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Qaagi - Book of Why

Causes

Effects

Leachables from plastic consumables like pipette tipscan causeghost peaks in HPLC

a variety of factorscan causeghost peaking

When I operated an instrument on a daily basis , it was only a matter of timecausedghost peaks in my chromatogram

The hiring manager asked memay be causinga tailing peak in HPLC

Pollutants in the gasescan causeghost peaks in the chromatogram

The discharge of a total flooding gaseous fire extinguishing system into an enclosurecreateslarge peak In HPLC

the multi - coupling interference common in traditional white light interferometers ... both of whichcan causeghost ” peaks in the measured signal

your mobile phasecausinga ghost peak

the silanolscausepeak tailing in HPLC

to be elutedresultingin the ghost peak

The interference(passive) caused byThe interference

errors in identification of the actual coupling points x1 , x2 and x3can ... causeerrors in identification of the actual coupling points x1 , x2 and x3

to wrong key corresponding to the target Sboxleadsto wrong key corresponding to the target Sbox

from the organic solventoriginatingfrom the organic solvent

to diagnostic dilemma and delay in treatmentledto diagnostic dilemma and delay in treatment

from oxidation of aged TFAmay resultfrom oxidation of aged TFA

inconsistent and inaccurate impurity resultscan causeinconsistent and inaccurate impurity results

from space charge and non - linear fields in an ion trap mass spectrometerresultingfrom space charge and non - linear fields in an ion trap mass spectrometer

from atmospheric contaminationoriginatingfrom atmospheric contamination

from the mobile phaseresultingfrom the mobile phase

for example a. Crystallinecreatingfor example a. Crystalline

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