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Qaagi - Book of Why

Causes

Effects

Mutations in the MCFD2 genemay causeFactor V and Factor VIII combined deficiency

Hemophilia A ... a X - linked recessive hereditary clotting factor deficiency conditionleadto decreased factor VIII activity

A ... a X - linked hereditary conditionleadto decreased factor VIII activity

the basisdid ... inventhuman Factor VIII : C

mutations(passive) is caused bydeficiency of Factor V and Factor VIII

The absence of von Willebrand factorcausesfactor VIII to be less stable

mutations in the F7 gene knownto causeFactor VII disorder

a genetic mutation in factor VII production resulting in reduced factor VII activity(passive) is caused by Factor VIII deficiency

a genetic mutation in factor VII production resulting in reduced factor VII activity(passive) is caused byFactor VIII deficiency

variants in the gene that codes for coagulation factor VII(passive) is caused byFactor VII deficiency

by a deficiency or defect in the clotting protein(passive) is ... caused byFactor IX deficiency

Factorsinfluencingfactor VIII activity

a problem with factor VII(passive) is caused byFactor VII deficiency

an X - linked recessive disordercausesfactor VIII deficiency

novel mutation mechanismsleadingto factor VIII deficiency

a change , or mutation(passive) is caused byFactor IX Deficiency

by an inhibitory antibody to factor viii(passive) caused byfactor viii deficiency

an inhibitory antibody to factor VIII(passive) caused byfactor VIII deficiency

This test ... knownto causeFactor VII deficiency

by a promoter mutation(passive) caused byfactor VII deficiency

desmopressincausesrelease of factor VIII

any drugcausingFACTOR VIII DEFICIENCY

other drugscauseFACTOR VIII DEFICIENCY

by the methods(passive) designed byhuman Factor VIII

the basisdid ... inventhuman Factor VIII

a structural variant N57D of the first epidermal growth factor domain(passive) caused byFactor VII deficiency

by a structural variant N57D of the first epidermal growth factor(passive) caused byFactor VII deficiency

other drugscauseFACTOR VIII INHIBITION

mutationscausingfactor VIII assay

by metal - induced oxidation(passive) is causedFactor VIII inactivation

by metal - induced oxidation(passive) is caused byFactor VIII inactivation

a deficiency of factor VIII(passive) is caused byFactor VIII concentrate and cryoprecipitate

of 20 homologous domains(passive) is composedFactor H

a deficiency of clotting factor IX(passive) is caused byFactor IX concentrate

of 20 repetitive modules of approximately about 60 amino acids , the Short Consensus Repeat ( SCR ) which forms a flexible structure(passive) is composedFactor H

factor IX geneleadingto factor VIII

the Factor VIII complexresultsin the Factor VIII

to the average concentration of the measured factors(passive) was setFactor IX

mutationscausingfactor VII

a defective geneleadingto factor VIII

hemophiliacauseshemophilia

an inherited X - linked disease(passive) caused byan inherited X - linked disease

The disorder is mainly an inherited deficiency of the Factor VIII geneCausesThe disorder is mainly an inherited deficiency of the Factor VIII gene

a hematological disorder(passive) caused bya hematological disorder

Factor VIII deficiency ( choice A ) , or hemophilia A(passive) is caused byFactor VIII deficiency ( choice A ) , or hemophilia A

severe hemophiliacausingsevere hemophilia

to severe hemophilia Aleadingto severe hemophilia A

to abnormal bleedingleadingto abnormal bleeding

hemophiliacausinghemophilia

an X - linked recessive disease , usually inherited and affecting primarily males(passive) caused byan X - linked recessive disease , usually inherited and affecting primarily males

hemophilia Acauseshemophilia A

in hemophilia Aresultsin hemophilia A

Combined factor V and(passive) is causedCombined factor V and

Hemophilia A ( classic hemophilia(passive) is caused byHemophilia A ( classic hemophilia

to insufficient fibrin formationleadsto insufficient fibrin formation

haemophilia A(passive) is caused byhaemophilia A

a prolonged aPTTto causea prolonged aPTT

excessive and sometimes fatal bleeding from minor wounds and surgerycausesexcessive and sometimes fatal bleeding from minor wounds and surgery

to deficiency in Factor VIIIleadsto deficiency in Factor VIII

increased clotting and cerebral venous thrombosiscan causeincreased clotting and cerebral venous thrombosis

in greatly enhanced factor VIII activityresultsin greatly enhanced factor VIII activity

in greatly enhanced factor VIII activityresultsin greatly enhanced factor VIII activity

the one - stage prothrombin timeinfluencethe one - stage prothrombin time

a nasty case X - linked Haemophilia B in her male descendants ( a mutation that was only mapped in 2009 by sequencing the bones of the murdered Romanov branchcauseda nasty case X - linked Haemophilia B in her male descendants ( a mutation that was only mapped in 2009 by sequencing the bones of the murdered Romanov branch

A non - genetic form of haemophilia(passive) is caused byA non - genetic form of haemophilia

in decreased levels of coagulation factor VIIIresultingin decreased levels of coagulation factor VIII

What blood disorder(passive) is caused byWhat blood disorder

a rare bleeding disorder(passive) caused bya rare bleeding disorder

increased bleeding and usually affects malescausesincreased bleeding and usually affects males

a bleeding disorder(passive) caused bya bleeding disorder

a severe bleeding disorder(passive) caused bya severe bleeding disorder

in poor responseresultsin poor response

in low factor VIII levels and bleeding patterns similar to those seen in the hemophiliasresultingin low factor VIII levels and bleeding patterns similar to those seen in the hemophilias

thrombin elevation(passive) caused bythrombin elevation

increased bleedingcausesincreased bleeding

from a congenital deficiency or absence of factor IXalso resultsfrom a congenital deficiency or absence of factor IX

in abnormal bleedingresultingin abnormal bleeding

bleeding in patients with factor levels less than 1 percent ( normal is greater than 50 percentcan causebleeding in patients with factor levels less than 1 percent ( normal is greater than 50 percent

hemophilia B.causeshemophilia B.

hemophilia A.causeshemophilia A.

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