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Qaagi - Book of Why

Causes

Effects

by mutations in the(passive) caused byMOPD1 deficiency

heterozygous or homozygous mutation in the OPLAH gene ( 5-Oxoprolinase(passive) can be caused by5-oxoprolinase deficiency

Underactive pituitary glandmay causeACTH deficiency

mutationcausedheme deficiency

recessive mutations in the AAT gene(passive) is caused byAntitrypsin deficiency

The alas1 mutationcausedheme deficiency

the homozygous p(passive) caused byTransaldolase deficiency

by a novel mutation(passive) caused byantitrypsin deficiency

several types of porphyria(passive) caused byHeme deficiency

by a novel mutation ( p(passive) caused byantitrypsin deficiency

compound heterozygosity for two novel mutations in the TCN2 gene(passive) caused byTranscobalamin deficiency

mutations in the HSD17B4 gene(passive) is caused byDBP deficiency

More than 20 mutations in the TCN2 gene have been foundto causetranscobalamin deficiency

at any age(passive) can be discoveredFibrinogen deficiency

either inadequate intake , inadequate absorption from food or malabsorption due to intestinal problems(passive) is caused byDeficiency

inadequate supply to the body , improper absorption by the body of such nutrients or due to unable to maintain the content of zinc vitamins required by the body(passive) may be caused byDeficiency

homozygous or compound heterozygous mutations in DOCK8 gene(passive) is caused byDOCK8 deficiency

Dna2resultsnuclease deficiency

the factor that sometimes it is not absorbed properly , ... : It is generally not the lack of B12 in our diet that leads to a functional decrease in B12 levelscausesdeficiency

lack of B12 in the diet , pernicious anemia or impaired absorption by the intestines(passive) can be caused byDeficiency

by celiac disease(passive) caused byCholecystokinin deficiency

inadequate exposure to sunlight and low consumption of foods containing Vitamin D.(passive) is caused byDeficiency

complete deficiency of the protein DOCK8(passive) is caused byDOCK8 deficiency

inadequate dietary intake of the vitamin , malabsorption , metabolic abnormalities , or drug - nutrient interactions(passive) is caused byDeficiency

lack of exposure to sunlight , dietary deficiency or malabsorption(passive) is caused by Deficiency

low dietary intake , malabsorption and increased excretion due to common illnesses(passive) is caused byDeficiency

disease , drug use , reduced digestive function , or inadequate magnesium intake(passive) may be caused byDeficiency

not by a lack of B-12 in the diet , but rather impaired absorption(passive) is often causedDeficiency

by disease and syndrome of spleen deficiency syndrome(passive) caused bydeficiency

For the body to absorb vitamin b12 better there is a requirement of a protein called intrinsic factor , lack of this proteintoo can causedeficiency

a lack of intrinsic factor - the substance needed for the absorption of vitamin B12(passive) is also caused byDeficiency

a prolonged vegan diet without supplementation , alcoholism(passive) can be caused byDeficiency

inadequate dietary intake of the vitamin , malabsorption , or metabolic abnormalities(passive) is caused byDeficiency

by two novel mutations in factor(passive) caused by deficiency

by two novel mutations in factor (passive) caused by deficiency

poor diet or genetic factors ( such as mutations in the BTD gene(passive) can be caused byDeficiency

low soil and dietary levels(passive) caused byDeficiency

by poor absorption Deficiency(passive) usually caused bydeficiency

malabsorption disorders and prolonged antibiotic treatment , chronic diarrhea and some liver disorderscan causedeficiency

mutations in the SERPINA1 gene , located on chromosome 14(passive) is caused byDeficiency

to exercise intolerance and cardiac dysfunctionleadsto exercise intolerance and cardiac dysfunction

in increased proliferation of the bladder urotheliumresultedin increased proliferation of the bladder urothelium

developmental defects in the substantia nigra(passive) caused bydevelopmental defects in the substantia nigra

to impairment of many cellular functionsleadsto impairment of many cellular functions

