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Qaagi - Book of Why

Causes

Effects

the duplicated cxcr4a / bshould resultfrom the teleost - specific genome duplication ( Ts3R

chromosomal regions or entire chromosomes , or genome - wide eventsresultin complete genome duplication ( polyploidization

chromosomal regions or entire chromosomes , or genome - wide eventsresultin complete genome duplication

Origin and Evolution of Redundant Genes Gene redundancymost often resultsfrom Gene duplication

Definition Genes ... , and so are found in more than one copy in the same genomeresultfrom gene duplication

45 Chromosome - level mutationsCan causegene duplication

a mutationcausesgene duplication

Types of mutationcausesGene duplication

mutationscan causegene duplication

Two copies of the POMC gene were previously identified , A and Bpresumably resultingfrom the salmonid genome duplication

mutationscauseduplication of genes

Random mutationcan causeduplication of genes

Two fundamental techniquesmight causeduplication of genes

a potential second Nr4a2 generesultingfrom the teleost genome duplication

origin - independent , recombination - directed replication initiationcontributesto Leishmania genome duplication

the two copiesresultfrom genome duplication

gene duplicatesoriginatingfrom whole genome duplication ( WGD

DNA(passive) could be caused byGenome duplication

then the normal process of chromosomal segregationcausinggenome duplication

the duplicate copiesresultingfrom the genome duplication

some calpain genesresultfrom genome duplication

Some of them might interfere in the normal process of chromosomal segregationcausinggenome duplication

Such repetitive sequence elementscan causegenome rearrangements

wholecan resultgenome duplication

polyploidization event(passive) caused bygenome duplication

by polyploidization event(passive) caused bygenome duplication

My Copy Abstract Polyploidizationresultsin genome duplication

that these paralogs have been retainedoriginatedby genome duplication

Polyploidizationresultsin genome duplication

support for zebrafish dscam and sdk2 paralogshaving originatedduring the teleost genome duplication

S. cerevisiae twin ORFsoriginatefrom the genome duplication

interstitial telomeric sequences in yeast(passive) caused byGenome rearrangements

the duplicate copies of PRR5 , PRR7 and PRR9 ,originatedin a genome duplication

Or , it may be treated erroneously as a separate chromosomecausingchromosomal duplication]].

may be treated erroneously as a separate chromosomecausingchromosomal duplication

Or , it may be treated erroneously as a separate chromosomecausingchromosomal duplication

Or , it may be treated erroneously as a ccausingchromosomal duplication

of 11 segments of double - stranded RNA , six structural coding for proteins(passive) is composedGenome

duplicated genesoriginatingfrom whole genome duplication

Gene duplicatesresultingfrom the whole genome duplication

to the doubling of many genesledto the doubling of many genes

to paralogous genesleadingto paralogous genes

to a diversification in the CPThave leadto a diversification in the CPT

to a sizable expansion of the MADS - box family of transcription factorshave ledto a sizable expansion of the MADS - box family of transcription factors

to individuals with two copies of a gene where in their ancestors there was only oneoccasionally leadsto individuals with two copies of a gene where in their ancestors there was only one

in two or more copies of a generesultsin two or more copies of a gene

in gene familiescan ... resultin gene families

to mutation and certain disordersmay leadto mutation and certain disorders

to the abundance of metabolic genes in the moss * Physcomitrella patenscontributedto the abundance of metabolic genes in the moss * Physcomitrella patens

to new biological informationleadsto new biological information

to two different forms of QPT geneleadsto two different forms of QPT gene

to redundancyleadsto redundancy

to phenotypic changesmay have contributedto phenotypic changes

to power - law distributionscan leadto power - law distributions

to HER2 overexpression in 25 percent of breast cancer patients and developed a drug called Herceptin ( trastuzumabledto HER2 overexpression in 25 percent of breast cancer patients and developed a drug called Herceptin ( trastuzumab

This phenomenon(passive) might be caused byThis phenomenon

to divergence of one geneledto divergence of one gene

to an expansion of gene families and the development of specialized genesledto an expansion of gene families and the development of specialized genes

to genomic instability and death of the cellcan leadto genomic instability and death of the cell

in every chromosome being duplicatedresultsin every chromosome being duplicated

to the large genome sizedid ... contributeto the large genome size

to new chemical diversity in plantscan leadto new chemical diversity in plants

to genomic changes between ploidy levelscan rapidly leadto genomic changes between ploidy levels

to phenotypic changesmay have contributedto phenotypic changes

in significantly attenuated phenotypesresultingin significantly attenuated phenotypes

to humanhas contributedto human

to highledto high

to highly selective expansion of the Arabidopsis thalianaledto highly selective expansion of the Arabidopsis thaliana

from the CRoriginatingfrom the CR

to highly selective expansion of the Arabidopsis thaliana proteomeledto highly selective expansion of the Arabidopsis thaliana proteome

organization(passive) caused byorganization

in polyploidyresultsin polyploidy

up to mammalsleadingup to mammals

to speciation ( the formation of new species ) and evolution of complexity by two main mechanisms : neofunctionalization and subfunctionalizationleadsto speciation ( the formation of new species ) and evolution of complexity by two main mechanisms : neofunctionalization and subfunctionalization

to highly selective expansion of theArabidopsis thaliana proteomeledto highly selective expansion of theArabidopsis thaliana proteome

to a similar increase in different rice cultivars in terms of soluble sugar accumulation under salt stressledto a similar increase in different rice cultivars in terms of soluble sugar accumulation under salt stress

chromosomal instability and tolerance to mitotic errorscauseschromosomal instability and tolerance to mitotic errors

in increased copy number of genes encoding the sister chromatid cohesion complex conveys clinical consequences distinct from Cornelia de Langeresultingin increased copy number of genes encoding the sister chromatid cohesion complex conveys clinical consequences distinct from Cornelia de Lange

to the formation of gene familiescan contributeto the formation of gene families

in expansions of gene families leading to metabolic diversity over evolutionary timehas resultedin expansions of gene families leading to metabolic diversity over evolutionary time

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