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Qaagi - Book of Why

Causes

Effects

Long - term use of codeinecan leadto drug tolerance

Long term use of OxyContincan causetolerance for the drug

long - term use ... to dependencycreatestolerance for the drug

the possible long - term usecausingdrug tolerance

Ambien long term usecan leadto drug tolerance

internal cues(passive) triggered byBrief Drug tolerance

Disorder Regular use of these drugsoften leadsto " drug tolerance

Opioids alter the chemistry of the brainleadingto a drug tolerance

the long - term use of opioids for pain alleviation ... the brainleadsto drug tolerance

Repeated usecausestolerance for the drug

when long - term use of the drug alters the function of neurons in the brain(passive) is causedTolerance for a drug

Prolonged use of nitrocan leadto drug tolerance

overuse of stimulants , such as cocaineleadsto drug tolerance

Docherty , J. Increased amounts of smooth ER in liver cells ... the factorscan leadto drug tolerance

Regular use of heroincan causetolerance of the drug

Another side effect of these over the counter sleep aids iscausesdrug tolerance

the prodrug are rapidly depletedresultingin drug tolerance

Ask Erowid : ID 1794causestolerance to drugs

Regular use of sleeping pilloften leadsto drug tolerance

Regular use or misuse of ketaminecan resultin drug tolerance

Dilaudid abuseleadsto drug tolerance

McCormick F. AKT inactivationcausespersistent drug tolerance

Regular use of sedative - hypnotic drugscan often leadto drug tolerance

Decreased activity of the target functions in persisterswould leadto drug tolerance

Appetite suppressants alone ... more likelyto causedrug tolerance

This habituation of the body to the drugcreatestolerance to the drug

a long line of research on agents such as pentobarbital , d - amphetamine , and cocaine ... environmental factorsinfluencedrug tolerance

the conditioned stimulus ... the effect of the drugcontributeto drug tolerance

which can cause in a buildup of meth in a person ’s systemresultingin drug tolerance

Besides , because of this desensitization , the stimulation of the GPCR and eventually the therapeutic effect will be reached more difficultmight leadto drug tolerance

When stimulated by other addictive substances such as cocaine , the reward system distributes up to 10 times more dopamine , thusresultingto drug tolerance

When taken over a long period of time , the body will adjust to the presence of opioids insideoften resultingin drug tolerance

depletion of precursors or rebound effect following treatment cessation in the presence of marked elevation of glucagon(passive) caused bydrug tolerance

A long term exposure of our body to certain drugs especially during the treatment of chronic heart diseasesmay leadto drug tolerance

that , say , long - term cannabis use causes the body ’s cannabinoid receptors to become less responsivecreatestolerance to the drug

a gradual desensitization of these receptors to the drugs ,resultingin drug tolerance

Drug addictionleadsto drug tolerance

This CR ... the change in biological processescausestolerance to drugs

However , they appearedto causetolerance to the drugs

The decrease in antagonist potencies over timemight leadto drug tolerance

to physical dependence , addiction , abuse , and overdosemay leadto physical dependence , addiction , abuse , and overdose

in demand for more and culminates in addictionresultsin demand for more and culminates in addiction

to a dependency , which will then cause an addiction to formwill leadto a dependency , which will then cause an addiction to form

to physical dependency , addiction , abuse , and overdosecan leadto physical dependency , addiction , abuse , and overdose

to dependence and eventually an addiction to the substanceleadsto dependence and eventually an addiction to the substance

to greater and more frequent use , which can quickly spiral into dependence and addictionleadsto greater and more frequent use , which can quickly spiral into dependence and addiction

the user to consume more of the drug , speeding them down the path of addictioncausesthe user to consume more of the drug , speeding them down the path of addiction

to a physical dependency , drug addiction , abuse , and potentially overdosemay leadto a physical dependency , drug addiction , abuse , and potentially overdose

in taking higher than prescribed doses and addictioncan resultin taking higher than prescribed doses and addiction

to addiction , which is a condition that develops gradually over timeleadsto addiction , which is a condition that develops gradually over time

in dependence and addiction High risk of an overdose occurring Since fentanyl is highly potentresultingin dependence and addiction High risk of an overdose occurring Since fentanyl is highly potent

to requiring higher doses Physical dependence on the drug , which can cause withdrawal symptoms as well as addiction A fast or pounding heartbeatleadsto requiring higher doses Physical dependence on the drug , which can cause withdrawal symptoms as well as addiction A fast or pounding heartbeat

to physical dependency among userscan leadto physical dependency among users

alsocausesalso

to escalating usage Withdrawal symptomshas ledto escalating usage Withdrawal symptoms

in higher doses of the medicine to receive effectiveness over time [ 1resultin higher doses of the medicine to receive effectiveness over time [ 1

to dependence , which is characterized as having withdrawal symptoms when you stop taking the drugcan also leadto dependence , which is characterized as having withdrawal symptoms when you stop taking the drug

to increased overdose riskleadsto increased overdose risk

to persistence of symptoms and emergence of other side effects of conventional therapies.[2],[3leadingto persistence of symptoms and emergence of other side effects of conventional therapies.[2],[3

to drug dependenceleadsto drug dependence

them to take much higher dosage over the recommended levelleadingthem to take much higher dosage over the recommended level

in taking much higher dosage and eventually , overdoseresultsin taking much higher dosage and eventually , overdose

you to absorb higher doses , cheap coach bagscausesyou to absorb higher doses , cheap coach bags

increased self - dosage to achieve the same desired effectmay causeincreased self - dosage to achieve the same desired effect

in tolerance of another similarly - acting drugwill resultin tolerance of another similarly - acting drug

to drug overdose ( Kosten and George , 2002leadingto drug overdose ( Kosten and George , 2002

in using more than intended or for longer than intended Experiencing withdrawal symptoms when use is curtailed or slowedresultsin using more than intended or for longer than intended Experiencing withdrawal symptoms when use is curtailed or slowed

a chronic user to increasecausesa chronic user to increase

to physical dependence , in which the person ’s system adjusts to a new level of baseline functioning in the presence of the drugcan leadto physical dependence , in which the person ’s system adjusts to a new level of baseline functioning in the presence of the drug

in tolerance of another similarly - acting xanax prescription price drugwill resultin tolerance of another similarly - acting xanax prescription price drug

the user to increase the quantity consumedleadingthe user to increase the quantity consumed

in tolerance of another similarly - acting buy zolpidem 10 mg tablets drugwill resultin tolerance of another similarly - acting buy zolpidem 10 mg tablets drug

greater dependence and even an overdose on the drugmay causegreater dependence and even an overdose on the drug

the user to take more of it to experience the effect of the medicationcausesthe user to take more of it to experience the effect of the medication

to dependence , where you actually need the drugs just to function normallywill leadto dependence , where you actually need the drugs just to function normally

to dependence that can cause physical and psychological symptoms of withdrawalleadsto dependence that can cause physical and psychological symptoms of withdrawal

in tolerance to another drug that the user has never been exposed to beforecan resultin tolerance to another drug that the user has never been exposed to before

a person to want to take more of the drug more often and can contribute to patterns of misusemay then leada person to want to take more of the drug more often and can contribute to patterns of misuse

the user to increase his or her daily mushroom dosage to generate the drug ’s defined effectcan promptthe user to increase his or her daily mushroom dosage to generate the drug ’s defined effect

to the need for volume and physiological and psychological dependence on drugs leads to increased inappropriate behaviorleadsto the need for volume and physiological and psychological dependence on drugs leads to increased inappropriate behavior

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