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Smart Reasoning:

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Qaagi - Book of Why

Causes

Effects

the chainmay have originateda result of gene duplication

mutationsdo ... causegene duplication that is beneficial

The transcriptional changes affecting one or both of the gene copiesresultingfrom gene duplication

the cytidine deaminase gene familyis one of seven related genes or pseudogenes found in a cluster , thoughtto resultfrom gene duplication

It is one of seven related genes or pseudogenes found in a cluster thoughtto resultfrom gene duplication

New functional genesresultingfrom gene duplication

the polynucleotide cytosine deaminase gene familyis one of seven related genes or pseudogenes found in a cluster , thoughtto resultfrom gene duplication

Origin and Evolution of Redundant Genes Gene redundancymost often resultsfrom Gene duplication

multiple genesresultingfrom gene duplication

Paralogous genes ... a speciesresultfrom gene duplication

the gene copiesresultingfrom gene duplication

Some new genesoriginateby gene duplication

those three genesresultedfrom gene duplication

A duplication mutationcausesduplication of this gene

e.g. the two sequencesresultfrom a gene duplication

to cause XX male sex reversal(passive) has also been discoveredA duplication of the SOX3 gene

Paralogous genesresultfrom gene duplication

Paralogous genes resultfrom gene duplication

In paralogous genesresultsfrom gene duplication

paralogous genesresultingfrom gene duplication

the timewhen ... was inventedgene splicing

Definition Genes ... , and so are found in more than one copy in the same genomeresultfrom gene duplication

it has been suggestedoriginatefrom an intrachromosomal gene duplication

the two sequencesresultfrom a gene duplication

Multiple mechanismscontributeto gene duplication

45 Chromosome - level mutationsCan causegene duplication

the nucleus - located SSL genes in Brassicaceae ... a new member of SSL gene familywere originatedfrom gene duplication

other signalsinfluencinggene splicing

these genesmight have resultedfrom gene duplication

genesoriginatesfrom gene duplication

Geneshave originatedby gene duplication

What types of genesresultfrom gene duplication

Paralogous genes ... onesresultfrom gene duplication

the various lipase encoding geneshave ... resultedfrom gene duplication

The paralogous AtPUB46 - 48 genes located in tandem on Arabidopsis chromosome 5resultedfrom gene duplication

a random event ( such as recombinationcausesa gene duplication

The duplications at the target sitecan resultin gene duplication

Another mechanismcausinggene duplication

Gene redundancycan resultfrom gene duplication

sequences ... homologous sequencesresultedfrom gene duplication

to an increase in the number of functional genes coding for one proteinleadto an increase in the number of functional genes coding for one protein

the genome to contain multiple copies of a gene which can then undergo separate evolutionary processescausethe genome to contain multiple copies of a gene which can then undergo separate evolutionary processes

to the expansion and evolution ofhave ... contributedto the expansion and evolution of

to the emergence of novel functionsmay leadto the emergence of novel functions

to the diversification of this gene family with seven members in humansledto the diversification of this gene family with seven members in humans

in function divergenceresultin function divergence

in particularcan resultin particular

to the creation of the copyledto the creation of the copy

in gene clusters in which related or identical genes are arranged in tandemalso have resultedin gene clusters in which related or identical genes are arranged in tandem

A number of genetic diseases of humans(passive) are caused byA number of genetic diseases of humans

to the expansion of the PP2C familycontributedto the expansion of the PP2C family

to functional redundancylikely leadingto functional redundancy

to two identical geneswill leadto two identical genes

to novel peptide ligand / receptor interactionscan leadto novel peptide ligand / receptor interactions

in loss of functionresultin loss of function

to heterodimeric RCsledto heterodimeric RCs

in separate Lim1 and Lim5 clades in the vertebratesresultingin separate Lim1 and Lim5 clades in the vertebrates

to additional genetic ' informationleadingto additional genetic ' information

loss of nerve conductioncausesloss of nerve conduction

hereditary mixed polyposis syndrome(passive) caused byhereditary mixed polyposis syndrome

in the production of two copies of the same protein ... only one of which is necessary for its given functionresultsin the production of two copies of the same protein ... only one of which is necessary for its given function

in gene families , which are groups of related genes within an organisms genomehas resultedin gene families , which are groups of related genes within an organisms genome

to the formation of a gene with a different functioncan leadto the formation of a gene with a different function

functional diversity and further altered expression profiles and protein propertiesmay causefunctional diversity and further altered expression profiles and protein properties

the evolution of gene networks is one of the core problems in evolutionhas influencedthe evolution of gene networks is one of the core problems in evolution

to individuals with two copies of a gene where in their ancestors there was only oneoccasionally leadsto individuals with two copies of a gene where in their ancestors there was only one

to new gene copy which should have a mutationleadsto new gene copy which should have a mutation

in functional diversification Gene duplicationresultingin functional diversification Gene duplication

in functional diversification Gene duplicationresultingin functional diversification Gene duplication

in two or more copies of a generesultsin two or more copies of a gene

to an increased gene numberleadingto an increased gene number

copy number variants , which result in chromosomes with multiple copies of genescan causecopy number variants , which result in chromosomes with multiple copies of genes

in a large expansion of this protein familyhas resultedin a large expansion of this protein family

to new functional genesmight leadto new functional genes

in altered functional constraints between members of a gene familymay resultin altered functional constraints between members of a gene family

in genes with new functionscould resultin genes with new functions

in a nonfunctional copy of a gene , or a functional copy may be subject to mutations that result in loss of functionmay resultin a nonfunctional copy of a gene , or a functional copy may be subject to mutations that result in loss of function

to the formation of a genecan leadto the formation of a gene

an elevated level of its protein productcausesan elevated level of its protein product

to rapid evolution of new or more efficient functionscan leadto rapid evolution of new or more efficient functions

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