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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

blood - brain barrier disruption(passive) caused bybrain edema

destroy the blood - brain barrier integrityleadingto brain edema

a diseasecausedbrain edema

structural damage to the blood brain barrier [ 12leadingto the brain edema

an increase in blood brain barrier ( BBB ) permeability(passive) is caused byBrain edema

loss of the integrity of the blood - brain barrier ( BBB(passive) caused bybrain edema

Also , blood – brain – barrier damage may occurleadingto brain edema

The cellular mechanisms of secondary brain injury described abovecontributeto brain edema

Immunosuppression ( corticosteroidsto preventbrain edema

acute water intoxication [ 2(passive) caused bybrain edema

movement of water into the brain cells(passive) caused bybrain edema

the water homeostasisleadingto brain edema

the body watercontributesto the edema of the brain

Permeability of brain capillaries ( the Blood - Brain Barrier , BBB ) increases progressively in ischemia and reperfusionultimately leadingto brain edema

2005 Mild hypothermiapreventsbrain edema

traumatic brain injury or stroke(passive) caused bybrain edema

water accumulation in the brain because of BBB disruption after ischemic stroke [ 42(passive) is caused bybrain edema

that rapid changes in plasma and brain osmolalitycould resultin brain edema

Koyama R. Ischemic brain injuryleadsto brain edema

Fan Z. Ischemic Brain InjuryLeadsto Brain Edema

the pathologic statesleadingto brain edema

because concern would be expectedto causebrain edema

not given much watercan causebrain edema

an osmotic disturbance induced by the astrocytic accumulation of glutamineleadsto brain edema

increases astrocyte glutamine synthesiscausingbrain edema

cerebral ischemia and infarction(passive) caused bybrain edema

CA or cerebral ischemia(passive) caused bybrain edema

the occurrence of leaky blood vesselscausingedema in the brain

Severe brain injuryleadsto brain edema

brain injury / brain edema / thrombin / protease / aquaporin / 受容体 / 細胞反応 / グリオーマ Brain injury and brain tumorcausesbrain edema

brain injury and cerebral ischemia.29(passive) caused bybrain edema

Free fatty acidscausebrain edema

Hearing loss and brain tumor ganas Tinnituscausesbrain edema

hypoxic - ischemic encephalopathy ( HIE(passive) caused byBrain edema

an increase in intracellular or extracellular water(passive) is caused byBrain edema

The brain cells then retain waterresultingin brain edema

kidney function and water retention ... both of whichcan causeedema of the brain

These water shifts have traditionally been thoughtto contributeto brain edema

Impaired cerebral autoregulation in the presence of hypoxic cerebral vasodilation and altered permeability of the blood - brain barrier due to hypoxia - induced chemical mediators like histamine , arachidonic acid , and VEGFmay all contributeto brain edema

Symptoms Symptomsresultfrom brain edema

herniation and deathcausesherniation and death

to brain deathfinally leadingto brain death

to quick deathleadsto quick death

to intracranial hypertension and deathcan leadto intracranial hypertension and death

to morbidity and death associated with strokecontributes significantlyto morbidity and death associated with stroke

inflammation and oxidative stress(passive) caused byinflammation and oxidative stress

to both short - term and long - term issues , such as headache , memory loss , seizures and impaired speechcan leadto both short - term and long - term issues , such as headache , memory loss , seizures and impaired speech

to the clinical course of human brain tumor patientssignificantly contributesto the clinical course of human brain tumor patients

to neuronal death and neurological deterioration ... 9leadto neuronal death and neurological deterioration ... 9

from the death of neural substrates following a strokeresultingfrom the death of neural substrates following a stroke

in increased intracranial pressure and seizuresresultingin increased intracranial pressure and seizures

to uncal herniationleadingto uncal herniation

to swelling of brain cellsleadsto swelling of brain cells

to cerebellar herniation , compression of the brain stem , and death , especially in older individualscan leadto cerebellar herniation , compression of the brain stem , and death , especially in older individuals

to sever epileptic seizuresleadto sever epileptic seizures

Protects Against Neurological Symptoms(passive) Caused byProtects Against Neurological Symptoms

headache and the other symptoms of altitude sicknesscausesheadache and the other symptoms of altitude sickness

other problems such as vascular compromisecausingother problems such as vascular compromise

a rise in intracranial pressurecausesa rise in intracranial pressure

an increase in intracranial pressurecausesan increase in intracranial pressure

to patient symptoms such as headaches , nausea and vomiting , problems with speech , balance and seizurescontributesto patient symptoms such as headaches , nausea and vomiting , problems with speech , balance and seizures

in brain herniation into the craniotomy windowresultingin brain herniation into the craniotomy window

increased pressure inside the headcausingincreased pressure inside the head

seizures , coma , and even respiratory arrestcan causeseizures , coma , and even respiratory arrest

from cerebralschemia in SHR rats ( Kamiya , ( 1990 ) , Nippon Ika Daigaku Zasshiresultingfrom cerebralschemia in SHR rats ( Kamiya , ( 1990 ) , Nippon Ika Daigaku Zasshi

nausea and headachecan causenausea and headache

nausea in dialysiscan causenausea in dialysis

the brain swelling(passive) contributed bythe brain swelling

Second , increased intracranial pressure(passive) caused bySecond , increased intracranial pressure

severe headache and potentially life - threatening seizurescan causesevere headache and potentially life - threatening seizures

to seizures and loss of consciousness Acute kidney injuryLeadingto seizures and loss of consciousness Acute kidney injury

from blood clots and brain tumorscan resultfrom blood clots and brain tumors

Trauma , infections , tumors and compression(passive) caused byTrauma , infections , tumors and compression

from traumatic brain injury ( TBI ) or ischemia if uncontrolled exhausts volume reserve and leads to raised intracranial pressure and brain herniationresultingfrom traumatic brain injury ( TBI ) or ischemia if uncontrolled exhausts volume reserve and leads to raised intracranial pressure and brain herniation

from cerebral ischaemia ( Kamiya et al . , ( 1993resultingfrom cerebral ischaemia ( Kamiya et al . , ( 1993

from Brain Tumors Referring to our previous papersResultingfrom Brain Tumors Referring to our previous papers

malignant midline shift and compression of the basal cisterns on neuroimagingcausingmalignant midline shift and compression of the basal cisterns on neuroimaging

in serious brain damagemay resultin serious brain damage

to secondary injury in traumatic brain injury ( TBImay contributeto secondary injury in traumatic brain injury ( TBI

brain ischemia and hemorrhage into the brainmay also causebrain ischemia and hemorrhage into the brain

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Smart Reasoning:

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