bone overgrowth ( osteopetrosiscausesbone overgrowth ( osteopetrosis

some of the phenotypic features of aneuploid cells(passive) might be caused bysome of the phenotypic features of aneuploid cells

a number of symptoms including irregular heartbeat , anemia , nerve damage , mental confusion , impaired memory , depression , headaches , and irritabilitycausesa number of symptoms including irregular heartbeat , anemia , nerve damage , mental confusion , impaired memory , depression , headaches , and irritability

to soft brittle nails , ageing symptoms of skin such as wrinkles , thinning or loss of hair , poor bone development , insomnia , osteoporosiscan leadto soft brittle nails , ageing symptoms of skin such as wrinkles , thinning or loss of hair , poor bone development , insomnia , osteoporosis

to soft brittle nails , ageing symptoms of skin such as wrinkles , thinning or loss of hair , poor bone development , insomnia and osteoporosiscan leadto soft brittle nails , ageing symptoms of skin such as wrinkles , thinning or loss of hair , poor bone development , insomnia and osteoporosis

to a signaling cascade that ultimately disturbed the balance between ARE and non - ARE myelin mRNAs ... culminating in demyelinating diseaseleadsto a signaling cascade that ultimately disturbed the balance between ARE and non - ARE myelin mRNAs ... culminating in demyelinating disease

in : acne , alopecia ( loss of body hair ) , anemia , anorexia , nausea , arthritis , cracked lips , conjunctivitis , depression , dizziness , fatigue , slow wound healing , irritability , nervousness , seizuresmay resultin : acne , alopecia ( loss of body hair ) , anemia , anorexia , nausea , arthritis , cracked lips , conjunctivitis , depression , dizziness , fatigue , slow wound healing , irritability , nervousness , seizures

dermatitis , diarrhea , impaired growth , hypogonadism , anemia , enlarged liver , hair loss , and decreased immune functioncausesdermatitis , diarrhea , impaired growth , hypogonadism , anemia , enlarged liver , hair loss , and decreased immune function

severe dermatitis , inflamed and sore tongue , loss of appetite , nausea , depression , anemia , sensitivity of the skin , insomnia and increased blood levels of cholesterolCan causesevere dermatitis , inflamed and sore tongue , loss of appetite , nausea , depression , anemia , sensitivity of the skin , insomnia and increased blood levels of cholesterol

fatigue , glossitis ( tongue inflammation ) , depression , confusion , memory loss , muscle weakness , and numbness and tingling in the hands and feet due to nerve damagecan causefatigue , glossitis ( tongue inflammation ) , depression , confusion , memory loss , muscle weakness , and numbness and tingling in the hands and feet due to nerve damage

in dermatitis , retarded growth , nausea , numbness in the hands and feet , depression , insomnia , irritability , kidney stones , anemia , headaches and otherscan resultin dermatitis , retarded growth , nausea , numbness in the hands and feet , depression , insomnia , irritability , kidney stones , anemia , headaches and others

to pernicious anemia , disorders of the nervous system , headaches , nausea , shortness of breath , weight loss , severe fatigue , dementia , birth defects and a decrease in the formation of white blood cells and plateletscan leadto pernicious anemia , disorders of the nervous system , headaches , nausea , shortness of breath , weight loss , severe fatigue , dementia , birth defects and a decrease in the formation of white blood cells and platelets

anemia , depression , confusion , poor memory and dementiacan also causeanemia , depression , confusion , poor memory and dementia

weakness , irritability , depression , skin disorders , inflammation of the mouth and tongue , anaemia , and , in infants , seizuresmay causeweakness , irritability , depression , skin disorders , inflammation of the mouth and tongue , anaemia , and , in infants , seizures

to hair loss , brittle nails , muscle pain , anaemia and disorders of fat metabolismleadsto hair loss , brittle nails , muscle pain , anaemia and disorders of fat metabolism

to pernicious anemia and symptoms such as pale skin , fatigue , shortness of breath and heart palpitationscan leadto pernicious anemia and symptoms such as pale skin , fatigue , shortness of breath and heart palpitations

