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quantitative changesresultingfrom a process of gene amplification
activity in cells ... resistance to imatinib ... andresultedfrom BCR - ABL gene amplification
activity in cells ... resistance to imatinibresultedfrom BCR - ABL gene amplification
mainly(passive) is ... composedThe gene amplification instrument
follicle cellsleadsto extensive gene amplification
p53 mutations ... the p63 genecausesamplification of the EGFR gene
mutationscausingnative gene amplification
AR overexpression ,may resultfrom AR gene amplification
Methotrexatecausesamplification of the dihydrofolate reductase gene
d DNA breaks in p53-deficient cellsleadto oncogenic gene amplification
Unrepaired DNA breaks in p53-deficient cellsleadto oncogenic gene amplification
Site - specific DNA replication at the chorion loci in Drosophila follicle cellsleadsto extensive gene amplification
first(passive) was ... discoveredAmplification of the HER2 gene
in a few resistant(passive) was discoveredMDR1 gene amplification
the addition of methotrexatecausesgene amplification of the DHFR gene
The different chromosomal mechanismsleadingto gene amplification
However the box office performance of Katzman 's action movies and serials , particularly Superman was outstripping those for Gene Kupra's musicals and comediesleadingGene Kupraaway
expression , or sequencescauseamplification of the gene
repetitive genetic sequencesresultsin gene amplification
one or both copies of wild type p53 alleles ... sufficientto causegene amplification
its abnormalities such as overexpression as well asmay contributegene amplification
genesinfluencinggene - amplification
sequencescauseamplification of the gene
the primary mechanismscausinggene amplification
DNA breakageleadsto gene amplification
according to the nucleotide sequence deposited in GenBank(passive) were designedgene amplification
Genetic duplicationsresultingfrom gene amplification
expressioncan resultfrom gene amplification
the cell ... sufficientto causegene amplification
common chromosomal fragile sites , defects in DNA replication , or telomere dysfunction(passive) may be influenced byGene amplification
which levelsresultfrom gene amplification
the Vpr - induced chromosome breaksleadingto gene amplification
extra copiesresultingfrom gene amplification
Rresultingfrom gene amplification
Primers(passive) were designedAmplification of the genes
Stepwise increasing of inhibitor concentrationleadsto gene amplification
fragile sitescausinggene amplification
a possibilityto influencegene amplification
a recurrent rearrangement ,resultingin gene amplification
DNA re - replicationleadingto gene amplification
to an increase in transcription and protein product for that genecan leadto an increase in transcription and protein product for that gene
in increased EGFR activitycan resultin increased EGFR activity
to extra chromosomal copies of a proto - oncogeneleadingto extra chromosomal copies of a proto - oncogene
to disease progression in breast cancercontributesto disease progression in breast cancer
from recombination eventsto resultfrom recombination events
to uncontrolled cell proliferationcontributeto uncontrolled cell proliferation
to AR protein overexpressionleadingto AR protein overexpression
in over - expression of Met proteinresultsin over - expression of Met protein
to overexpressionleadingto overexpression
to increased activity of the EGFR pathwayleadsto increased activity of the EGFR pathway
in over - expression of Her2 proteinresultsin over - expression of Her2 protein
in its overexpressionresultsin its overexpression
in overexpression of Her2 proteinresultsin overexpression of Her2 protein
c - MET activation(passive) can be caused byc - MET activation
MET activation(passive) can be caused byMET activation
methyltransferase SETDB1contributesmethyltransferase SETDB1
to overproduction of the HER2 proteincan leadto overproduction of the HER2 protein
a type of breast cancer(passive) caused bya type of breast cancer
protein overexpression(passive) is caused byprotein overexpression
to distant metastasiscontributingto distant metastasis
to over - expression of its protein productinvariably leadsto over - expression of its protein product
to a total copy number of 60leadingto a total copy number of 60
HER-2 overexpression(passive) is caused byHER-2 overexpression
overexpressioncausesoverexpression
from a copy number increase associated with overexpression of the amplified generesultsfrom a copy number increase associated with overexpression of the amplified gene
to high levels of protein ( receptor ) expressionleadsto high levels of protein ( receptor ) expression
in the early 1980swas discoveredin the early 1980s
to AR protein overexpression ... and subsequently to increased AR signalingmay leadto AR protein overexpression ... and subsequently to increased AR signaling
to increased expression of the encoded protein in cellsusually leadsto increased expression of the encoded protein in cells
resistance to ARTmay causeresistance to ART
in gene overexpressionresultsin gene overexpression
to the overexpression of the geneleadingto the overexpression of the gene
receptor overexpression and activation of downstream pathwayscausingreceptor overexpression and activation of downstream pathways
overexpression of proteinmay causeoverexpression of protein
protein overexpression(passive) is ... caused byprotein overexpression
in up to 20 copies of the same generesultingin up to 20 copies of the same gene
to production of increased numbers of a gene copiesmay leadto production of increased numbers of a gene copies
to extreme amounts of the gene productleadingto extreme amounts of the gene product
to the growth of cancermay also leadto the growth of cancer
in the growth of cancermay also resultin the growth of cancer