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Qaagi - Book of Why

Causes

Effects

he foundcausednecrosis of the islet tissue of the pancreas

Glucagoncauseshyperglycaemia within the pancreatic islets

Use of both dietresultedin serious pancreatic islet hyperplasia

Furthermore , at least three additional pathways / interaction networks altered in the adrenal medulla following recurrent hypoglycemia were identified ,may contributeto the impaired epinephrine secretion in HAAF

DPP-4 inhibitors block the degradation of molecules like glucagon - like peptide-1leadingto augmented pancreatic secretion of insulin

A decreased response of the beta cells to gut incretin hormones is thoughtto contributeto the pancreatic endocrine secretory dysfunction

hyperglycemiaresultfrom pancreatic islet dysfunction

Glucagoncauseshyperglycaemia in the pancreatic islets

impaired pancreatic microvascular perfusionleadingto pancreatic ischemia

The factorsleadingto pancreatic ischemia

An acute inflammatory processleadsto necrosis of the pancreatic parenchyma

the cellular eventsleadingto parasympathetic innervation of the endocrine pancreas in zebrafish

This diseasecan also causeExocrine Pancreatic Insufficiency ( EPI

disseminated intravascular coagulation ( DIC ) and cholesterol emboli 5 , 6(passive) caused bypancreatic ischemia

cellsresultingfrom hyperplasia of pancreatic islet

Inflammation of the hypothalamusleadsto defective pancreatic islet

Intraislet endothelial cellscontributeto revascularization of transplanted pancreatic islet

also(passive) was ... influencedEpinephrine - stimulated lipolysis

an enzyme cascadecausesthe hydrolysis of epinephrine

of endocrine cells producing and releasing hormones from secretory granules(passive) is composedThe pancreatic islet of Langerhans

of endocrine cells producing and releasing hormones from secretory granules in response to various stimuli for maintenance of blood(passive) is composedThe pancreatic islet of langerhans

well knownto originatein the pancreatic Islets of Langerhans

of endocrine cells producing and releasing hormones from secretory granules in response to various stimuli for maintenance of blood glucose homeostasis(passive) is composedThe pancreatic islet of Langerhans

Epinephrine ... the adrenal glandresultsin hypersecretion of endogenous epinephrine

Body weight has been foundto influenceepinephrine pharmacokinetics

the researchersdiscoveredthat pancreatic islet

of several cell types(passive) is composedA pancreatic islet

Using animal modelsdiscoveredthat pancreatic islet

of three types of cells of neural crest origin , each with distinct histochemical and electromicroscopic features(passive) is composedThe pancreatic islet

to a diagnosis ofleadsto a diagnosis of

a fall in mean and diastolic pressure with little or no effectcausesa fall in mean and diastolic pressure with little or no effect

a fallcausesa fall

a fall in meancausesa fall in mean

a fall in mean and diastolic pressure with little or no effect on systolic pressurecausesa fall in mean and diastolic pressure with little or no effect on systolic pressure

to hypoglycemia and hyperglycemialeadingto hypoglycemia and hyperglycemia

in severely low blood glucoseresultsin severely low blood glucose

to type 1 diabetesleadingto type 1 diabetes

in severely low bloodresultsin severely low blood

to impaired insulin secretion and type 2 diabetesDoes ... contributeto impaired insulin secretion and type 2 diabetes

to impaired insulin secretionDoes ... contributeto impaired insulin secretion

from the embryonic pancreatic mesenchymeoriginatefrom the embryonic pancreatic mesenchyme

to islet dysfunction in subjects with T2D.contributesto islet dysfunction in subjects with T2D.

tumors to formcausestumors to form

to type 2 diabetesleadto type 2 diabetes

high blood sugar levels in people with Type 2 diabetescauseshigh blood sugar levels in people with Type 2 diabetes

in severely low blood glucose resultsin severely low blood glucose

to the onset of T2DMleadsto the onset of T2DM

problems in how you digest foodcausesproblems in how you digest food

cellsresults cells

to the activation of inflammatory mediatorsleadsto the activation of inflammatory mediators

to impaired insulin secretion and type 2 diabetescontributeto impaired insulin secretion and type 2 diabetes

to cardiovascular actionmight contributeto cardiovascular action

to sensitization of nociceptorscontributesto sensitization of nociceptors

to sensitization of nociceptors after injurycontributesto sensitization of nociceptors after injury

to hepatic glucose productioncontributesto hepatic glucose production

as a primary disease or secondaryresultingas a primary disease or secondary

to loss of insulin secretion and death of insulin - secreting beta cellscontributesto loss of insulin secretion and death of insulin - secreting beta cells

diabetescausediabetes

from endocrine progenitorsoriginatefrom endocrine progenitors

physiological changes in the body , such as constriction of blood vessels , dilation of pupils , increased heart and respiratory rate , and the metabolism of glucosecausesphysiological changes in the body , such as constriction of blood vessels , dilation of pupils , increased heart and respiratory rate , and the metabolism of glucose

immediate reduction in airway inflammationtypically causesimmediate reduction in airway inflammation

vasoconstrictioncausesvasoconstriction

mustberesultmustbe

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