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Qaagi - Book of Why

Causes

Effects

characteristic chromosomal translocationsresultingin chimeric fusion proteins

chromosomal translocations as targets for cancer vaccines(passive) created byfusion proteins

chromosomal translocations ( EWS - FLI1 , EWS - ERG etc(passive) created byfusion proteins

chromosomal translocations that play a role in oncogenesis of these tumors ( 3 – 5(passive) created bythe fusion proteins

chromosomal translocations , such as BCR - ABL in chronic myelocytic leukemia ( 24(passive) created byfusion proteins

the large chromosomal translocations t(8;21 ) , t(15;17 ) , and t(9;11 ) ,createthe fusion proteins

» Amatruda Lab » Research » Ewing Sarcoma Ewing Sarcoma ... chromosomal translocationscreateoncogenic fusion proteins

chromosomal translocations to stimulate transcriptional elongation of HIV-1 and MLL - target genes , respectively(passive) created byfusion proteins

chromosomal translocations affecting the MLL gene at the 11q23 chromosome locus.22 Aberrant fusion proteins involving the MLL histone methyltransferase ( HMT(passive) created byMLL fusion proteins

Chromosomal rearrangements ... intragenic , reciprocal translocationsresultin fusion proteins

GST is commonly used as a tagto createfusion proteins

combining two different genes ( or recipes ) to produce one final product(passive) are created byFusion proteins

orderto createLacZ - dockerin fusion proteins

the peptide SIGYPLP and the positive control peptide KKKKKKK upstream of the S11e single - chain Fv ( “ adenobody ” ) directed against the knob domain of the adenovirusto createfusion proteins

inserting the full - length Cul3 sequence into pECFP - C1 or pEYFP - C1 plasmids ( Clontech , Mountain View , CA(passive) were created byCul3 fusion proteins

fusing a soluble TWEAKR to an Fc polypeptide(passive) created bytwo fusion proteins

two genes — originally coding for separate proteins — joining together(passive) are created byFusion proteins

with a cytokine N - terminal domain and the encephalitogenic peptide 69 - 88 of guinea pig myelin basic protein ( GP69 - 88 ) as the C - terminal domain(passive) were designedFusion proteins

containing aEF1 alpha promoter and the myc leader peptideto createfusion proteins

e.g. , translocationsresultingin TRK fusion proteins

to lack thenatural glycine – glycine motif that forms the isopeptidebond with the target lysine side chain , and thus cannotbe cleaved by SUMO peptidases(passive) were designedThe fusion proteins

The ORF of AtPAP1 ( GenBank Accession Number NM_104541.3 ... then fused to the GAL4 activation domain in vector pGADT7-Rec2 ( Clontechto createthe fusion proteins

For example , the expression vector pUR278 ( Ruther et al . , EMBO J. , 2:1791 , 1983 ) can be usedto createlacZ fusion proteins

the Philadelphia chromosomal translocation(passive) caused bya fusion proteins

MLL rearrangements(passive) caused bythe fusion proteins

hadler@u.washington.eduAbstractOne of the most common chromosomal abnormalities in acute leukemia is a reciprocal translocation involving the HRX gene at chromosome locus 11q23resultingin HRX fusion proteins

joined genes(passive) are created byFusion proteins

these rearranged genes(passive) created byThe fusion proteins

chromosomal translocation such as Bcr - Abl(passive) created byfusion proteins

to self - assemble on the cellulose surface , leading into the submonolayer of proteins having the HFBI pointing away from the surface(passive) are designedThe fusion proteins

BioBricks ... being usedto createfusion proteins

Two fragments of the su1 cDNA are usedto createfusion proteins

acidic conditions ... raising the temperature at neutral(passive) are triggered byfusion proteins

through the genetic engineering of two or more genes that originated from separate proteins and impart properties from each of the parent proteins(passive) are createdFusion proteins

The pET28a plasmid was usedto createfusion proteins CBM3a

The pCMV - GH vector ( Laboratory of Dr. Stephen A. Johnston , Department of Biochemistry , The University of Texas , Dallas , Tex . ) containing the human growth hormoneto createfusion proteins

The majority of CML patients ( 95 % ) display M - BCR breakpointsresultingin p210 fusion proteins

merging the ORF of two proteins and removing the stop codon between them(passive) can be created byFusion proteins

the cyan fluorescent protein ... can be usedto createfusion proteins

Recombinant technology is widely usedto createfusion proteins

from chromosomal translocations in cancerresultingfrom chromosomal translocations in cancer

from aberrant chromosomal translocationsresultingfrom aberrant chromosomal translocations

from oncogenic chromosomal translocationsresultingfrom oncogenic chromosomal translocations

from internal deletions or chromosomal translocationsresultingfrom internal deletions or chromosomal translocations

from chromosomal translocations such as BCR - ABLresultingfrom chromosomal translocations such as BCR - ABL

from chromosomal translocations in pediatric AMLsresultingfrom chromosomal translocations in pediatric AMLs

