to prostate cancer disparitiescontributeto prostate cancer disparities

to prostate cancer disparities in men of African descentcontributeto prostate cancer disparities in men of African descent

to the differences in disease risks and drug responses amongst different individualsmay contributeto the differences in disease risks and drug responses amongst different individuals

to phenotypic differences amongst individuals , including disease risk and drug responsecan contributeto phenotypic differences amongst individuals , including disease risk and drug response

to overweight issueleadsto overweight issue

to the low DNA repair capacity and to the variants associated with detoxification capacity reduction , in which mutations are responsible for the increasing susceptibility to such damagesmay contributeto the low DNA repair capacity and to the variants associated with detoxification capacity reduction , in which mutations are responsible for the increasing susceptibility to such damages

to altered expression and function of the protein in the placentaleadingto altered expression and function of the protein in the placenta

in altered gene expression or functional changes of the encoded moleculesmay resultin altered gene expression or functional changes of the encoded molecules

alsocausealso

toward interindividual variations in drug responsecontributetoward interindividual variations in drug response

the risk of MM and the response to cisplatin based MM treatmentinfluencethe risk of MM and the response to cisplatin based MM treatment

drug response and its clinical applicationsinfluencingdrug response and its clinical applications

phenotypic variation in this processcan causephenotypic variation in this process

individual susceptibilitymay influenceindividual susceptibility

in DECREASED activity of this enzymeresultin DECREASED activity of this enzyme

disease severityalso influencedisease severity

metabolic enzyme levelsinfluencemetabolic enzyme levels

to a breast cancer riskcontributingto a breast cancer risk

B7-H1 expression modify cancer susceptibilityinfluencingB7-H1 expression modify cancer susceptibility

heart failurecausingheart failure

to important interindividual differences in the capacityleadto important interindividual differences in the capacity

in altered responsiveness in drug targets ( e.g. receptor function ... or altered drug handling ( e.g. enzyme activitycan resultin altered responsiveness in drug targets ( e.g. receptor function ... or altered drug handling ( e.g. enzyme activity

drug metabolisminfluencingdrug metabolism

the risk of MM and the response to cisplatin basedinfluencethe risk of MM and the response to cisplatin based

in a reduced functionresultingin a reduced function

to the patient 's variability in response to opioid treatmentmay ... contributeto the patient 's variability in response to opioid treatment

to interindividual variability in metabolism ratescontributeto interindividual variability in metabolism rates

to the variability of clopidogrel response in patients with Coronary Artery Disease ( CADcontributingto the variability of clopidogrel response in patients with Coronary Artery Disease ( CAD

large inter - individual variability in CYP2D6 enzyme activitycauselarge inter - individual variability in CYP2D6 enzyme activity

variable responses ( normal , intermediate , and low activity ) to thiopurine metabolismcausesvariable responses ( normal , intermediate , and low activity ) to thiopurine metabolism

risk for asthmado ... influencerisk for asthma

to production traits of interestcontributingto production traits of interest

in susceptibility to these disorders in human populationsresultin susceptibility to these disorders in human populations

the pharmacokinetic variability between individualsinfluencethe pharmacokinetic variability between individuals

in reduced LDL - C levelsresultin reduced LDL - C levels

This variation(passive) is usually caused byThis variation

to differential symptom susceptibilitymay contributeto differential symptom susceptibility

to reduced enzyme activity , such as those homozygous for wayleadto reduced enzyme activity , such as those homozygous for way

in deficiency of this enzyme in some populations ( e.g. , Japanese and Native Americansmay resultin deficiency of this enzyme in some populations ( e.g. , Japanese and Native Americans

T - cell activation modify cancer susceptibilityinfluencingT - cell activation modify cancer susceptibility