causeuric acid ( a waste product ) to accumulate in the joints , which can cause gout ( see Gout

low blood sugar levelscauselow blood sugar levels

Melanie to have low blood sugarcausesMelanie to have low blood sugar

uric acid ( a waste product ) to accumulate in the joints , which can cause gout , and in the kidneys , which can cause kidney stonesto causeuric acid ( a waste product ) to accumulate in the joints , which can cause gout , and in the kidneys , which can cause kidney stones

in enlarged livers and low blood sugar Jan 27 , 2015can resultin enlarged livers and low blood sugar Jan 27 , 2015

persons with hypoglycemia(passive) caused bypersons with hypoglycemia

hepatosplenomegaly and failure to thrive Aguecheek diseasecausinghepatosplenomegaly and failure to thrive Aguecheek disease

accumulation of glycogen on cardiac tissuescausesaccumulation of glycogen on cardiac tissues

the body from using sugars properlypreventthe body from using sugars properly

hepatomegaly , cardiomegaly , muscle hypotonia , and deathcauseshepatomegaly , cardiomegaly , muscle hypotonia , and death

from known defects in glycogenolysis , glycolysis , and glycogen synthesis that have been described in humans and domestic animalsresultingfrom known defects in glycogenolysis , glycolysis , and glycogen synthesis that have been described in humans and domestic animals

in hypoglycemia and glycogen buildup in the liver that interferes with fat metabolismresultingin hypoglycemia and glycogen buildup in the liver that interferes with fat metabolism

glucose to build up in the body , leading to serious health issuescausesglucose to build up in the body , leading to serious health issues

the body to stop process glycogen , which is a sugar converted to glucose and is used by the body as energycausesthe body to stop process glycogen , which is a sugar converted to glucose and is used by the body as energy

to glycogenesis ( many typesleadsto glycogenesis ( many types

from enzyme deficiencies involving the glycolytic pathwayresultfrom enzyme deficiencies involving the glycolytic pathway

from the inability to properly metabolize glycogenresultfrom the inability to properly metabolize glycogen

filter results by(passive) are causedfilter results by

from genetically inherited deficiencies in enzymes required for glycogen synthesis or catabolismresultfrom genetically inherited deficiencies in enzymes required for glycogen synthesis or catabolism

glycogen to be stored every where - including the heart Compare and contrast dystrophic calcification with metastatic calcificationcausesglycogen to be stored every where - including the heart Compare and contrast dystrophic calcification with metastatic calcification

from the faulty processing of glycogen , which is a form of carbohydrateresultingfrom the faulty processing of glycogen , which is a form of carbohydrate

to glycogen deficiencyleadingto glycogen deficiency

glycogen ... the stored form of glucosepreventglycogen ... the stored form of glucose

GSD ) type IVcausesGSD ) type IV

from at least 10 different genetic defects in proteins required by glycogen metabolismresultfrom at least 10 different genetic defects in proteins required by glycogen metabolism

PGM1 ... Congenital disorder of deglycosylation 615273 ; Glycogen storage disease type XIV ( Glycogen storage disorders ) ; Congenital disorder of glycosylation , type It , 614921 ; Glycogen Storage Disorders- Muscle ; Glycogen Storage Disease Type XIV ; Glycogen storage disease XIV , 612934(passive) were setPGM1 ... Congenital disorder of deglycosylation 615273 ; Glycogen storage disease type XIV ( Glycogen storage disorders ) ; Congenital disorder of glycosylation , type It , 614921 ; Glycogen Storage Disorders- Muscle ; Glycogen Storage Disease Type XIV ; Glycogen storage disease XIV , 612934

from deficiencies in the enzymes that build glycogen , as well as those that interfere with the degradation of glycogen and subsequent mobilization of glucoseresultfrom deficiencies in the enzymes that build glycogen , as well as those that interfere with the degradation of glycogen and subsequent mobilization of glucose

from the congenital absence of various enzymesresultfrom the congenital absence of various enzymes

her to be hypoglycemiccausesher to be hypoglycemic

This was suspected(passive) to be caused byThis was suspected

to low glucose levels creating a metabolic condition known as reactive hypo - glycemiamay contributeto low glucose levels creating a metabolic condition known as reactive hypo - glycemia

to heart failuremay eventually leadto heart failure

Type 4causesType 4

GYS2 ... Glycogen storage disease , type 0 , 240600 ; fasting intolerance without enlarged liver(passive) were setGYS2 ... Glycogen storage disease , type 0 , 240600 ; fasting intolerance without enlarged liver

typicallycausetypically

PHKA2(passive) were setPHKA2

FSGS [ 40 , 41to causeFSGS [ 40 , 41

muscle weakness and exercise intolerance in young dogs and catscan causemuscle weakness and exercise intolerance in young dogs and cats

from a genetic enzyme deficiencyresultingfrom a genetic enzyme deficiency

to weakness , stiffness , exercise intolerance and difficulty swallowingcan leadto weakness , stiffness , exercise intolerance and difficulty swallowing

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