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targeted disruption of the mouse selenocysteine tRNA gene ( Trsp ) , Proc(passive) caused byEarly embryonic lethality
Targeted Disruption of the 3-Hydroxy-3-methylglutaryl - CoA Reductase Gene , The Journal of Biological Chemistry , October 31 , 2003(passive) Caused byEarly Embryonic Lethality
Immunology Disruption of the developmentally regulated Rev3l genecausesembryonic lethality
2000 ) Disruption of the developmentally regulated Rev3l genecausesembryonic lethality
857851711.The absence of the blood clotting regulator thrombomodulincausesembryonic lethality
Pubmed]Absence of the blood - clotting regulator thrombomodulincausesembryonic lethality
Homozygosity for a null allelecausedembryonic lethality
The Dnmt3b null allelecausedembryonic lethality
null alleles of these genescauseembryonic lethality
10.1073 / pnas.1835646100.PubMedPubMed CentralView ArticleGoogle Scholar Ono R , Nakamura K , Inoue K , Naruse M , Usami T , Wakisaka - Saito N , Hino T , Suzuki - Migishima R , Ogonuki N , Miki H , Kohda T , Ogura A , Yokoyama M , Kaneko - Ishino T , Ishino F : Deletion of Peg10 , an imprinted gene acquired from a retrotransposoncausesearly embryonic lethality
a Cabin1 null allele ... likelyto causeembryonic lethality
Targeted Disruption of the Mouse Thioredoxin Gene , 10.1006(passive) Caused byEarly Embryonic Lethality
PubMed ] Wittschieben J. , Shivji M.K. , Lalani E. , Jacobs M.A. , Marini F. , Gearhart P.J. , Rosewell I. , Stamp G. , Wood R.D. Disruption of the developmentally regulated Rev3l genecausesembryonic lethality
Proc Natl Acad Sci USA . 1993 ; 90 : 9355–9358.OpenUrlAbstract / FREE Full Text Healy AM , Rayburn HB , Rosenberg RD , Weiler H. Absence of the blood - clotting regulator thrombomodulincausesembryonic lethality
JAK2 gene knockoutcausesembryonic lethality
Google Scholar ] Wittschieben , J. ; Shivji , M.K. ; Lalani , E. ; Jacobs , M.A. ; Marini , F. ; Gearhart , P.J. ; Rosewell , I. ; Stamp , G. ; Wood , R.D. Disruption of the developmentally regulated Rev3l genecausesembryonic lethality
Homozygous deletion of the PTEN gene in micecausesembryonic lethality
Figure S2).Loss of Nephrocystin-3 FunctionCan CauseEmbryonic Lethality
FoxM1-null mutation in micecausesembryonic lethality
targeted disruption of the mouse thioredoxin gene ' , Developmental Biology(passive) caused byEarly embryonic lethality
33750226235 12/01/1997 Absence of the blood - clotting regulator thrombomodulincausesembryonic lethality
targeted disruption of the 3-hydroxy-3-methylglutaryl - CoA reductase gene Quantitation of the in vitro free cholesterol exchange of human red cells and lipoproteins On the mechanism of transfer of cholesterol between human erythrocytes and plasma Sterol metabolism(passive) caused byEarly embryonic lethality
PMID 11323436 Deletion of Peg10 , an imprinted gene acquired from a retrotransposoncausesearly embryonic lethality
PMID 9094723 Deletion of Peg10 , an imprinted gene acquired from a retrotransposoncausesearly embryonic lethality
Protoc . , 7 ) Deletion of Peg10 , an imprinted gene acquired from a retrotransposoncausesearly embryonic lethality
J:22630 Healy AM , et al . , Absence of the blood - clotting regulator thrombomodulincausesembryonic lethality
disruption of the gene for choline kinase alpha , the first enzyme in phosphatidylcholine biosynthesis C Aoyama(passive) caused byEarly embryonic lethality
the Polr2a R749H mutationcausedembryonic lethality
2006 Ono R , Nakamura K , Inoue K , Naruse M , Usami T , Wakisaka - Saito N , Hino T , Suzuki - Migishima R , Ogonuki N , Miki H , Kohda T , Ogura A , Yokoyama M , Kaneko - Ishino T , Ishino F. Deletion of Peg10 , an imprinted gene acquired from a retrotransposoncausesearly embryonic lethality
complete loss of function of some of these genescausesearly embryonic lethality
Strong allelescauseembryonic lethality
Both deletion allelescauseembryonic lethality
none of these allelescausesembryonic lethality
1995 Jul;74(1):52 - 7.The absence of the blood clotting regulator thrombomodulincausesembryonic lethality
Loss of function mutations of lanA gene in D. melanogastercausedembryonic lethality
Complete loss - of - function mutations of murine GARP componentscauseembryonic lethality
61 , 481–490 doi:10.1007 / s00239 - 004 - 0332 - 0 ( 2006 ) Deletion of Peg10 , an imprinted gene acquired from a retrotransposoncausesearly embryonic lethality
showing that the lack of both Ndr1 / Ndr2 ( called Ndr1/2-double null mutantscausesembryonic lethality
Knockout of the Derlin-1 and Derlin-2 genescausesembryonic lethality
Double knockout for SPHK1 and SPHK2causesembryonic lethality ( PubMed:16314531
from Meis1 deficiencyresultingfrom Meis1 deficiency
from disruption of both N - myc alleles in mouse zygotes , New Biolresultingfrom disruption of both N - myc alleles in mouse zygotes , New Biol
