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Qaagi - Book of Why

Causes

Effects

the activation of S - Cdk , which activates proteins that unwind the DNA and initiate its replication at replication origins(passive) is triggered byChromosome duplication

cell divisionresultingin chromosome duplication

o DNA replication occursresultingin chromosome duplication

an error that happens during the formation of the egg or sperm(passive) is caused byThe duplication on chromosome 17p11.2

Long repeats such as Alu sequences hinder chromosome pairing ,sometimes leadingto chromosome duplication

a sporadic mutation that occurs when the egg or the sperm is made(passive) is caused byChromosome 15q duplication

the presence of at least one additional maternally derived copy of the 15q11.2-q13(passive) caused bychromosome 15q duplication

Unresolved defects in the progression of replicationmay preventchromosome duplication

The cell cycle ... DNA synthesisresultsin chromosome duplication

abnormalities during mitosis(passive) is caused byChromosome duplication

Crosslinks are extremely toxic for cellspreventproper chromosome duplication

Tetraploid lines ... autumn crocuscauseschromosome duplication

an autosomal dominant pattern of inheritance of dysmyelinative neuropathy caused by overexpression of peripheral myelin protein 22 ,resultsfrom a chromosome 17p12 duplication

copy - number amplificationsoriginatingfrom chromosome duplication

Uniparental isodisomyresultingfrom chromosome duplication

a paternally derived unbalanced translocationleadingto duplication of chromosome 15pter

de novo rearrangementscausingduplication of the paternal chromosome

The processesleadto chromosome duplication

microarray testing in a fetus with a prenatally detected apparently balanced de novo translocation 46,XY , t(2;13)(q37;q32(passive) discovered bya chromosome 13q32.3 duplication

SRP061437 MECP2 duplication syndrome , a childhood neurological disorder characterized by autism , intellectual disability , motor dysfunction , anxiety and epilepsy(passive) is caused bySRP061437 MECP2 duplication syndrome , a childhood neurological disorder characterized by autism , intellectual disability , motor dysfunction , anxiety and epilepsy

SRP061436 MECP2 duplication syndrome , a childhood neurological disorder characterized by autism , intellectual disability , motor dysfunction , anxiety and epilepsy(passive) is caused bySRP061436 MECP2 duplication syndrome , a childhood neurological disorder characterized by autism , intellectual disability , motor dysfunction , anxiety and epilepsy

the oral mucosa(passive) caused bythe oral mucosa

increased chemotactic response towards isolated intestinal mucus layer and stronger adhesion to human intestinal epithelial cell line at an early phase of infection compared to wild type and a null mutant strainresultedincreased chemotactic response towards isolated intestinal mucus layer and stronger adhesion to human intestinal epithelial cell line at an early phase of infection compared to wild type and a null mutant strain

SRP061434 Reversal of MECP2 duplication syndrome using genetic rescue and antisense oligonucleotides [ Genetic Rescue Experiments ] MECP2 duplication syndrome , a childhood neurological disorder characterized by autism , intellectual disability , motor dysfunction , anxiety and epilepsy(passive) is caused bySRP061434 Reversal of MECP2 duplication syndrome using genetic rescue and antisense oligonucleotides [ Genetic Rescue Experiments ] MECP2 duplication syndrome , a childhood neurological disorder characterized by autism , intellectual disability , motor dysfunction , anxiety and epilepsy

la ( CMT1a(passive) is most likely caused byla ( CMT1a

a genetic disorder(passive) caused bya genetic disorder

CMT1A , the most common form of CMT(passive) is usually caused byCMT1A , the most common form of CMT

style and paper company diseases(passive) caused bystyle and paper company diseases

Charcot - Marie - Tooth neuropathy type 1a ( CMT1a(passive) is most likely caused byCharcot - Marie - Tooth neuropathy type 1a ( CMT1a

developmental delays including motor planning issues , expressive speech issues , sensory processing disorder , cognitive delayscan causedevelopmental delays including motor planning issues , expressive speech issues , sensory processing disorder , cognitive delays

the maximum number of chromosomes to be exceededwould causethe maximum number of chromosomes to be exceeded

A maidenhair fern individual from the same species due to became tetraploid due to an error in chromosomal doubling in meiosis meiosissetsA maidenhair fern individual from the same species due to became tetraploid due to an error in chromosomal doubling in meiosis meiosis

to the production of chromosomes bearing 2n chromatids without changing the chromosome numberleadingto the production of chromosomes bearing 2n chromatids without changing the chromosome number

from a failure of some aspect of the spindle apparatus that lines up and divides the chromosomes equally during division ( particularly during mieosis , the process that halves the number of chromosomes during gamete productionusually resultsfrom a failure of some aspect of the spindle apparatus that lines up and divides the chromosomes equally during division ( particularly during mieosis , the process that halves the number of chromosomes during gamete production

in two identical sister chromatids bound together by cohesin proteins at the centromereresultsin two identical sister chromatids bound together by cohesin proteins at the centromere

to the duplication of a region of DNA containing a geneleadsto the duplication of a region of DNA containing a gene

to the formation of a new gene under suitable selection pressurecan leadto the formation of a new gene under suitable selection pressure

to new functionsleadingto new functions

to the production of haploid gametesleadingto the production of haploid gametes

in doubled - haploid plantsresultingin doubled - haploid plants

in the formation of allopolyploidsresultingin the formation of allopolyploids

changes in function and alter protein interaction networksmay causechanges in function and alter protein interaction networks

to multiplication of the ERG11 geneleadingto multiplication of the ERG11 gene

an overexpression of the PMP22 genecausingan overexpression of the PMP22 gene

from overexpression of Glc7 in sds22 straincould have resultedfrom overexpression of Glc7 in sds22 strain

to the amplification of one or more of the rRNA operonscould have ledto the amplification of one or more of the rRNA operons

to developmental delays and intellectual disabilitiesleadsto developmental delays and intellectual disabilities

The multiploidy of sturgeon(passive) has been caused byThe multiploidy of sturgeon

severe health problemsusually causessevere health problems

The disease , named for Lupski and his BCM colleague Dr. Lorraine Potocki(passive) is caused byThe disease , named for Lupski and his BCM colleague Dr. Lorraine Potocki

to tumorigenesiscould contributeto tumorigenesis

to a defect in his heartleadingto a defect in his heart

from a familial t(10;13)(qtr;q14resultedfrom a familial t(10;13)(qtr;q14

this phenotypemay causethis phenotype

Adrian ’s delay in speech and learning(passive) might be caused byAdrian ’s delay in speech and learning

Ava 's issues(passive) are caused byAva 's issues

in cognitive and social deficits that are symptomatic of schizophreniaalso resultedin cognitive and social deficits that are symptomatic of schizophrenia

as far as we knowcausedas far as we know

in less severe symptomsresultsin less severe symptoms

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