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Smart Reasoning:

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Qaagi - Book of Why

Causes

Effects

Deletion or insertion of three or a multiple of three base pairs within coding sequencesdoes ... causeframeshift mutation

Deletion of just one nucleotide in a protein - coding part of a genewill causea " frameshift mutation

insertion or deletion mutations , nonsense mutations , and splice - site mutations(passive) caused byframeshift mutations

Deletion or insertion of three or a multiple of three base pairs inside coding sequencesdoes ... causeframeshift mutation

from and insertion or deletion of nucleotide pairs in a gene(passive) is causeda frameshift mutation

the insertion or deletion of a single nucleotide ( DNA basecauseda frameshift mutation

Insertion , deletion and duplication mutationscauseFRAMESHIFT MUTATIONS

when there are insertions , deletions and duplication of the DNA bases in a gene(passive) are also causedFrameshift mutations

by any insertion or deletion of a base pair(passive) caused byFrameshift mutations

the NHEJ pathway that results in the insertion or deletion of a random base at the site of repaircausesa frameshift mutation

by the deletion or insertion of a single base(passive) caused bya frameshift mutation

The insertion or deletion of a single basecausesa frameshift mutation

Insertions and deletion of single nucleotidescan causeframeshift mutations

a base pair ... an insertion or a deletioncausesa frameshift mutation

by nucleotide insertion or deletion(passive) caused byframeshift mutations

Mutations ) insertion Results in the addition of extra DNA Insertionscan causeframeshift mutations

that cause insertion or deletion of base pairsresultingin frameshift mutation

Insertion and deletion mutationscan potentially causeframeshift mutation

by a single adenine deletion in exon 5 that results in a premature stop codon(passive) caused bya frameshift mutation

a novel deleterious homozygous four - nucleotide deletioncausingframeshift mutation

by small deletion or insertion(passive) caused byframeshift mutations

by exon 9 deletions or insertions(passive) caused byframeshift mutations

by a deletion of a base , or an insertion of a base(passive) can be causedA frameshift mutation

deletion or insertion and aberrant splicing(passive) caused byframeshift mutations

insertions or deletions of base pairscauseframeshift mutations

by one base deletion(passive) caused bya frameshift mutation

by base pair deletions(passive) caused byframeshift mutations

a single - base deletion(passive) caused bya frameshift mutation

an insertion or deletion of a nucleotide causing the reading frame to shift & the protein(passive) are caused byFrameshift mutations

by deletion or addition of nucleotide / s leading to change in the reading of the sequence(passive) are caused byFrameshift mutations

by deletion or addition of nucleotide(passive) are caused byFrameshift mutations

insertions or deletions of nucleotides(passive) are caused byFrameshift mutations

by a single base insertion on chromosome 10(passive) caused bya frameshift mutation

DELETION ... NONsense mutationresultsin FRAMESHIFT mutation

Single nucleotide INSERTION / DELETIONcausesFRAMESHIFT mutation

the insertion or deletion of a single nucleotidecauseda frameshift mutation

the insertion or deletion of a single nucleotidecauseda frameshift mutation Frameshift mutation

the addition or deletion of nucleotides(passive) are caused byFrameshift mutations

either by the addition of a nucleotide or by a deletion(passive) are causedFrameshift mutations

the deletion of one or more nucleotides(passive) can be caused byThe frameshift mutation

prematurecausingpremature

premature stop codon and production of truncated proteincausespremature stop codon and production of truncated protein

a premature stop codon and protein truncation ( 29causinga premature stop codon and protein truncation ( 29

in a truncated form of the protein encoded by the essential generesultingin a truncated form of the protein encoded by the essential gene

the leucine ( Leu ) at amino acid position 192 to become a termination codon , leading to termination of protein sequence codingcausesthe leucine ( Leu ) at amino acid position 192 to become a termination codon , leading to termination of protein sequence coding

in a premature stop codon that in turn leads to the production of a shorter proteincan resultin a premature stop codon that in turn leads to the production of a shorter protein

to premature chain termination and the expression of a receptor lacking the kinase domainleadingto premature chain termination and the expression of a receptor lacking the kinase domain

to premature termination of the protein transcriptleadsto premature termination of the protein transcript

in a premature truncation of the proteinresultin a premature truncation of the protein

to a premature stop codon after a sequence of aberrant amino acidsleadingto a premature stop codon after a sequence of aberrant amino acids

to premature truncation of protein by a stop codon ( arrowleadsto premature truncation of protein by a stop codon ( arrow

to premature truncation of proteinleadsto premature truncation of protein

a premature stop codon in the glycophorin C genecausinga premature stop codon in the glycophorin C gene

to premature stop codons , which prevent the formation of LIFR proteinleadingto premature stop codons , which prevent the formation of LIFR protein

to loss of function of the protein in developmental disorder sotos syndromeleadsto loss of function of the protein in developmental disorder sotos syndrome

in reduced activity of the protein encoded by the genemay resultin reduced activity of the protein encoded by the gene

to formation of a truncated gene productleadingto formation of a truncated gene product

in a premature stop codon in exon 4resultingin a premature stop codon in exon 4

a shift in reading frame leading to a complete change of the amino acid sequence downstream of the mutation ( i.e. , the frameshift sitecausea shift in reading frame leading to a complete change of the amino acid sequence downstream of the mutation ( i.e. , the frameshift site

in premature termination of the generesultingin premature termination of the gene

an in - exon stop codon 6 amino acids downstream of the end of the deletioncausingan in - exon stop codon 6 amino acids downstream of the end of the deletion

to a premature stop codon and premature chain terminationledto a premature stop codon and premature chain termination

to truncation of the resulting proteinleadingto truncation of the resulting protein

to premature termination of translationleadingto premature termination of translation

to premature stop codons , null mutations , and missense mutationsleadingto premature stop codons , null mutations , and missense mutations

premature stop codons , null mutations , and missense mutationsleadingpremature stop codons , null mutations , and missense mutations

in a premature stop codon in exonresultedin a premature stop codon in exon

in a truncated proteinresultingin a truncated protein

in a premature stop codon in exon 10resultingin a premature stop codon in exon 10

to truncated protein productsleadingto truncated protein products

to truncated protein productsleadto truncated protein products

in a premature stop codon and a missense mutation inresultingin a premature stop codon and a missense mutation in

to truncated proteins with impaired or no functionleadingto truncated proteins with impaired or no function

to truncated proteins with impaired functionleadingto truncated proteins with impaired function

to premature STOP codonsleadingto premature STOP codons

premature stop codonscausingpremature stop codons

in premature stop codonsresultin premature stop codons

to premature stop codonsleadto premature stop codons

premature stop codonsleadpremature stop codons

in premature stop codonsresultingin premature stop codons

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