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a ) Repair by NHEJ usually results in the insertion ( green ) or deletion ( red ) of random base pairscausinggene knockout by disruption
A non - ribosomal peptide synthetaseresultedNRPS ) gene knockout experiment
both hormonal and genetic elementscausesgene regulation.[16
In the context of genome - wide LOF screens , the aim isto causegene disruption and knockout
The T - DNA insertioncausesa knockout expression from the gene
usually(passive) is ... causedGene move
Successful editing at the DNA leveldoes ... leadto functional gene knockout
ableto causegene knockdown[32
named RNA interference ( RNAi(passive) was discoveredgene knockdown
DNAworks ( http://helixweb.nih.gov/dnaworks/ ... and synthetized by Genscript , Nanjing , China(passive) was designed bygene ( pel168s
sirna ... from whichoriginatedgene knockdown
If the ZFN - induced cleavage event is resolved via non - homologous end joining , this can result in small deletions or insertionseffectively leadingto gene knockout
of 3 names(passive) is composedGene LeBell
However the box office performance of Katzman 's action movies and serials , particularly Superman was outstripping those for Gene Kupra's musicals and comediesleadingGene Kupraaway
to mRNA , pre / matureto causegene knockdown
One repair mechanismwill resultin gene knockout
this DNA break ... the cellcan resultin gene knockout
an insertion mutationleadsto gene knockout
polar effectsresultingfrom insertional gene knockout
a specific site ( locus ) in the yeast genomewill ... causea knockout of that gene
Subsequent cleavage events via the fused endonuclease can then lead to either incomplete repair by NHEJleadingto gene knockout
genesresultsin gene - knockout
sequence deletionsleadingto gene knockout
a mutant allele ... which , however , was not expected ... and a second in frameto causethe knockout of the gene
frameshift mutationsleadingto gene knockout
frame - shift mutationsresultingin gene knockout
to expose double - strand breaks at the chosen target site of the host genomeleadingto gene - knockout
the yeast genomewill ... causea knockout of that gene
a mutant allele ... which , however , was not expectedto causethe knockout of the gene
the T - DNA insertion in NAC002causedknockout of gene expression
a toolis ... designedfor gene knockout
The formercan leadto gene knockout
Endogenous repair mechanisms triggered by the double - strand breakmay resultin gene knockout
the indel that is more likelyto resultin knockout of the gene
This process ... errorsresultin a gene knockout
not only an in - del mutationleadingto gene knockout
their native functionsthus resultingin the knockout of the gene
The insertion of a TE into an exonresultsin a gene knockout
by multiple population genetic parameters , such as population sizes(passive) is influenced byGene lineages
a frameshiftmay leadto gene knockout
accumulation of G6P(passive) caused byaccumulation of G6P
the transcript level of cyoA to be up - regulatedcausedthe transcript level of cyoA to be up - regulated
cyoA transcript level to be up - regulated under both N- rich and N- limiting conditionscausedcyoA transcript level to be up - regulated under both N- rich and N- limiting conditions
in discoloration of calliresultedin discoloration of calli
in the discoloration of calliresultedin the discoloration of calli
destruction of intestinal structure and animal death in micecausesdestruction of intestinal structure and animal death in mice
complex intracellular changes associated with stress response and cell deathcausescomplex intracellular changes associated with stress response and cell death
the transcript level of cydB gene to be up - regulated , and those of other respiratory chain genes such as nuoA , ndh , and atpA genes were also up - regulated ( p < 0.01 , p < 0.01 , and p < 0.01 , respectivelycausedthe transcript level of cydB gene to be up - regulated , and those of other respiratory chain genes such as nuoA , ndh , and atpA genes were also up - regulated ( p < 0.01 , p < 0.01 , and p < 0.01 , respectively
the expression of neighbouring genescan influencethe expression of neighbouring genes
to muscle , eye , and RNAleadsto muscle , eye , and RNA
subtle immune deficiencies ... despite the fact that the mice are overall healthy ( 31causessubtle immune deficiencies ... despite the fact that the mice are overall healthy ( 31
the increase in glycolysis fluxcausesthe increase in glycolysis flux
the cells to slow downcausesthe cells to slow down
the transcript level of cydB gene to be up - regulated ... while cydB gene knockout caused cyoA transcript level to be up - regulated under both N- rich and N- limiting conditionscausedthe transcript level of cydB gene to be up - regulated ... while cydB gene knockout caused cyoA transcript level to be up - regulated under both N- rich and N- limiting conditions
to elevated postnatal mortalityleadsto elevated postnatal mortality
destruction of intestinal structure and animal deathcausesdestruction of intestinal structure and animal death
an early gastrulation defectcausesan early gastrulation defect
in complete loss of resistanceresultedin complete loss of resistance
Virus replicationinfluencesVirus replication
in absence or malformation of eyesresultedin absence or malformation of eyes
a cell to lose its apoptotic powerswill causea cell to lose its apoptotic powers
to cardiovascularledto cardiovascular
the increase in glycolysis flux , and thus EIIA - P decreases and in turn cAMP - Crp decreasescausesthe increase in glycolysis flux , and thus EIIA - P decreases and in turn cAMP - Crp decreases
diseases(passive) caused bydiseases
in the lossresultin the loss
evolutionaryHave ... causedevolutionary
evolutionary reversals in the mammalian first archHave ... causedevolutionary reversals in the mammalian first arch
to targeted overproductionsleadingto targeted overproductions
the failure of many structures to form , such as the isthmic nuclei , the cerebellum , motor nerve V and many other derivatives of rhombomeres 1 - 3causesthe failure of many structures to form , such as the isthmic nuclei , the cerebellum , motor nerve V and many other derivatives of rhombomeres 1 - 3
in resistance to the BRAF protein kinase inhibitor vemurafenib ( PLX ) in melanoma ( 16resultin resistance to the BRAF protein kinase inhibitor vemurafenib ( PLX ) in melanoma ( 16
energy balance regulating peptides in the hypothalamic paraventricular and supraoptic nucleiinfluencesenergy balance regulating peptides in the hypothalamic paraventricular and supraoptic nuclei