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Qaagi - Book of Why

Causes

Effects

GABAB receptorscausinginhibition of the release of GABA

Glutamate spilloverleadsto inhibition of GABA release

Benzodiazepinescauseenhanced GABA inhibition

calcium and potassium influxcausesneuronal inhibition

the synapsecausingneuronal inhibition

TMScausesneuronal inhibition

a reduction in the probability of action potential initiationcausingneuronal inhibition

A reduction in the probability of action potential generationcausesneuronal inhibition

Activation of GIRK by mGluRsshould causeneuronal inhibition

activation of the CB1 receptor by cannabinoidscausesan inhibition of GABA

CB1 Receptor activationwill leadto GABA inhibition

Stresscausescortical inhibition

by the extract of Drymis winteri (passive) caused byoedema inhibition

by the extract of Drymis Winteri(passive) caused byoedema inhibition

relatedto promptVEGF inhibition

retrograde signal from metabotropic glutamate to cannabinoid receptors(passive) caused byPresynaptic inhibition

Activation of GABAB receptorscausespresynaptic inhibition

a - aminobutyric acidcan resultGABA). This inhibition

the CLAVATA1 receptorultimately causingWUSCHEL inhibition

by pro - inflammatory cytokine cascades(passive) caused byAcetylcholine inhibition

pro - inflammatory cytokine cascades(passive) caused byAcetylcholine inhibition

that has previously been shownto causepresynaptic inhibition

Crcausedinhibition of U46619

This primary afferent depolarizationcausespresynaptic inhibition

compoundscausingPCSK9 inhibition

endogenous adenosine(passive) caused bypresynaptic inhibition

sorafenibcausingsynergistic inhibition

the concentrationscausingreuptake inhibition

Histoneleadsdeacetylase inhibition

a sudden shock ... orcausingvagal inhibition

by the tramadol(passive) caused byreuptake inhibition

High dosescan causeCox-1 inhibition

> High dosescan causeCox-1 inhibition

By selectively exciting A - beta nerve fibres in the skin with TENS , the amount of painful stimulation being transmitted by smaller diameter A - delta and C - fibres can be reducedcausingsegmental inhibition

the mechanism of the P450-catalyzed conversion of NMH ... a nitrosomethane intermediatecausesP450 inhibition

Robert D. McIntosh , Antimo Buonocorecan causeSaccadic inhibition

lot of things that physical therapists , physicians , strength and conditioning experts , and coaches docauseneuromuscular inhibition

The aim of achieving a satisfactory statement given of source of stored serotonin amfetamine , cocaine , fenu- ramine , mdma , meperidineleadsreuptake inhibition

in our studydiscoveredin our study

in synaptic GABA accumulationresultsin synaptic GABA accumulation

in increased concentrations of GABA in the CNS thereby enhancing inhibitory neurotransmissionwill resultin increased concentrations of GABA in the CNS thereby enhancing inhibitory neurotransmission

an increase in dopaminecausesan increase in dopamine

to apoptosisleadsto apoptosis

to accumulation of DNA damage and tumor cell deathleadsto accumulation of DNA damage and tumor cell death

shunting of pEPSPcausingshunting of pEPSP

to tumor cell death in patients with altered DNA repair genescan leadto tumor cell death in patients with altered DNA repair genes

in weakness of the muscleresultsin weakness of the muscle

The pain(passive) can be caused byThe pain

The pain(passive) might be caused byThe pain

the accumulation of lethal DNA damage specifically in tumor cellscausesthe accumulation of lethal DNA damage specifically in tumor cells

to accumulation of DSBsleadsto accumulation of DSBs

to antibiotic accumulation in the cellsleadingto antibiotic accumulation in the cells

alsomay ... contributealso

in weakness of the muscle Once swellingresultsin weakness of the muscle Once swelling

to disease suppression ( 10might leadto disease suppression ( 10

to an over - activation of the NHEJ repair pathwayleadsto an over - activation of the NHEJ repair pathway

in cell cycle arrestresultedin cell cycle arrest

through induction of caspase 8causesthrough induction of caspase 8

to double - strand breaksleadsto double - strand breaks

to transformation of single - strand breaksleadsto transformation of single - strand breaks

G2 delaycausesG2 delay

alsoresultsalso

in synthetic lethalitywould resultin synthetic lethality

cell deathdid ... influencecell death

The discomfort(passive) can be caused byThe discomfort

a decrease in Alt - EJ that is enhanced by Ku70 losscausesa decrease in Alt - EJ that is enhanced by Ku70 loss

the phosphorylation status of serine 5would influencethe phosphorylation status of serine 5

a reduction in Alt - EJ that is enhanced by Ku70 losscausesa reduction in Alt - EJ that is enhanced by Ku70 loss

in a reduction in macrophage accumulation and Ccl2resultedin a reduction in macrophage accumulation and Ccl2

to the accumulation ofshould leadto the accumulation of

to radiosensitizationleadsto radiosensitization

to the persistence of endogenous SSBs that are converted to DSBs during DNA replicationleadsto the persistence of endogenous SSBs that are converted to DSBs during DNA replication

to the persistence of endogenous SSBs which are converted to DSBs during DNA replicationleadsto the persistence of endogenous SSBs which are converted to DSBs during DNA replication

to the induction of FAK signaling inleadsto the induction of FAK signaling in

to re injury in hamstring strainscan leadto re injury in hamstring strains

to replication fork collapseleadsto replication fork collapse

alsoresultedalso

a partial or acute loss of kinase activity(passive) caused bya partial or acute loss of kinase activity

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