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Smart Reasoning:

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Qaagi - Book of Why

Causes

Effects

any drugcausingGERM CELL CANCER

a possibilitycould causeGerm Cell Cancer

ETOPOSIDE ... other drugscauseGERM CELL CANCER

when they become large , palpable masses(passive) are typically discovered16 Germ - cell tumors

a potentialto causetumor cell damage[73

casemay leadto testicular germ cell tumor

mutations ... a germ cellleadsto a germ cell tumor

primarily of testicular neoplasms as well as ovarian and extragonadal germ cell tumors ( no primary tumor in either testis or ovary(passive) are composedGERM CELL TUMORS Germ cell tumors

primarily of testicular neoplasms as well as ovarian and extragonadal germ - cell tumors ( no primary tumor in either testis or ovary(passive) are composedGerm - cell tumors

This mutationleadsto germ cell tumors

by multiple cell types(passive) are ... composedGerm cell tumors

by multiple cell types(passive) are ... composed byGerm cell tumors

Most testicular cancersoriginateas germ cell tumors

The symptomsleadingto germ cell tumors

typically(passive) are ... discoveredGerm - cell tumors

the hypothesismay contributeto germ cell tumor progression

Stem cell self - renewal at the expense of differentiationcan causegerm cell tumors

when they become large , palpable masses(passive) are typically discoveredGerm - cell tumors

when Ashkenazi Jewsbecome large , palpable masses(passive) are typically discoveredGerm - cell tumors

AFP ( IU / mL ) or ng / mL ... a very high concentration of AFPmay leadto germ cell tumor

their abilityto influencethe?survival of tumor cells

Regulation of cell motility ... by whichinfluencestumor cell metastasis

Regulation of cell motility ... by whichinfluencestumor cell metastasis

the tumor microenvironmentcan influencetumor cell dissemination.4

Bmi1 deficiency(passive) caused bygerm cell apoptosis

by which topoisomerase inhibitorscausetumor cell cytotoxicity

these effectsdo ... causetumor cell cytotoxicity

In generalcan influencegerm cell apoptosis

CAS / Crk signalingmay ... influencetumor cell metastasis

C ) Fully activated CARs attack target cellscausingtumor cell lysis

therapy with allopurinol ( allopurinol sodium ) for Injection ... knownto causetumor cell lysis

The virus ... tumor cellscausestumor cell lysis

accessory cells formto causetumor cell lysis

In presence of ertumaxomab , tri - cell complexes consisting of tumor cells , T cells , and accessory cells formto causetumor cell lysis

selectively infects and replicates in tumor cellseventually causingtumor cell lysis

an immune responsecausingtumor cell lysis

antigenscausingtumor cell lysis

the cytotoxic granulesmay causetumor cell lysis

The over - expression ofcontributesBcl-2 in tumor cells

MMP9 mediates matrix degradationcausingtumor cell spreading

Germ cell tumor chestcausesGerm cell tumor chest

of multiple tissues , including tissues not normally found in the organ in which it arisescomposedof multiple tissues , including tissues not normally found in the organ in which it arises

of multiple tissues , including tissues not normally found in the organ in which it arisescomposedof multiple tissues , including tissues not normally found in the organ in which it arises

from the cells of the reproductive systemsoriginatefrom the cells of the reproductive systems

from a failure of germ cells to migrate properly intypically resultingfrom a failure of germ cells to migrate properly in

from germ cellsoriginatedfrom germ cells

from primordial germmay originatefrom primordial germ

from primordial germ cellsoriginatefrom primordial germ cells

acute pancreatitiscausedacute pancreatitis

within the egg cellsoriginatewithin the egg cells

issues due to their size or locationmay causeissues due to their size or location

issues due to their size or locationcould causeissues due to their size or location

of differentiated , adult - type tissuescomposedof differentiated , adult - type tissues

of teratoma with malignant areacomposedof teratoma with malignant area

of teratoma ( 50 %was composedof teratoma ( 50 %

mostly of immature teratomacomposedmostly of immature teratoma

of cells recapitulating the three germ cell layerscomposedof cells recapitulating the three germ cell layers

in germ cellsoriginatingin germ cells

of immature teratoma with malignant transformation ( 70 %mainly composedof immature teratoma with malignant transformation ( 70 %

from germ cells in the ovaryoriginatefrom germ cells in the ovary

from pluripotent germ cellsoriginatesfrom pluripotent germ cells

of spindle cellscomposedof spindle cells

mostly of immature teratoma with a minor component of yolk sac tumorcomposedmostly of immature teratoma with a minor component of yolk sac tumor

from cells that form eggsoriginatefrom cells that form eggs

of elements from one or more of the embryonic germ layerscomposedof elements from one or more of the embryonic germ layers

in the anterior mediastinumoriginatein the anterior mediastinum

of seminoma , choriocarcinoma and teratoma with a secondary somatic malignancycomposedof seminoma , choriocarcinoma and teratoma with a secondary somatic malignancy

of multiple cell types derived from one or more of the three germ cell layerscommonly composedof multiple cell types derived from one or more of the three germ cell layers

of multiple cell types derived from one or more of the 3 germ layerscommonly composedof multiple cell types derived from one or more of the 3 germ layers

of multiple cell types derived from one or more of the 3 germ layersmainly composedof multiple cell types derived from one or more of the 3 germ layers

inside the ovaries in the cells that create the eggsoriginateinside the ovaries in the cells that create the eggs

inside the ovaries in the cells that create the eggsoriginateinside the ovaries in the cells that create the eggs

of multiple cell varieties derived from a number of of the three germ layerscommonly composedof multiple cell varieties derived from a number of of the three germ layers

of a tridermic testicular teratoma and seminomacomposedof a tridermic testicular teratoma and seminoma

alsomay ... originatealso

of tubules and cystscomposedof tubules and cysts

from the cells of an embryos gonadsoriginatefrom the cells of an embryos gonads

in the brainoriginatein the brain

currentcausescurrent

the formcan leadthe form

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