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Qaagi - Book of Why

Causes

Effects

too much dopaminemay causea form of schizophrenia Parkinson disease degeneration of dopamine releasing neurons

the brainresultsin dementia Parkinson s disease degeneration of the dopamine - releasing neurons of the substantia

Environmental and genetic risk factorscontributeto Parkinson 's Disease ( PD ) pathogenesis and the associated midbrain dopamine ( mDA ) neuron loss

the pathwayleadingfrom D2 dopamine receptors to the side effects from the treatment of psychoses & Parkinson 's disease

drugsinfluencethe neurotransmitter dopamine that are routinely taken by people with Parkinson s disease

death of these neurons in SNpccausesdopamine deficiency in the striatum ... leading to Parkinson disease ( PD

Loss of dopaminergic neuronsleadsto the loss of the neurotransmitter dopamine and the onset of Parkinson 's symptoms

The observation stating that it is possibleto influencethe symptoms of Parkinson 's disease and psychosis by modifying dopamine activity

exactly whatcausesthe death of dopamine - releasing cells in Parkinson 's disease

low levels(passive) may be caused bySymptoms of Parkinson 's disease ... dopamine in the brain

Nigral iron accumulation and activation of NMDA receptors ( NRscontributeto the neurodegeneration of dopamine ( DA ) neurons in Parkinson 's disease ( PD

Severe movement disordersresultfrom the loss of striatal dopamine in patients with Parkinson 's disease

by genetic mutations in the LRRK2 gene(passive) caused bythe effects of dopamine loss in Parkinson 's disease

Oxidative StressLeadsto Dopamine Neuron Death in Parkinson 's Disease

Nigral iron accumulation and activation of NMDA receptorscontributeto the neurodegeneration of dopamine neurons in Parkinson 's disease

by a deficiency of dopamine(passive) to be caused byThe Dopamine Theory of Parkinson 's Disease ... believed

motor cortexresultingfrom dopamine depletions in animal models of Parkinson disease

While oxidative processes have been reportedto contributeto dopamine neuron loss in Parkinson 's disease

oxidative stresscontributesto the degeneration of dopamine cell in Parkinson 's disease

Toxicity Excessive exposure or intake ... a neurodegenerative disordercausesDopamine neuronal death and symptoms similar to Parkinson 's disease

an imbalance between the oxidation of dopamine and the availability of antioxidant defenses(passive) may be caused bythe selective degeneration of dopamine neurons in Parkinson 's disease

the molecular eventsleadingto the degeneration of dopamine neurons in Parkinson 's disease

The loss of these nerve cellsleadsto decreased dopamine levels resulting in Parkinson 's disease

nausea and vomitingcausedby taking dopamine agonists ( such as bromocriptine and levodopa ) in Parkinson 's disease

manganesecausesParkinson 's Disease by lowering dopamine levels

manganesecan causeParkinson 's Disease by lowering dopamine levels

manganesemay causeParkinson 's disease by lowering dopamine levels

this regionresultsin being hyperactive in Parkinsons sufferers due to loss of dopamine

too muchleadstoo much

Dopa - Responsive Dystonia ... Evidence Observed in Studies on Segawa Disease(passive) Is Caused byDopa - Responsive Dystonia ... Evidence Observed in Studies on Segawa Disease

Dopa - responsive dystonia ... evidence observed in studies on Segawa disease(passive) is caused by Dopa - responsive dystonia ... evidence observed in studies on Segawa disease

symptoms(passive) caused bysymptoms

dyskinesia(passive) caused bydyskinesia

Scientistshave discoveredScientists

the characteristic tremors and coordination problemscausingthe characteristic tremors and coordination problems

to addictive and impulsive disorders that rapidly resolve upon discontinuation of the medicationmay leadto addictive and impulsive disorders that rapidly resolve upon discontinuation of the medication

motor impairment through aberrant motor learningcausemotor impairment through aberrant motor learning

in slow movementsresultingin slow movements

a decrease in the spontaneous activity of the basal ganglionic circuitcausesa decrease in the spontaneous activity of the basal ganglionic circuit

to the muscle rigidity and tremors associated with the disorderleadingto the muscle rigidity and tremors associated with the disorder

to the development of dopamine replacement therapyledto the development of dopamine replacement therapy

movement to become more and more difficultcausingmovement to become more and more difficult

dyskinesia(passive) caused bydyskinesia

tremor , stiffness and movement slowness in patientscausestremor , stiffness and movement slowness in patients

to rigidity stiffness of movement , tremor and other symptoms and signsleadsto rigidity stiffness of movement , tremor and other symptoms and signs

to rigidity stiffness of movementleadsto rigidity stiffness of movement

to rigidityleadsto rigidity

to rigidity , tremor and other signs and signsleadsto rigidity , tremor and other signs and signs

a 200 increase in dopamine release in the brain , with an alteration in the activity of neurons and a corresponding clinical improvement in motor functionto causea 200 increase in dopamine release in the brain , with an alteration in the activity of neurons and a corresponding clinical improvement in motor function

to rigidity , tremor and different signs and signsleadsto rigidity , tremor and different signs and signs

depressioncan ... causedepression

compulsive sexual behaviormay causecompulsive sexual behavior

to Parkinson 's Searchleadsto Parkinson 's Search

compulsive gambling(passive) caused bycompulsive gambling

Nausea and vomiting(passive) caused byNausea and vomiting

Nausea and vomiting(passive) caused byNausea and vomiting

to muscular tremoursleadingto muscular tremours

to changes in learningcontributeto changes in learning

to the symptoms that it doesleadsto the symptoms that it does

in bradykinesia and tremorresultsin bradykinesia and tremor

in shaking and difficulty with walking , movement , speaking , swallowing and coordinationmay resultin shaking and difficulty with walking , movement , speaking , swallowing and coordination

to a breakdown of that balanceleadto a breakdown of that balance

zone 6 necrosis(passive) caused byzone 6 necrosis

a cerebrovascular accident(passive) caused bya cerebrovascular accident

to excessive and abnormally patterned brain cell electrical activity in both the GPi and the STNleadsto excessive and abnormally patterned brain cell electrical activity in both the GPi and the STN

nerves(passive) normally influenced bynerves

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