from disruption of both N - myc alleles in mouse zygotes " New Biologistsresultingfrom disruption of both N - myc alleles in mouse zygotes " New Biologists
from disruption of Zfp36L1resultingfrom disruption of Zfp36L1
from mouse Ikbkap ablationresultingfrom mouse Ikbkap ablation
analysis of competencepreventinganalysis of competence
analysis of the kidneypreventinganalysis of the kidney
analysis of paxpreventinganalysis of pax
analysis of a fluoroscopepreventinganalysis of a fluoroscope
from xYMO injectionresultingfrom xYMO injection
to hybrid male inviability in hybrids between Drosophila melanogaster and D. santomealeadsto hybrid male inviability in hybrids between Drosophila melanogaster and D. santomea
from the disruption of important genesresultingfrom the disruption of important genes
from genetic disruption of the GPCRresultingfrom genetic disruption of the GPCR
analysis of mouse mutations of thepreventinganalysis of mouse mutations of the
analysis of the gocad modelspreventinganalysis of the gocad models
analysis of animal capspreventinganalysis of animal caps
analysis of the emergency departmentpreventinganalysis of the emergency department
analysis of organ transplants between speciespreventinganalysis of organ transplants between species
analysis of animal bites and stings exsanguinationpreventinganalysis of animal bites and stings exsanguination
analysis of single or double cuffed catheterspreventinganalysis of single or double cuffed catheters
from combined genetic disruption of ATM and Prkdc or Kuresultsfrom combined genetic disruption of ATM and Prkdc or Ku
analysis of the optic stalk pfeffer the following principlespreventinganalysis of the optic stalk pfeffer the following principles
analysis of mutations affecting splicing of wt isoformspreventinganalysis of mutations affecting splicing of wt isoforms
analysis of organ induction and differentiation of podocytes in view of thepreventinganalysis of organ induction and differentiation of podocytes in view of the
a detailed analysis of their contribution to angiogenesis in adult animalspreventeda detailed analysis of their contribution to angiogenesis in adult animals
further analysis of HNF-4α function in β - cells ( 27preventsfurther analysis of HNF-4α function in β - cells ( 27
from disruption of both N - myc alleles in mouse zygtes " New Biologistresultingfrom disruption of both N - myc alleles in mouse zygtes " New Biologist
analysis of normal size this anomaly may occur in patients with diabetespreventinganalysis of normal size this anomaly may occur in patients with diabetes
analysis of cell types the intercalated and principal cells of the calf on dorsiflexion of thepreventinganalysis of cell types the intercalated and principal cells of the calf on dorsiflexion of the
analysis of the role of FAK in the late stage of embryonic development including angiogenesis in vivopreventedanalysis of the role of FAK in the late stage of embryonic development including angiogenesis in vivo
from disruption of the Frs2 alpha gene , which hinders further characterization of the role of FRS2 alpha in adult tissue function and homeostasisresultingfrom disruption of the Frs2 alpha gene , which hinders further characterization of the role of FRS2 alpha in adult tissue function and homeostasis
analysis of metanephric mesenchyme left and caudal genes of interest in and around the entire hindbrain and spinal cord injurypreventinganalysis of metanephric mesenchyme left and caudal genes of interest in and around the entire hindbrain and spinal cord injury
analysis of intrachain ionic interactions in the animal cap tissue treatment of children who suffer gastroduodenal ulceration or coagulopathies carepreventinganalysis of intrachain ionic interactions in the animal cap tissue treatment of children who suffer gastroduodenal ulceration or coagulopathies care
from the disruption of genes involved in double - strand break repair , including DNA ligase IV , Xrcc4 , Rad51 , and Brca1 ( 20 , 21 , 38 , 39resultingfrom the disruption of genes involved in double - strand break repair , including DNA ligase IV , Xrcc4 , Rad51 , and Brca1 ( 20 , 21 , 38 , 39
from disruption of both N - mycalleles in mouse zygotes Growth retardation and early death of β-1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cellsresultingfrom disruption of both N - mycalleles in mouse zygotes Growth retardation and early death of β-1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells
from the global loss of BMP4 early in embryogenesisresultsfrom the global loss of BMP4 early in embryogenesis
from placental defectsresultingfrom placental defects
from the cumulative effects of centrosome loss covaries with strength of polo alleleresultingfrom the cumulative effects of centrosome loss covaries with strength of polo allele
from a failure to mobilize maternal lipid storesmight resultfrom a failure to mobilize maternal lipid stores
from a defect in the hematopoietic systemoriginatedfrom a defect in the hematopoietic system