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Due to interaction of copanlisib with warfarin , patients who are on warfarin should be monitored closely while on this trial Patients and their partners , if sexually active and of childbearing potential , must agree to the use of two highly effective forms of contraception in combination throughout the period of taking study treatment and for 7 months after last dose of study drug(s )to preventpregnancy in
Patients should not become pregnant or breastfeed while on this study - Patients and their partners , if sexually active and of childbearing potential , must agree to the use of two highly effective forms of contraception in combination throughout the period of taking study treatment and for 7 months after last dose of study drug(s )to preventpregnancy in
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