from these variant translocationsresultingfrom these variant translocations

from oncogenic translocationsresultingfrom oncogenic translocations

from chromosomal translocations ( e.g. , Bcr - Ablresultingfrom chromosomal translocations ( e.g. , Bcr - Abl

from chromosomal translocations associated with acute myeloid leukemia [ 3resultingfrom chromosomal translocations associated with acute myeloid leukemia [ 3

from chromosomal translocations associated with acute myeloid leukemia [ 19resultingfrom chromosomal translocations associated with acute myeloid leukemia [ 19

an axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas ' , Journal of Pathologytriggeran axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas ' , Journal of Pathology

from leukemia - related translocationsresultingfrom leukemia - related translocations

upon translocations at the human MOZ locuscreatedupon translocations at the human MOZ locus

in the present studydesignedin the present study

of N copies of the linked polypeptidescomposedof N copies of the linked polypeptides

from translocations , or products of normal but silent genes ( 1resultingfrom translocations , or products of normal but silent genes ( 1

of the GAD and mutagenized Sml1composedof the GAD and mutagenized Sml1

of codons 234 to 365 of human MEF2Bcomposedof codons 234 to 365 of human MEF2B

in the cytosoloriginatingin the cytosol

from translocations , such as the DNAJB1-PRKACA chimaeric transcript in fibrolamellar HCC.95resultingfrom translocations , such as the DNAJB1-PRKACA chimaeric transcript in fibrolamellar HCC.95

of the GAL4 DNA - binding domain and random segments of E. 88composedof the GAL4 DNA - binding domain and random segments of E. 88

from the chromosomal rearrangement of RETresultingfrom the chromosomal rearrangement of RET

of the terminal 48 or 50 amino acids of mature betacellulin and a binding defective form of Pseudomonas exotoxin ( BTC - TX48 and BTC - TX50 , respectivelycomposedof the terminal 48 or 50 amino acids of mature betacellulin and a binding defective form of Pseudomonas exotoxin ( BTC - TX48 and BTC - TX50 , respectively

of glutathione transferase ( GSTcomposedof glutathione transferase ( GST

in free cytosolic eYFPresultingin free cytosolic eYFP

of segments of nuclear - encoded organelle polypeptides and an enzymatic reportercomposedof segments of nuclear - encoded organelle polypeptides and an enzymatic reporter

of ELPs and Caveolin 1composedof ELPs and Caveolin 1

of Fc regions of IgG1 fused with another moleculecomposedof Fc regions of IgG1 fused with another molecule

of the human being placental isozyme of alkaline phosphatase ( AP ) in the N - terminus and murinecomposedof the human being placental isozyme of alkaline phosphatase ( AP ) in the N - terminus and murine

of two or more fused proteins – proteins that originally functioned independentlyare composedof two or more fused proteins – proteins that originally functioned independently

of three functional parts : secretion signal peptide ( Usp45composedof three functional parts : secretion signal peptide ( Usp45

of a PRLR antagonist ( G129R ) and anti - tumor domains were developedcomposedof a PRLR antagonist ( G129R ) and anti - tumor domains were developed

to sustained T cell activation , and long - term survival of mice with established tumorsleadsto sustained T cell activation , and long - term survival of mice with established tumors

of the A(1)-adenosine receptor and G protein alpha - subunitscomposedof the A(1)-adenosine receptor and G protein alpha - subunits

an axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas — Italian Ministry of Health Monica Brenca , Silvia Stacchiotti , Kelly Fassetta , Marta Sbaraglia , Milijana Janjusevic , Dominga Racanelli , Maurizio Polano , Sabrina Rossi , Silvia Brich , Gian Paolo Dagrada , Paola Collini , Chiara Colombo , Alessandro Gronchi , Annalisa Astolfi , Valentina Indio , Maria Abbondanza Pantaleo , Piero Picci , Paolo G Casali , Angelo Paolo Dei Tos , Silvana Pilotti & 1 otherstriggeran axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas — Italian Ministry of Health Monica Brenca , Silvia Stacchiotti , Kelly Fassetta , Marta Sbaraglia , Milijana Janjusevic , Dominga Racanelli , Maurizio Polano , Sabrina Rossi , Silvia Brich , Gian Paolo Dagrada , Paola Collini , Chiara Colombo , Alessandro Gronchi , Annalisa Astolfi , Valentina Indio , Maria Abbondanza Pantaleo , Piero Picci , Paolo G Casali , Angelo Paolo Dei Tos , Silvana Pilotti & 1 others

of the NH2-terminal and hydrophobic domain of ten - m1 attached to the alkaline phosphatase reporter genecomposedof the NH2-terminal and hydrophobic domain of ten - m1 attached to the alkaline phosphatase reporter gene

of lactaptin and peptides specific for human tumorscomposedof lactaptin and peptides specific for human tumors

of the A1-Adenosine Receptor and G Protein { alpha}-SubunitsAbstractFulltextPDFWeb of ScienceComposedof the A1-Adenosine Receptor and G Protein { alpha}-SubunitsAbstractFulltextPDFWeb of Science

of canine gnrh and t helper ( th ) cell epitope p35composedof canine gnrh and t helper ( th ) cell epitope p35

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