Rickets in children , bone softening in adults , insomnia , osteoporosis , tooth decay , muscle weakness , poor calcium absorptionmay causeRickets in children , bone softening in adults , insomnia , osteoporosis , tooth decay , muscle weakness , poor calcium absorption

in anemia , weakness , depression , confusion , memory problems , and fatiguewill resultin anemia , weakness , depression , confusion , memory problems , and fatigue

to anemia , nerve damage , tiredness , weakness , depression , weight loss , and numbness and tingling in the hands and feetcan leadto anemia , nerve damage , tiredness , weakness , depression , weight loss , and numbness and tingling in the hands and feet

infertility , reduction in red blood cell production that leads to anemia , iron metabolism defects and poor bone , tooth and cartilage formationcausesinfertility , reduction in red blood cell production that leads to anemia , iron metabolism defects and poor bone , tooth and cartilage formation

irritability , Depression , loss of concentration ... fatigue and Insomniamay causeirritability , Depression , loss of concentration ... fatigue and Insomnia

not only leg cramps , insomnia and anxiety , but Migraines , fatigue , diabetes , fibromyalgia , high blood pressure , osteoporosis and poor functioning of many essential chemical reactions in the bodycan causenot only leg cramps , insomnia and anxiety , but Migraines , fatigue , diabetes , fibromyalgia , high blood pressure , osteoporosis and poor functioning of many essential chemical reactions in the body

in constipation , anxiety / irritability , fatigue , mental confusion and insomniacan resultin constipation , anxiety / irritability , fatigue , mental confusion and insomnia

in impaired bone mineralization , which can lead to bone softening diseases , rickets in children , and osteomalacia or osteoporosis in adultscan resultin impaired bone mineralization , which can lead to bone softening diseases , rickets in children , and osteomalacia or osteoporosis in adults

in bleeding dysfunction bone disorders such as osteoporosis , rickets , and osteomalaciacan resultin bleeding dysfunction bone disorders such as osteoporosis , rickets , and osteomalacia

fatigue , glossitis ( tongue inflammation ) , depression , confusion , memory loss , muscle weakness , and numbness and tingling in the hands and feetcan causefatigue , glossitis ( tongue inflammation ) , depression , confusion , memory loss , muscle weakness , and numbness and tingling in the hands and feet

in bleeding diabetes bone disorders such as osteoporosis , rickets , and osteomalaciacan resultin bleeding diabetes bone disorders such as osteoporosis , rickets , and osteomalacia

to muscle pains , fatigue , disorders in the nervous system and mental depressionleadsto muscle pains , fatigue , disorders in the nervous system and mental depression

depression , irritability , insomnia , fatigue and anaemiacausesdepression , irritability , insomnia , fatigue and anaemia

in fatigue and symptoms of muscle , gastrointestinal , and cardiac diseasecan resultin fatigue and symptoms of muscle , gastrointestinal , and cardiac disease

weakness , irritability , depression , skin disorders , inflammation of the mouth and tongue , anaemiamay causeweakness , irritability , depression , skin disorders , inflammation of the mouth and tongue , anaemia

weakness , irritability , depression , skin disorders , inflammation of the mouth and tongue , anaemia , andmay causeweakness , irritability , depression , skin disorders , inflammation of the mouth and tongue , anaemia , and

tiredness , weakness , constipation , loss of appetite , weight loss , and megaloblastic anemiamay causetiredness , weakness , constipation , loss of appetite , weight loss , and megaloblastic anemia

dermatitis , depression , confusion and seizures and anemia in adultscan causedermatitis , depression , confusion and seizures and anemia in adults

to depression , anemia , fatigue , and nerve damagecan leadto depression , anemia , fatigue , and nerve damage

fatigue , anxiety , and poor hair and nail conditioncan causefatigue , anxiety , and poor hair and nail condition

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Smart Reasoning:

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